A5078121899- Protease and Inhibitor Mechanisms
- Free Radicals and Antioxidants
- Inflammatory mediators and NSAID effects
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Electron Spin Resonance Studies
- Nitric Oxide and Endothelin Effects
- Sensory Analysis and Statistical Methods
- Apelin-related biomedical research
- Pancreatitis Pathology and Treatment
- Blood Coagulation and Thrombosis Mechanisms
- Youth, Drugs, and Violence
- Rabbits: Nutrition, Reproduction, Health
- Neuroscience, Education and Cognitive Function
- Comparative Animal Anatomy Studies
- Antioxidant Activity and Oxidative Stress
- Receptor Mechanisms and Signaling
Universidade Federal de Santa Maria
2025
European Union of Medical Specialists
2012
Universidade Paranaense
2001-2002
McMaster University
1999-2000
Abstract Introduction: Insulin resistance (IR) is associated with diabetic kidney disease (DKD), and normoalbuminuric patients may present renal tubular damage insulin (RTDAIR). In this context, the injury molecule-1 (KIM-1) emerges as a useful biomarker for assessing damage. Objective: To investigate role of KIM-1 in detection RTDAIR patients, well its relationship HOMA-IR. Methodology: This was cross-sectional study involving 82 T2DM, divided into two groups according to Laboratory tests...
Resumo Introdução: A resistência à insulina (RI) está associada doença renal diabética (DRD) e pacientes normoalbuminúricos podem apresentar lesão tubular (RTDAIR). Nesse contexto, a molécula de renal-1 (KIM-1) se apresenta como um marcador útil para avaliação da tubular. Objetivo: Investigar o papel do KIM-1 na detecção RTDAIR em normoalbuminúricos, bem sua relação com HOMA-IR. Metodologia: Estudo transversal envolvendo 82 DM2 divididos dois grupos pelo Foram realizados exames laboratoriais...
Cumulative concentration‐effect curves for the selective prostanoid TP receptor agonist U46619 and six isoprostanes were constructed in human isolated umbilical artery. All compounds except 8‐iso‐PGF 3α produced concentration‐dependent contractions. The contractile response to increased with each cumulative addition up a point, after which subsequent reduced contraction below previous level. This [downturn] curve did not occur U46619. potencies of tested as follows ( p EC 50 ±s.e.mean):...
5‐HT and the prostanoid TP receptor agonists, U46619 I‐BOP, constricted human umbilical artery with pEC 50 values of 7.3±0.2, 6.7±0.1, respectively. The selective antagonist, GR32191 (0.1 μ M ), shifted concentration‐effect curves to I‐BOP right, but had no effect on response 5‐HT. natural prostaglandins, PGF 2α PGE 2 , caused concentration‐dependent contraction 5.2±0.2 4.9±0.2, PGD was a partial agonist 5.24±0.03. ) inhibited responses all these compounds suggesting that they produce by...
El estomago realiza movimientos caracterizados por potentes ondas peristalticas lentas, utiles en la mezcla del bolo alimenticio, digestion mecanica y su lenta liberacion el piloro. control de este movimiento se accion hormonal actividad nerviosa, destacando inervacion intriseca que representan las neuronas plexo mioenterico. Considerando un estado desnutricion puede provocar alteraciones morfologicas, incluso neuronales, ha propuesto este trabajo, con objetivo verificar los efectos...
La morfologia del estomago puede variar de una especie a otra, en funcion sus habitos alimenticios, constitucion celular la mucosa pared estomacal y las funciones realizadas por celulas constituyentes. Variaciones morfofuncionales existentes entre los animales escala filogenetica, nos llevaron investigar glandular conejos. Utilizamos estomagos 32 conejos (Oryctolagus cuniculus), jovenes, raza Neozelandes Blanco, provenientes Estancia Experimental Iguatemi, Universidad Estadual Maringa,...
O presente artigo traz uma revisao sobre os efeiros do alcoolismo cronico o pâncreas. Fica evidente que a acao prolongada alcool estrutura pâncreas leva modificacoes morfologicas irreversiveislevando perda progressiva das funcoes pancreaticas ex´crina e endocrina, estabelecendo quadros de pancreatites câncer.