A5044785988- Connexins and lens biology
- Intraocular Surgery and Lenses
- Corneal surgery and disorders
- Aldose Reductase and Taurine
- Calpain Protease Function and Regulation
- Retinal and Macular Surgery
- Advanced Glycation End Products research
- Advanced Chemical Sensor Technologies
- Atmospheric chemistry and aerosols
- Glaucoma and retinal disorders
- Metabolism and Genetic Disorders
- Connective tissue disorders research
- Yersinia bacterium, plague, ectoparasites research
- Arsenic contamination and mitigation
- Protein Interaction Studies and Fluorescence Analysis
- Cell Adhesion Molecules Research
- Organ Transplantation Techniques and Outcomes
- RNA Interference and Gene Delivery
- Signaling Pathways in Disease
- Nicotinic Acetylcholine Receptors Study
- Analytical Chemistry and Chromatography
- Anorectal Disease Treatments and Outcomes
- Ocular Surface and Contact Lens
- Metabolomics and Mass Spectrometry Studies
- Mass Spectrometry Techniques and Applications
Stony Brook University
2023-2024
University of East Anglia
1987-2004
Abstract. Proton-transfer-reaction time-of-flight mass spectrometry (PTR-ToF-MS) is a technique commonly used to measure ambient volatile organic compounds (VOCs) in urban, rural, and remote environments. PTR-ToF-MS known produce artifacts from ion fragmentation, which complicates the interpretation quantification of key atmospheric VOCs. This study evaluates extent fragmentation other ionization processes impact urban measurements ions typically assigned isoprene (m/z 69, C5H8H+),...
Abstract. Proton-transfer-reaction time-of-flight mass spectrometry (PTR-ToF-MS) is a technique commonly used to measure ambient volatile organic compounds (VOCs) in urban, rural, and remote environments. PTR-ToF-MS known produce artifacts from ion fragmentation, which complicates the interpretation quantification of key atmospheric VOCs. This study evaluates extent fragmentation other ionization processes impacts urban measurements ions typically assigned isoprene (m/z 69, C5H8H+),...
Conference Article| November 01 1991 Calcium-induced degradation of the lens cytoskeleton Julia M. Marcantonio; Marcantonio 1School Biological Sciences, University East Anglia, Norwich NR4 7TJ, U.K. Search for other works by this author on: This Site PubMed Google Scholar George Duncan Biochem Soc Trans (1991) 19 (4): 1148–1150. https://doi.org/10.1042/bst0191148 Article history Received: June 07 Views Icon contents Figures & tables Video Audio Supplementary Data Peer Review Share Facebook...
The ability of normal and cataractous human lenses to accumulate amino acids synthesize proteins was studied under organ culture conditions. As expected, regulate their internal ion levels, against a concentration gradient, continue even in advanced age (> 60 yrs).The fell basically into two groups. Those with low sodium calcium content behaved similar manner lenses, but high contents showed markedly reduced acid synthesized less molecular weight protein. They incorporated, however, much...
AbstractThe 115kDa cytoskeletal beaded filament protein of bovine lens fibres is degraded during opacification induced by increased internal calcium. The monoclonal antibody R2D2 to this has been used in whole lenses and native homogenates follow the process degradation production break-down products. In opaque outer cortex with an Ca2+ 2.0mM, both parent main product (57kDa) were reduced amount almost 60%. No additional products detected antibody. When incubated overnight 10mM could no...
Ionic homeostasis is essential to lens clarity and the epithelium plays a large part in homeostasis, through vectorial transport. In most epithelia maintenance of function depends on cytoskeleton. Capsule/epithelium preparations from human donor lenses have been used for immunohisto-chemical investigations both normal epithelial cell cytoskeletal structure, structural changes induced by increasing calcium. A sustained increase intracellular calcium, incubation with A23187 W7, led loss...