- Systemic Lupus Erythematosus Research
- Systemic Sclerosis and Related Diseases
- Folate and B Vitamins Research
- Acne and Rosacea Treatments and Effects
- Platelet Disorders and Treatments
- Atherosclerosis and Cardiovascular Diseases
- Porphyrin Metabolism and Disorders
- Autoimmune Bullous Skin Diseases
- Immunodeficiency and Autoimmune Disorders
University of Calabar
2022-2025
Although there is an increase in prevalence and incidence of lupus worldwide, the journey to diagnosis unduly delayed. This delay associated with worse outcomes. Sub-Saharan Africa has witnessed recent decades no specific data on time lupus. We measured documented diagnostic delays, patients' experiences, factors delayed provided recommendations for early diagnosis. a three-month cross-sectional study 245 patients diagnosed who are members Nigerian support group. Included participants fill...
Abstract Background Systemic lupus erythematosus (SLE) is a chronic multisystemic autoimmune disorder with wide array of clinical manifestations. Lymphadenopathy occasionally observed in patients SLE, and although it sometimes feature active disease, rarely the initial presenting at time diagnosis. Case presentation We report case 35-year-old woman features generalized lymphadenopathy, fatigue, fever, malaise approximately 3 months duration no other constitutional disorders or systemic...
Background: Haematological manifestations are common in SLE, but cytopenias rarely the only abnormality at diagnosis. Case Summary: We report case of a 40-year-old woman who was admitted for recurrent anaemia with 2-month history constitutional symptoms and no other complaints. Her Full Blood Count (FBC) showed bi-cytopenia, Haemoglobin level 4g/dl platelet 77x103/μl. An Autoimmune serology revealed positive Antinuclear antibody (ANA) test 1:2560 SLE antibodies. The diagnosis established...
<p>Cutaneous hyperpigmentation and glossitis are recognized but often overlooked early signs of vitamin B12 deficiency (VB12D). Pernicious anaemia is the most common cause VB12D. Many clinicians miss diagnosis this potentially fatal treatable condition in absence more reported life-threatening neuropsychiatric haematologic features, notwithstanding concomitant presence characteristic cutaneous signs. These apperceptions conspicuous dermatologic lead to diagnostic delay, which can...