Siwen Huang

ORCID: 0009-0009-2909-1624
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About
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Research Areas
  • Poxvirus research and outbreaks
  • Catalytic C–H Functionalization Methods
  • COVID-19 Clinical Research Studies
  • SARS-CoV-2 and COVID-19 Research
  • Vaccine Coverage and Hesitancy
  • Alkaloids: synthesis and pharmacology
  • Virology and Viral Diseases
  • Chemical synthesis and alkaloids
  • HIV/AIDS Research and Interventions
  • Long-Term Effects of COVID-19
  • Asymmetric Hydrogenation and Catalysis
  • Sex work and related issues
  • Diabetes and associated disorders
  • Gut microbiota and health
  • Influenza Virus Research Studies
  • Tryptophan and brain disorders
  • HIV, Drug Use, Sexual Risk
  • HIV Research and Treatment
  • Medical Device Sterilization and Disinfection
  • Supercapacitor Materials and Fabrication
  • International Environmental Law and Policies
  • Erosion and Abrasive Machining
  • Control and Dynamics of Mobile Robots
  • Criminal Justice and Corrections Analysis
  • Neurological Disorders and Treatments

Vanke (China)
2023-2025

Tsinghua University
2023-2025

Shenyang Pharmaceutical University
2021-2025

Guangxi Normal University
2025

Trinity University
2024

Hong Kong University of Science and Technology
2024

University of Hong Kong
2024

Shenzhen Institutes of Advanced Technology
2024

Chinese Academy of Sciences
2024

University of Chinese Academy of Sciences
2024

To study the GI symptoms in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infected patients.We analysed epidemiological, demographic, clinical and laboratory data of 95 cases with SARS-CoV-2 caused disease 2019. Real-time reverse transcriptase PCR was used to detect presence faeces tissues.Among patients, 58 exhibited which 11 (11.6%) occurred on admission 47 (49.5%) developed during hospitalisation. Diarrhoea (24.2%), anorexia (17.9%) nausea were main five (5.3%), (5.3%)...

10.1136/gutjnl-2020-321013 article EN other-oa Gut 2020-04-02

The new-generation flexible aqueous zinc-ion batteries require enhanced mechanical properties and ionic conductivities at low temperature for practical applications. This fundamentally means that it is desired the hydrogel electrolyte possesses antifreezing merits to resist flexibility loss performance decrease subzero temperatures. Herein, a highly polysaccharide realized in situ regulated through Hofmeister effect with low-concentration Zn(ClO4 )2 salts satisfy abovementioned requirements....

10.1002/adma.202110140 article EN Advanced Materials 2022-02-05

Abstract The new coronavirus (SARS-CoV-2) outbreak originating from Wuhan, China, poses a threat to global health. While it’s evident that the virus invades respiratory tract and transmits human through airway, other viral tropisms transmission routes remain unknown. We tested RNA in stool 73 SARS-CoV-2-infected hospitalized patients using rRT-PCR. 53.42% of positive stool. 23.29% remained feces even after decreased undetectable level tract. was also detected gastrointestinal tissues....

10.1101/2020.02.17.20023721 preprint EN cc-by-nc-nd medRxiv (Cold Spring Harbor Laboratory) 2020-02-20

Tricomponent cobalt(salen)-catalyzed carbofunctionalization of unsaturated substrates by radical-polar crossover has the potential to streamline access broad classes heteroatom-functionalized synthetic targets, yet reaction platform remained elusive, despite well-developed analogous hydrofunctionalizations mediated high-valent alkylcobalt intermediates. We report herein development a cobalt(salen) catalytic system that enables carbofunctionalization. The entails tricomponent decarboxylative...

10.1021/jacs.3c14828 article EN Journal of the American Chemical Society 2024-02-21

Nanocarrier antigen-drug delivery system interacts specifically with immune cells and provides intelligent modes to improve antigen efficiency facilitate progression. However, these nanoparticles often have weak adhesion cells, followed by insufficient cell absorption, leading a failed response. Inspired the structure function of viruses, virus-like mesoporous silica (VMSNs) were prepared simulating surface structure, centripetal-radialized spike rough topology virus co-acted toll-like...

10.1080/10717544.2023.2183814 article EN cc-by Drug Delivery 2023-02-27

High-speed overtaking is one of the structured driving scenarios autonomous vehicles (AVs), and safety real-time control requirements must be fulfilled during this scenario. In article, we develop an path-planning tracking framework for AVs based on improved artificial potential field (APF) fast iterative model predictive (MPC). The APF used to plan a feasible, high-speed path by considering constraints vehicle dynamics introducing adjustment factor into function avoid local optimization...

10.1109/tte.2023.3269602 article EN IEEE Transactions on Transportation Electrification 2023-04-24

Background The worldwide human monkeypox (mpox) outbreak in 2022 mainly affected men who have sex with (MSM). In China, young (YMSM) were at a potential high risk of mpox infection due to their sexual activeness and the eased COVID-19 restrictions end 2022. Objective This study aimed investigate behavioral intention receiving vaccination undergoing testing 4 different scenarios explore associations background theory–related factors among Chinese YMSM. Methods An online cross-sectional survey...

10.2196/47165 article EN cc-by JMIR Public Health and Surveillance 2024-03-19

Abstract Diabetic foot ulcer is a serious complication of diabetes. Excessive accumulation advanced glycation end products (AGEs) one the critical pathogenic factors in postponing diabetic wound healing. The main mechanisms AGEs include inducing cellular dysfunction, prolonging inflammatory response, increasing oxidative stress and reducing endogenous nitric oxide (NO) production. Combination therapy blocking deleterious effects supplementing exogenous NO hypothesized to promote Here, we...

10.1093/rb/rbae062 article EN cc-by Regenerative Biomaterials 2024-01-01

China has enacted subnational smoke-free legislations, which requires compliance evaluations to provide data for future implementation planning. This study comprehensively assessed regulation in Xining Western China. Conducted November and December 2023, the used a mixed-methods design. Quantitative surveys of observing existence 'no evidence smoking' were completed by trained investigators 1007 venues (including 2553 indoor 55 outdoor areas). PM2.5 concentration assessments smoking...

10.1136/tc-2024-059077 article EN Tobacco Control 2025-03-20

Introduction of alkyl substituents onto nucleophilic nitrogen atoms in amines is a central synthetic strategy for increasing molecular complexity and structural diversity medicinal chemistry, organic synthesis, materi-als science. Although the direct transfer stereogenic group atom by N-alkylation one most efficient approaches to asymmetric C(sp3)–N bond formation, few methods are available enan-tioconvergent with racemic reagents. We report herein, previously unex-plored enantioconvergent...

10.26434/chemrxiv-2025-psqr7 preprint EN 2025-04-28

Li, Xiaofeng MD, PhD1; Huang, Siwen BMed1; Lu, Jing MMed1; Lai, Renxu Zhang, Zhenyi Lin, Xianqi Zheng, Xiaobin PhD2; Shan, Hong PhD3,4,5 Author Information

10.14309/ajg.0000000000000757 article EN The American Journal of Gastroenterology 2020-07-20

Submerged cavitating jets can effectively remove marine organisms from ship hulls without damaging the surface paint. To enhance cleaning efficiency of jets, selection an appropriate nozzle structure and design efficient device are crucial. In this study, submerged cavitation effect different nozzles was analyzed by numerical simulation. The actual efficacy confirmed through erosion experiments as well. simulation experiment showed that shear nozzle, absent a pre-shrinking section featuring...

10.3390/app14041433 article EN cc-by Applied Sciences 2024-02-09

Abstract The 2022 multi‐country mpox outbreak raised public concern globally. Self‐isolation and informing close contacts after developing mpox‐related symptoms are critical measures in controlling the outbreak. This study investigated behavioral intentions of self‐isolation associated factors among young men who have sex with (YMSM) aged 18−29 years China. cross‐sectional was conducted 2493 YMSM six provincial regions China from September 10th to 30th, 2022. Descriptive logistic analyses...

10.1002/jmv.29470 article EN Journal of Medical Virology 2024-02-01

Abstract The mpox outbreak since 2022 had attacked the community of men who have sex with (MSM) heavily. This large cross‐sectional study investigated levels and associated factors risk perception among young MSM (YMSM) aged 18–29 years in six provincial regions China September 2022. participants were recruited via facility‐based sampling. Mpox was measured by perceived susceptibility severity mpox. Geodetector used to measure stratified heterogeneity perception. Univariate multivariable...

10.1002/jmv.29057 article EN Journal of Medical Virology 2023-08-01

The total syntheses of aspidospermidine, N-methylaspidospermidine, N-acetylaspidospermidine, and aspidospermine were achieved from a common pentacyclic indoline intermediate. intermediate was synthesized on gram scale through Stork-enamine alkylation 1H-pyrrolo[2,3-d]carbazole derivatives, which prepared Brønsted acid-catalyzed tandem cyclization tryptamine-ynamide. scalable synthesis afforded facile access practical approach to the Aspidosperma indole alkaloid family.

10.1021/acs.orglett.1c02287 article EN Organic Letters 2021-08-02

Background. No consensus exists regarding which procedures should be performed to disinfect endoscopes and working platforms after COVID-19 patients have undergone endoscopy. Methods. We analyzed the disinfection quality of 11 had Conclusions. For endoscopic preprocessing at bedside, a key step is using multienzyme stock solution. The nucleic acid tests for endoscopists, washers, endoscopes, were all negative. Based on our experience with who endoscopy, we provide an reprocessing method...

10.1155/2020/9869742 article EN cc-by Gastroenterology Research and Practice 2020-12-31

In recent years, due to a number of notorious sex offense cases against minors, new punitive public attitude emerged in China and pressed for harsher crackdown punishment offenders. particular, an “engagement prostitution with minor” law (Article 360 the Criminal Law) was targeted as “unjust” based on belief that offenders such crimes often received “lenient” punishment, many called its abolition. this study, 440 adjudicated cases, we examine potential differences across three offenses...

10.1177/0306624x15616220 article EN International Journal of Offender Therapy and Comparative Criminology 2015-11-27
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