A5012215604- Neonatal and fetal brain pathology
- Neonatal Health and Biochemistry
- Renal Diseases and Glomerulopathies
- Immunodeficiency and Autoimmune Disorders
- COVID-19 Clinical Research Studies
- Neonatal Respiratory Health Research
- Traumatic Brain Injury and Neurovascular Disturbances
- Pediatric Pain Management Techniques
- Adolescent and Pediatric Healthcare
- COVID-19 Impact on Reproduction
- SARS-CoV-2 and COVID-19 Research
Istituto Giannina Gaslini
2020-2025
Background and purpose: Perforator stroke (PS) is a subtype of perinatal arterial ischemic (PAIS), in which injuries occur the territory perforator branches main cerebral arteries. This study aims to explore incidence, timing, risk factors, clinical presentation PS both preterm full-term neonates. Material methods: We retrospectively analyzed data about all neonatal brain MRIs carried out our hospital from March 2012 2023. Criterium inclusion was radiologically confirmed diagnosis involving...
Background: The diagnosis of hemodynamically significant patent ductus arteriosus (hsPDA) occurs in 55% very low birth weight (VLBW) preterm infants. There is no agreement on the best approach to ensure a quick hsPDA closure. Drug treatment fails approximately 20% cases with an increasing risk prolonged ventilation, BPD, and NEC, as well need for surgical duct ligation. This study aims highlight efficacy ibuprofen versus acetaminophen case second cycle medical therapy after failure first...
Haemoglobin levels assessment is a crucial part of neonatal intensive care practice, the painful experience repeated heel pricks and venepunctures blood sampling may negatively affect clinical course. To date reliability haemoglobin obtained by point-of-care testing (POCT) analysis if compared to standard cell count remains controversial. Retrospective study conducted on all inborn premature infants (gestational age < 32 weeks) admitted NICU IRCCS Giannina Gaslini Institute during period May...
Thirty years ago, the first attempt by Saliba and colleagues was made to reduce negative effects (hypercarbia) of exogenous surfactant (ES) slowing its administration. Sixteen later, we observed less invasive administration (LISA) Kribs colleagues. Many studies, since that time, have tried minimize invasiveness ES subsequent cerebral blood flow perturbations through studies using near-infrared spectroscopy (NIRS). We sought address this medical challenge identifying a problematic modality...