David Mikhail

ORCID: 0009-0009-0831-1915
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About
Contact & Profiles
Research Areas
  • Retinal Imaging and Analysis
  • Artificial Intelligence in Healthcare and Education
  • Corneal surgery and disorders
  • Corneal Surgery and Treatments
  • Glaucoma and retinal disorders
  • COVID-19 diagnosis using AI
  • Retinal and Optic Conditions
  • Ocular Surface and Contact Lens
  • Digital Imaging for Blood Diseases
  • Retinal and Macular Surgery
  • Ophthalmology and Visual Health Research
  • Health Systems, Economic Evaluations, Quality of Life
  • Clinical Reasoning and Diagnostic Skills
  • Machine Learning in Healthcare
  • Ocular Infections and Treatments

University of Toronto
2024-2025

Université de Montréal
2024

This study assesses the proficiency of Generative Pre-trained Transformer (GPT)-4 in answering questions about complex clinical ophthalmology cases.

10.1136/bjo-2023-325053 article EN British Journal of Ophthalmology 2024-02-16

Purpose: To compare the performance and cost-effectiveness of DeepSeek-R1 with OpenAI o1 in diagnosing managing ophthalmology clinical cases. Study Design: Cross-sectional evaluation. Methods: A total 300 cases spanning 10 different subspecialties were collected from StatPearls. Each case presented a multiple-choice question regarding diagnosis or management case. was accessed through its public chat-based interface, while queried via an Application Program Interface (API) standardized...

10.1101/2025.02.10.25322041 preprint EN cc-by-nd medRxiv (Cold Spring Harbor Laboratory) 2025-02-12

We read with great interest the article “Clinical Outcomes and Early Postoperative Complications in Boston Type I Keratoprosthesis Implantation: A Retrospective Study” by Krysik et al [...]

10.3390/jcm14051551 article EN Journal of Clinical Medicine 2025-02-26

To assess the performance of Chat Generative Pre-Trained Transformer-4 in providing accurate diagnoses to retina teaching cases from OCTCases.

10.1016/j.xops.2024.100556 article EN cc-by-nc-nd Ophthalmology Science 2024-05-23

To evaluate the performance of large language models (LLMs), specifically Microsoft Copilot, GPT-4 (GPT-4o and GPT-4o mini), Google Gemini (Gemini Advanced), in answering ophthalmological questions assessing impact prompting techniques on their accuracy. Prospective qualitative study. Advanced). A total 300 from StatPearls were tested, covering a range subspecialties image-based tasks. Each question was evaluated using 2 techniques: zero-shot forced (prompt 1) combined role-based...

10.1016/j.jcjo.2025.01.001 article EN cc-by-nc-nd Canadian Journal of Ophthalmology 2025-02-01

Mikhail, David MD(C), MSc(C); Milad, Daniel MD; Harissi-Dagher, Mona MD, FRCSC Author Information

10.1097/ico.0000000000003872 article EN Cornea 2025-03-18

Objectives: The integration of multimodal capabilities into GPT-4 represents a transformative leap for artificial intelligence in ophthalmology, yet its utility scenarios requiring advanced reasoning remains underexplored. This study evaluates GPT-4’s performance on open-ended diagnostic and next-step tasks complex ophthalmology cases, comparing it against human expertise. Methods: was assessed across three arms: (1) text-based case details with figure descriptions, (2) cases text...

10.3390/jpm15040160 article EN Journal of Personalized Medicine 2025-04-21
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