A5102884821- Inflammatory Myopathies and Dermatomyositis
- Eosinophilic Disorders and Syndromes
- Immunodeficiency and Autoimmune Disorders
- Skin Diseases and Diabetes
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Dermatological and Skeletal Disorders
- Heterotopic Ossification and Related Conditions
- Vasculitis and related conditions
China-Japan Friendship Hospital
2020-2025
Objective: To evaluate the efficacy of tocilizumab (TCZ) in adult patients with refractory immune-mediated necrotizing myopathies (IMNMs) and investigate possible predictive biomarkers response to treatment TCZ. Methods: Patients IMNM were enrolled this open-label pilot observational study received intravenous TCZ treatment. The clinical was assessed after 6 months according 2016 American College Rheumatology–European League Against Rheumatism (ACR–EULAR) criteria for dermatomyositis...
Objective: To investigate the clinical features and prognosis of anti-melanoma differentiation-related gene 5 (MDA5) antibody anti-cyclic citrullinated peptide (CCP) double-positive dermatomyositis (DM) (MDA5+/CCP+ DM). Methods: A retrospective analysis 264 consecutive cases MDA5+ DM hospitalized from March 2018 to 2022, patients with anti-CCP antibodies were screened out. Patients MDA5+/CCP- served as control. Propensity score matching was used compare features, well treatment survival...
Abstract Objective To investigate the role of bronchoalveolar lavage (BAL) in DM-associated interstitial lung disease (ILD). Methods We retrospectively reviewed medical records patients with DM-ILD who underwent bronchoscopy between October 2015 and September 2019. then collated clinical features, laboratory data findings. The follow-up study was terminated on 1 May 2020. Results A total 113 were included this study, including 27 acute/subacute pneumonia (A/SIP) 86 chronic (CIP). A/SIP group...
Abstract Objective The occurrence of calcinosis cutis as a clinical feature dermatomyositis in adult patients is not well understood. Cohort studies with are rare. We systematically describe the features, treatments and outcomes calcinosis. Methods initially enrolled 627 DM patients. Of those enrolled, 35 (5.6%) were found to have analysed features associated this subgroup. risk factors using Poisson regression model. Results Multivariate analysis showed that younger age at disease onset...
To investigate the role of soluble interleukin-2R (sIL-2R) in idiopathic inflammatory myopathies (IIM).Serum sIL-2R levels were measured 74 dermatomyositis (DM), 16 immune-mediated necrotizing myopathy (IMNM), 24 rheumatoid arthritis (RA), 20 systemic lupus erythematosus (SLE), and healthy controls (HCs) by chemiluminescent immunometric assay. Clinical features laboratory data collected from electronic medical record. Disease activity was evaluated using physician global disease myositis...
Journal Article Corrected proof Cobblestone airways in eosinophilic granulomatosis with polyangiitis Get access Sizhao Li, Li Department of Rheumatology, Key Laboratory Myositis, China-Japan Friendship Hospital, Beijing, China https://orcid.org/0009-0009-2129-2202 Search for other works by this author on: Oxford Academic PubMed Google Scholar Shiwei Qumu, Qumu Respiratory and Critical Care Medicine, Beijing Xin Lu Correspondence to: Lu, #2 Ying-Hua East Street, Chaoyang District, 100029,...