A5022754923- PARP inhibition in cancer therapy
- Ovarian cancer diagnosis and treatment
- Advanced Breast Cancer Therapies
- Cancer Genomics and Diagnostics
- Advanced Photonic Communication Systems
- Software-Defined Networks and 5G
- Neuropeptides and Animal Physiology
- Beetle Biology and Toxicology Studies
- Biosimilars and Bioanalytical Methods
- Pain Mechanisms and Treatments
- Phytochemical compounds biological activities
- Toxin Mechanisms and Immunotoxins
- Pain Management and Opioid Use
- Advanced Optical Network Technologies
- PI3K/AKT/mTOR signaling in cancer
Tianjin Medical University Cancer Institute and Hospital
2014-2023
Chunghwa Telecom (Taiwan)
2023
This study evaluated maintenance treatment with niraparib, a potent inhibitor of poly(ADP-ribose) polymerase 1/2, in patients platinum-sensitive recurrent ovarian cancer.In this phase III, double-blind, placebo-controlled conducted at 30 centers China, adults cancer who had responded to their most recent platinum-containing chemotherapy were randomized 2 : 1 receive oral niraparib (300 mg/day) or matched placebo until disease progression unacceptable toxicity (NCT03705156). Following...
nude mice, as a model of human ovarian cancer, were used to test the effects PTEN and KRT10 on cisplatin resistance cancer in vivo.The MTT assay showed that recombinant adenovirus-mediated overexpression enhanced proliferation inhibition effect C13K cells.Recombinant adenovirusmediated also increased cisplatin-induced apoptosis rate cells.Furthermore, inhibitory xenograft tumor growth.Thus, may improve vitro vivo.
Service-Based Architecture (SBA) serves as a foundational methodology for 5G core networks, delineated by the 3rd Generation Partnership Project (3GPP). This modular approach segments Core Network into discrete, functionally autonomous Functions (NFs), deployed via either virtual machines or container technologies. The efficacy of SBA execution platform significantly impacts service capabilities these NFs. In this study, we present an enhanced architecture that employs extended Berkeley...