A5000351539- Pharmaceutical and Antibiotic Environmental Impacts
- Reproductive biology and impacts on aquatic species
- Physiological and biochemical adaptations
- Fish Ecology and Management Studies
- Environmental Toxicology and Ecotoxicology
- Aquaculture Nutrition and Growth
- Estrogen and related hormone effects
- Effects and risks of endocrine disrupting chemicals
- Reproductive System and Pregnancy
- Sperm and Testicular Function
- Synthesis and pharmacology of benzodiazepine derivatives
- bioluminescence and chemiluminescence research
- Inflammatory mediators and NSAID effects
McMaster University
2018-2025
Chronic low-concentration chemical exposures may have both direct health outcomes on adults and indirect effects their offspring. Using zebrafish, we examined the impacts of chronic, carbamazepine (CBZ) exposure a suite male reproductive endpoints in parents four generations offspring reared clean water. CBZ is one most frequently detected pharmaceutical residues water, histone deacetylase inhibitor mammals, reported to lower androgens mammals fish. Exposure adult zebrafish 10 μg/L for 6...
Early life development in fishes is a period of high phenotypic plasticity. Water temperatures during embryogenesis can lead to alterations growth and metabolic morphological variations. This study aimed characterize the effects temperature on morphology yellow perch throughout early development, species significant ecological economic importance North America. Yellow (Perca flavescens) embryos were incubated at either constant (12, 15, or 18°C) under an ambient seasonal regime, where...
The effects of parental exposure to pharmaceuticals on sexual differentiation in F1 offspring were examined zebrafish (Danio rerio). Adult exposed 0 or 10 μg/L carbamazepine gemfibrozil for 6 wk and bred pairwise crosses generate 7 distinct lineages. Lineages formed with both parents from the same treatment group only one parent exposed, delineate between maternal paternal effects. each lineage reared clean water sampled at 45 60 d post fertilization (dpf). Gonadal was assessed by histology....
Abstract The ontogenetic development in teleost fish is sensitive to temperature, and the developmental rate has a direct relationship with environmental temperature within species' thermal tolerance limit. Temperature determines time survival at hatching. Yellow perch North American species of ecological commercial importance, its phenology vulnerable climate change. embryonic yellow was comparable closely related members family Percidae. Developmental progression fastest 18°C slowest 12°C,...
Temperate waters, such as the Great Lakes, are predicted to increase by 1{degree sign}C every decade. Poikilothermic fish thermoregulate behaviourally, moving more suitable thermal environments. Embryos incapable of locomotion and may be exposed non-optimal temperatures during development. Increased temperature alters normal development yellow perch (Perca flavescens), however, whether altered incubation influences metabolism function in these remains unknown. We hypothesized that increased...