Background Multiple myeloma, a malignancy of the antibody-secreting plasma cells, remains incurable by current therapy. However, proteasome inhibitor bortezomib and other new drugs are revolutionizing its treatment. It unclear why myelomas peculiarly sensitive to bortezomib, or what causes primary acquired resistance. The ‘unfolded protein response’ is necessary for folding assembly immunoglobulin chains in both normal malignant as well disposal incorrectly folded unpaired via...

The physicochemical parameters (free acidity, moisture content, sucrose hydroxymethylfurfural, reducing sugars, electrical conductivity, diastase activity and water-insoluble content), elements (Cu, Fe, Zn, Mn, Cr, Co, Ni, Se, K, Na, Ca, Mg) heavy metal/metalloid concentrations (Cd, Hg, Pb As) of 84 honeys (linden, multifloral, honeydew acacia) from Serbia, were analyzed using ICP-MS. Concerning the parameters, all tested found to meet European Legislation (EC Directive 2001/110). Potassium...

All over the world, especially in Western societies, table salt intake that is inordinately higher than acceptable level has been observed. An excess of Na human diet, mostly from processed foods, becoming “number one killer”, leading to increased blood pressure. Therefore, food industry faced with a need reduce nutrition an effort raise public health protection level. In this study, commercially available combination Na/K salts (COMB) at different concentrations was used as NaCl substitute...

The aim of this study was to determine the effects different temperatures and storage time on Staphylococcus aureus growth, sea gene expression, synthesis staphylococcal enterotoxin A (SEA) in pasteurized UHT-pasteurized milk. Pasteurized milk were inoculated with 3.98 log10 CFU/mL S. (ATCC 13565). Inoculated samples stored at 8°C, 15°C, 22°C for 24, 48, 72 h, respectively. SEA detected a fully automated miniVIDAS instrument using Enzyme-Linked Fluorescent Assay (ELFA) technology. patterns...

Abstract Recent views on the use of preservatives sorbic and benzoic acids their salts in meat products are presented from point accordance with current legislation Republic Serbia EU, food safety public health risks, mainstreams methodology for determination. These permitted to be added individually or combination, maximum level is applicable sum levels expressed as free acid. Currently set values recommended daily intake sorbate benzoate 25 mg/kg 5 mg/kg, respectively. vary depend...

In this study, the common carp fish were smoked in direct and indirect smoke chambers. Direct smokings craft chamber conducted four ways: without filter (Fo), with zeolite (Fz), granular activated carbon (Fc) gravel (Fg). The content of 16 different PAHs was analyzed using GCMS method. Addition zeolite, filters significantly reduced PAH levels (P < 0.05). Levels naphthalene, acenaphthylene, fluorine, phenanthrene fluoranthene by 42.14, 40.64, 42.5 (Naph), 49.81, 48.96, 48.96 (Acy), 32.71,...

Abstract This study was to determine the contents and any correlations of As, Cu, Zn, Fe, Cd Pb in multifloral honeys. Honey, among other bee products, is a good bioindicator since it can reveal connections between soil, plants honeybees. Ninety-two samples honey were collected from retail market during 2018 vegetation season analyzed mineral content. Analysis elements performed by inductively coupled plasma mass spectrometry (ICP-MS). The most abundant element with average concentration...

A new system that removes nitrogen from landfill leachate and other waste waters with similar properties has been proposed nitritation (i.e. oxidation of ammonium to nitrite) half the influent followed by chemical denitrification a reaction between equal amounts nitrite form gas. Chemical occurs at high concentrations reactions were studied in combination concentration step. Studied methods freezing/thawing evaporation/drying. is well-known inorganic chemistry observed natural systems....

Abstract Staphylococcus aureus is known worldwide as a frequent cause of mastitis in dairy cattle. Due to the production heath resistant enterotoxins, this pathogen also major food poisoning among humans, with symptoms often severe vomiting and diarrhea. The aim our study was determine prevalence enterotoxinproducing strains S. originating from samples cows subclinical clinical Republic Serbia. Furthermore, we analyzed type staphylococcal enterotoxin they produce phylogenetic relatedness...

Abstract This study was aimed at the investigation into influence of polyphenols on fermented sausages produced with and without nitrite addition, during storage which lasted for 280 days. Three types were formed three experimental groups: C – control usual composition containing nitrites; N+P - nitrites polyphenols; P nitrite-free added polyphenols. The proximate chemical all groups in range that dry sausages. contained 0.3 mg per kg, while 54.8 mg/kg 52.2 mg/kg, respectively....

In recent years, countries in Southeast Europe are facing climate changes characterized by extreme hot weather, which contribute to the increased frequency of Aspergillus species. Because these changes, parasiticus was isolated, for first time, from maize grain Serbia (Nikolic et al, 2018). The presence black powdery mycelia on ears indicated occurrence species genus section Nigri, led need detailed identification fungi. Disease incidence ranged 10 and 15% August 2013. Maize with symptoms...

This study aimed to investigate antimicrobial resistance of Salmonella Infantis isolates from poultry carcasses in Serbia. A total 48 were examined for resistance. panel 10 antibiotics was selected testing. Isolates showed sulfamethoxazole, ceftazidime and cefotaxime (100%). However, the highest number sensitive chloramphenicol. The usage food producing animals could result pathogenic bacteria especially spp. poultry, which may be transmitted humans through chain increase risk treatment failures.

For the successful validation and verification of HACCP system, a food business operator is obliged, among other duties, to have continuous microbiological data carcasses which are followed by certain dynamic that subject himself prescribed. To obtain these data, it necessary perform systematic monitoring indicator microorganisms. The most important meat hygiene indicators Total Viable Counts (TVC) Enterobacteriaceae (EC). TVC defined as overall slaughter (equipment, environment, tools,...

Nitrites are inorganic salts widespread in water, fruits, vegetables, meat and products. Application of nitrites the industry is necessary for multiple reasons. They suppress development some microorganisms food a source nitrogen oxide that widely involved physiological functions metabolism, intake energy balance. On other hand, can produce nitrosamines increase risk cancer. During regular quality control 2016-2018, 972 samples products were analysed verified compliance with regulations...

Abstract The first case of a severe acute respiratory syndrome caused by coronavirus-2 was reported in December 2019 China. disease spread globally quickly, causing the 2019–2021 COVID-19 pandemic. meat industry became concerned over possibility transmitting virus slaughterhouse environment. level air exchange strongly affects distribution SARS-CoV-2 aerosols within slaughterhouses. adsorption on surface frozen is dictated mainly interplay electrostatic forces between virion and tissue (pH)...

The effects of deep frying in sunflower oil or pork fat on the fatty acids (FAs) silver carp (Hypophthalmichthys molitrix) and common (Cyprinus carpio) fillets were determined. use for increased proportion polyunsaturated (PUFAs) saturated (SFA), respectively, fish fillets. In fried fillets, linoleic acid content (C18:2n-6) after oil, while n-3 PUFAs, particular C20:5n-3 (EPA) C22:6n-3 (DHA), decreased compared with their contents raw apparent retention values PUFAs higher (69-78%) than...

Abstract The production and trade of meat preparations (minced semi-finished products, including fresh sausages) are registering significant annual increases in Serbia. There is an increasing number specialized plants, as well suppliers who directly supply consumers with this type preparation. aim paper to determine the microbiological risks process by taking samples from retail facilities order verify HACCP compliance. systems good hygiene practices their pre-requisite programs, require...

The goal of this study was to investigate the influence reducing sodium chloride content in pork stew by partial replacement with potassium or ammonium chloride, a target achieve optimal salty taste. trial consisted five groups. In control stew, only added. group 1, one third replaced chloride; 2, half 3, reduced and quarter added compared 4, 62.5%, same weight as Sensory evaluation performed ten trained assessors using numeric scales. Evaluations colour acceptability consistency were...

Broiler meat quality depends on the interaction of several factors, including genotype, slaughter age/body weight, pre-slaughter handling, and method. The aim this study was to determine effect weight yield broilers. material consisted 42 broilers, classified into three groups: lighter (<2500 g), medium (2500–3000 g) heavier (>3000 g). following parameters were measured: cold carcass breast before after deboning, skin bone weights, thigh drumstick weights. Meat pH (M. pectoralis major)...

Abstract Plants from the moderate climate zone are rarely used as seasoning in pasteurised sausages. Seasoning plants of family Lamiaceae belong to this group (marjoram, basil, savory, sage, thyme). One reasons these herbs season meat products is presence plant pigment, chlorophyll that can have undesirable influence on colour, odour and taste products. The aim paper was assess basil vacuum-packed frankfurters during 28 days storage. Powdered, dried (0.1%, 0.3% 0.5%) added while control were...