A5093346184- Connexins and lens biology
- Ion channel regulation and function
- Neuroscience and Neuropharmacology Research
- Neurobiology and Insect Physiology Research
University of Oregon
2023
Electrical synapses are neuronal gap junction (GJ) channels associated with a macromolecular complex called the electrical synapse density (ESD), which regulates development and dynamically modifies transmission. However, proteomic makeup molecular mechanisms utilized by ESD that direct formation not well understood. Using Mauthner cell of zebrafish as model, we previously found intracellular scaffolding protein ZO1b is member ESD, localizing postsynaptically, where it required for GJ...
Abstract Electrical synapses are neuronal gap junction (GJ) channels associated with a macromolecular complex called the electrical synapse density (ESD), which regulates development and dynamically modifies transmission. However, proteomic makeup molecular mechanisms utilized by ESD that direct formation not well understood. Using Mauthner cell of zebrafish as model, we previously found intracellular scaffolding protein ZO1b is member ESD, localizing postsynaptically, where it required for...