Chih-Chun Lee

ORCID: 0009-0009-3920-2607
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About
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Research Areas
  • Vascular Tumors and Angiosarcomas
  • Virology and Viral Diseases
  • Peripheral Neuropathies and Disorders
  • Eosinophilic Disorders and Syndromes
  • Infectious Aortic and Vascular Conditions
  • Drug-Induced Adverse Reactions
  • IgG4-Related and Inflammatory Diseases
  • Mast cells and histamine
  • Vascular Procedures and Complications
  • Urticaria and Related Conditions
  • vaccines and immunoinformatics approaches
  • Contact Dermatitis and Allergies
  • Tryptophan and brain disorders
  • Pediatric health and respiratory diseases
  • Aortic aneurysm repair treatments
  • Bipolar Disorder and Treatment
  • Wound Healing and Treatments
  • Autoimmune Neurological Disorders and Treatments
  • Long-Term Effects of COVID-19
  • Psoriasis: Treatment and Pathogenesis
  • Electroconvulsive Therapy Studies
  • Cancer, Stress, Anesthesia, and Immune Response
  • Neuroendocrine Tumor Research Advances
  • interferon and immune responses
  • Multiple and Secondary Primary Cancers

Emory University
2025

Children's Healthcare of Atlanta
2025

Chang Gung Memorial Hospital
2022-2025

Chang Gung University
2024

Taipei City Hospital
2024

Taipei Municipal YangMing Hospital
2024

Ministry of Health Labour and Welfare
2024

Keelung Chang Gung Memorial Hospital
2022-2023

University of Indianapolis
2023

Indiana University – Purdue University Indianapolis
2023

Kimura's disease (KD) is an uncommon lymphoproliferative fibroinflammatory disorder. Patients present with head and neck subcutaneous nodules or without lymphadenopathy. Peripheral blood eosinophilia elevated serum immunoglobulin E (IgE) levels are typical. This study was designed to delineate the clinicopathological features, pattern of care, course 23 Taiwanese patients KD.We retrospectively analyzed clinical data consecutive cases (16 male 7 female; age at diagnosis: 12-77 years) KD...

10.3389/fmed.2022.1069102 article EN cc-by Frontiers in Medicine 2022-12-29

Background: Secondhand smoke exposure (SHSe) is a public health threat for people with cystic fibrosis (CF) and other lung diseases. Primary smoking reduces CFTR channel function, the causative defect in CF. We reported that SHSe worsens respiratory nutritional outcomes CF by disrupting immune responses metabolic signaling. Recently, electronic cigarette (e-cigs) usage caregivers peers has increased rapidly, causing new secondhand e-cig vape exposures. vaping associated immunologic deficits...

10.1152/ajplung.00328.2024 article EN cc-by AJP Lung Cellular and Molecular Physiology 2025-01-21

Abstract Cutaneous delayed drug hypersensitivity reactions (DHRs) are common iatrogenic events with potentially life-threatening consequences. Delayed DHRs encompass diverse phenotypes and can be classified by their distinct T-cell responses to antigens. Interaction between the immune receptors, human leukocyte antigen (HLA) receptor (TCR), complementary antigenic peptide is required for development of DHRs. These idiosyncratic interactions elicited formation drug-protein adducts (hapten...

10.4103/ds.ds-d-23-00082 article EN cc-by-nc-sa Dermatologica Sinica 2023-10-01

In Taiwan, infective native aortic aneurysms (INAAs) are relatively common, so the aim of present study was to demonstrate comparative outcomes endovascular repair for thoracic and abdominal INAAs.

10.1253/circj.cj-23-0146 article EN Circulation Journal 2023-08-28

10.1253/circj.cj-88-content3 article Circulation Journal 2024-02-21

Neuropsychiatric systemic lupus erythematous (NPSLE) encompasses various psychiatric and neurological manifestations that develop in patients with (SLE), secondary to the involvement of central nervous system (CNS). Although neuropsychiatric are commonly described NPSLE, catatonia has been less frequently reported SLE. The roles benzodiazepines (BZDs), immunosuppression, therapeutic plasma exchange (TPE), electroconvulsive therapy (ECT) have all management catatonia. Furthermore, another...

10.3390/jcm11226670 article EN Journal of Clinical Medicine 2022-11-10

Kimura disease (KD) is a rare, chronic proliferative condition presenting as subcutaneous mass predominantly located in the head and neck region; it characterized by eosinophilia elevated serum IgE levels. IgG4-related (IgG4RD) fibroinflammatory swelling single or multiple organs infiltration of IgG4 plasma cells. Herein, we presented two cases. Case 1 38-year-old man with painless his right postauricular region, 2 36-year-old lymphadenopathy bilateral region. After surgical excision, they...

10.3390/jcm11236887 article EN Journal of Clinical Medicine 2022-11-22

Abstract Cancer cachexia is a multifactorial syndrome entailing muscle and fat wasting, inflammation, metabolic dysfunction. Pancreatic cancer has the highest incidence of at around 80%. However, there are no FDA approved therapy for in clinic yet. This mostly because failure preclinical therapies to demonstrate success clinic. Most studies utilize 6-8 week old mice which roughly corresponds human age ~ 20 years. median diagnosis pancreatic ~70 Given widespread physiology, microenvironment,...

10.1158/1538-7445.am2023-356 article EN Cancer Research 2023-04-04

Abstract Objectives: To scrutinize clinical attributes and associated factors of elevated serum IgG4 concentrations over an 8-year timeline in 166 patients diagnosed with IgG4-related diseases (IgG4-RD). Methods : This study conducted retrospective analysis medical records belonging to 2,968 adults, all whom had participated assessments between December 2007 August 2014. Results: Among the participants, we identified (5.6%) having IgG4-RD, while remaining 2,802 (94.4%) were other diseases;...

10.21203/rs.3.rs-3721174/v1 preprint EN cc-by Research Square (Research Square) 2023-12-29
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