A5097928019- RNA Research and Splicing
- RNA and protein synthesis mechanisms
- Bacterial Genetics and Biotechnology
- DNA and Nucleic Acid Chemistry
Stony Brook University
2024
Ribonucleic acid (RNA) molecules can adopt a variety of secondary and tertiary structures in solution, with stem-loops being one the more common motifs. Here, we present systematic analysis 15 RNA stem-loop sequences simulated molecular dynamics simulations an implicit solvent environment. Analysis cluster ensembles showed that generally A-form stem region. Loop are sensitive, experimental could only be reproduced modification CH···O interactions force field, combined nonpolar correction to...
Ribonucleic acid (RNA) molecules can adopt a variety of secondary and tertiary structures in solution, with stem-loops being one the more common motifs. Here we present systematic analysis fifteen RNA stem-loop sequences simulated molecular dynamics simulations an implicit solvent environment. Analysis cluster ensembles showed that generally A-form stem region. Loop are sensitive experimental could only be reproduced modification CH---O interactions force field, combined nonpolar correction...