Akshata Hegde

ORCID: 0009-0009-7077-9420
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About
Contact & Profiles
Research Areas
  • Glioma Diagnosis and Treatment
  • Meningioma and schwannoma management
  • Genetic and phenotypic traits in livestock
  • Genetic Mapping and Diversity in Plants and Animals
  • Reproductive Biology and Fertility
  • Bone Tumor Diagnosis and Treatments
  • Head and Neck Surgical Oncology
  • Pituitary Gland Disorders and Treatments
  • Neurofibromatosis and Schwannoma Cases
  • Cancer-related Molecular Pathways
  • Neuroblastoma Research and Treatments
  • Cerebrospinal fluid and hydrocephalus
  • Medical Imaging and Pathology Studies
  • Neurosurgical Procedures and Complications
  • Brain Metastases and Treatment
  • Cardiac tumors and thrombi
  • Autophagy in Disease and Therapy
  • Biosensors and Analytical Detection
  • Intracranial Aneurysms: Treatment and Complications
  • Virus-based gene therapy research
  • Vascular Malformations Diagnosis and Treatment
  • Cancer Cells and Metastasis
  • Histiocytic Disorders and Treatments
  • Fetal and Pediatric Neurological Disorders
  • Bioinformatics and Genomic Networks

University of Missouri
2024

University of Missouri Health System
2024

Liverpool Hospital
2017

Western Sydney University
2017

M.S. Ramaiah Medical College
2017

Sri Sathya Sai Institute of Higher Medical Sciences
2004-2011

Sri Sathya Sai Institute of Higher Medical Sciences
2009-2011

Jaslok Hospital
2005

Shinshu University
1989

The oviduct is the site of fertilization and preimplantation embryo development in mammals. Evidence suggests that gametes alter oviductal gene expression. To delineate adaptive interactions between gamete/embryo, we performed a multi-omics characterization tissues utilizing bulk RNA-sequencing (RNA-seq), single-cell (scRNA-seq), proteomics collected from distal proximal at various stages after mating mice. We observed robust region-specific transcriptional signatures. Specifically, presence...

10.7554/elife.100705.2 preprint EN 2025-02-13

Pigs are playing an increasingly vital role as translational biomedical models for studying human pathophysiology. The annotation of the pig genome was a huge step forward in translatability pigs model various diseases. Similarities between humans and terms anatomy, physiology, genetics, immunology have allowed to become comprehensive preclinical With diverse range, from craniofacial ophthalmology reproduction, wound healing, musculoskeletal, cancer, provided seminal understanding This...

10.14740/wjon1763 article EN World Journal of Oncology 2024-03-21

Abstract Motivation: Gene Regulatory Networks (GRNs) are crucial for understanding cellular processes, but accurately inferring them from gene expression data remains challenging due to the complex, non-linear interactions between genes and high dimensionality of data. We introduce GRN-Former, an advanced graph transformer model designed infer regulatory relationships transcription factors target single-cell RNA-seq transcriptomics data, while supporting generalization across species cell...

10.1101/2025.01.26.634966 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2025-01-27

ABSTRACT The oviduct is the site of fertilization and preimplantation embryo development in mammals. Evidence suggests that gametes alter oviductal gene expression. To delineate adaptive interactions between gamete/embryo, we performed a multi-omics characterization tissues utilizing bulk RNA-sequencing (RNA-seq), single-cell (scRNA-seq), proteomics collected from distal proximal at various stages after mating mice. We observed robust region-specific transcriptional signatures. Specifically,...

10.1101/2024.06.13.598905 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2024-06-15

Abstract A cytohistological correlation with determination of accuracy rate smear preparation result was done in a retrospective study 306 cases intracranial tumors. Cytomorphology few new entities CNS tumors are described. The cytological features and WHO grading the were described on preparation. discrepancy histological diagnosis reviewed again final possible which should have been given is discussed. clinical details like age, sex, site analyzed. age range patients from 3 years to 63...

10.1002/dc.21432 article EN Diagnostic Cytopathology 2010-11-09

The oviduct is the site of fertilization and preimplantation embryo development in mammals. Evidence suggests that gametes alter oviductal gene expression. To delineate adaptive interactions between gamete/embryo, we performed a multi-omics characterization tissues utilizing bulk RNA-sequencing (RNA-seq), single-cell (scRNA-seq), proteomics collected from distal proximal at various stages after mating mice. We observed robust region-specific transcriptional signatures. Specifically, presence...

10.7554/elife.100705.1 preprint EN 2024-10-01

The widespread use of pesticides in agriculture poses food safety and environmental risks, highlighting the need for rapid detection techniques to mitigate contamination. Surface-enhanced Raman spectroscopy (SERS) coupled with machine learning provides a powerful approach quantification multiple agricultural products. This study introduces SERSFormer-2.0 model, which excels both multilabel classification multiregression tasks pesticide analysis, leveraging power transformer-based...

10.1021/acsami.4c17777 article EN ACS Applied Materials & Interfaces 2024-12-20

Abstract We report a rare case of recurrent chordoid glioma in suprasellar region with extension into the third ventricle diagnosed peroperatively. On MRI, brilliantly contrast enhancing lesion extending superiorly and measuring 2.5 × 3 3.5 cm was identified. Patient had previous history subtotal removal tumor 8 months back received 56 Gy postoperative radiotherapy. smear preparation composed cells arranged chords rows myxoid background sprinkling lymphocytes. The individual were polygonal...

10.1002/dc.21606 article EN Diagnostic Cytopathology 2011-02-13

10.4103/0971-3026.29185 article IT Indian journal of radiology and imaging - new series/Indian journal of radiology and imaging/Indian Journal of Radiology & Imaging 2005-01-01
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