Federica Neve Vigotti
A5010626905- Dialysis and Renal Disease Management
- Pregnancy and preeclampsia studies
- Renal Transplantation Outcomes and Treatments
- Chronic Kidney Disease and Diabetes
- Pregnancy and Medication Impact
- Diet and metabolism studies
- Parathyroid Disorders and Treatments
- Health Systems, Economic Evaluations, Quality of Life
- SARS-CoV-2 and COVID-19 Research
- Pharmacological Effects and Toxicity Studies
- Renal and Vascular Pathologies
- Metabolism and Genetic Disorders
- Renal Diseases and Glomerulopathies
- COVID-19 Clinical Research Studies
- Electrolyte and hormonal disorders
- Nutritional Studies and Diet
- Kidney Stones and Urolithiasis Treatments
- Systemic Sclerosis and Related Diseases
- Prenatal Screening and Diagnostics
- Heart Failure Treatment and Management
- Organ Transplantation Techniques and Outcomes
- Acute Kidney Injury Research
- Hemodynamic Monitoring and Therapy
- Frailty in Older Adults
- Blood Pressure and Hypertension Studies
Ospedale Martini
2021-2024
University of Turin
2011-2019
Ospedale Civile Edoardo Agnelli
2018
CTO Hospital
2017
Ospedale San Luigi Gonzaga
2011-2015
Gonzaga University
2015
Azienda Ospedaliero Universitaria San Giovanni Battista
2005
CKD is increasingly prevalent in pregnancy. In the Torino-Cagliari Observational Study (TOCOS), we assessed whether risk for adverse pregnancy outcomes associated with by comparing of 504 pregnancies women to 836 low-risk without CKD. The presence hypertension, proteinuria (>1 g/d), systemic disease, and stage (at referral) were at baseline. following studied: cesarean section, preterm delivery, early delivery; small gestational age (SGA); need neonatal intensive care unit (NICU); new...
Background People with reduced glomerular filtration rate (GFR) often have elevated cardiac troponin T (cTnT) levels. It remains unclear how cTnT levels develop over time in those chronic kidney disease (CKD). The aim of this study was to prospectively the association between and GFR older advanced‐stage CKD patients not on dialysis. Methods Results EQUAL (European Quality Study) is an observational prospective cohort stage 4 5 aged ≥65 years dialysis (incident estimated GFR, <20...
Chronic kidney disease (CKD) is increasingly encountered in pregnancy because of greater diagnostic awareness, which a reflection the newer, broader definitions (i.e., any changes blood or urine composition at imaging, glomerular filtration rate (GFR) <60 mL/min lasting least 3 months) and increased incidence (higher maternal age better outcomes several diseases). CKD extremely heterogeneous may be described by degree GFR reduction (CKD stages), presence proteinuria hypertension type...
Patients with chronic kidney disease (CKD) are at a higher risk of major adverse cardiovascular events (MACE) compared the general population, but gender differences in this risk, especially older adults, not fully known. We aim to identify MACE European CKD patients, and explore factors that may explain these differences.The Quality study (EQUAL) is prospective on stage 4-5 ≥65 years old, dialysis, from Germany, Italy, Netherlands, Poland, Sweden UK. Cox regression cumulative incidence...
Concerns about adherence and quality of life (QoL) limit the diffusion low-protein diets (LPDs) as a way to slow chronic kidney disease (CKD) progression postpone dialysis. The aim this multicentre study is assess dietary satisfaction in stable CKD patients.This was cross-sectional with long-term follow-up data. Prevalent patients on LPD for at least 6 months were selected four Italian centres. QoL assessed using World Health Organization Quality Life questionnaire, diet Modification Diet...
MELAS syndrome (MIM ID#540000), an acronym for Mitochondrial Encephalopathy, Lactic Acidosis and Stroke-like episodes, is a genetically heterogeneous mitochondrial disorder with protean manifestations occasional kidney involvement. Interest in the latter rising due to identification of cases predominant involvement hypothesis link between DNA neoplasia.We report case 41-year-old male full blown syndrome, lactic acidosis neurological impairment, affected by "classic" 3243A > G mutation DNA,...
There is no single, gold-standard, low-protein diet (LPD) for CKD patients; the best compliance probably obtained by personalization. This study tests hypothesis that a multiple choice network allows patients to attain good level, and that, in an open-choice system, overall results are not dependent upon specific diet, but clinical characteristics of patients. Observational study: Three LPD options were offered all with severe or rapidly progressive CKD: vegan diets supplemented...
The correlation between advanced or proteinuric chronic kidney disease (CKD) and adverse pregnancy outcomes is intuitive, although how early CKD affects remains unknown. Glomerular hyperfiltration a physiological response to pregnancy, correlated with in hypertension collagen diseases. aim of the study was correlate first trimester stage 1 patients.A historical prospective conducted on database our Unit, gathering all pregnant patients referred since January 2000. From 383 pregnancies...
Low-protein diets (LPDs) are often considered as contraindicated in diabetic patients, and seldom studied. The aim of this observational study was to provide new data on issue. It involved 149 300 non-diabetic patients who followed a LPD, with personalized approach aimed at moderate protein restriction (0.6 g/day). Survival analysis performed according Kaplan–Meier, multivariate Cox model. Diabetic versus were similar age (median 70 years) creatinine levels the start diet (2.78 mg/dL vs....
The indications for delaying the start of dialysis have revived interest in low-protein diets (LPDs). In this observational prospective study, we enrolled all patients with chronic kidney disease (CKD) who followed a moderately restricted LPD 2007–2015 nephrology unit Italy: 449 patients, 847 years observation. At diet, median glomerular filtration rate (GFR) was 20 mL/min, age 70, Charlson Index 7. Standardized mortality rates “on-diet” population were significantly lower than on (United...
ABSTRACT Background We explore longitudinal trajectories of clinical indicators, patient-reported outcomes, and hospitalizations, in the years preceding death a population older patients with advanced chronic kidney disease (CKD). Methods The EQUAL study is European observational prospective cohort an incident eGFR &lt;20 ml/min per 1.73 m2 ≥65 age. evolution each indicator was explored using generalized additive models during 4 death. Results included 661 decedents median time to 2.0...
Background. There is an increasing tendency to allocate kidneys from marginal donors in older recipients. This combination optimizes the uses of expanded donor pool but demands attention for higher nephrotoxic sensitivity kidney and increased immunosuppression vulnerability elderly We aimed reduce these hazards by means a calcineurin-free induction therapy followed maintenance regimen targeted minimize/withdraw steroid. Methods. Eighty-eight single (43%) or double (57%) transplant recipients...
Patients with stage 4/5 chronic kidney disease (CKD) suffer from various symptoms. The retention of uremic solutes is thought to be associated those However, there are relatively few rigorous studies on the potential links between toxins and symptoms in patients CKD.The EQUAL study an ongoing observational cohort non-dialyzed CKD. Germany, Poland, Sweden UK were included present (n = 795). Data symptom self-report questionnaires collected April 2012 September 2020. Baseline uric acid...
Predicting the timing and occurrence of kidney replacement therapy (KRT), cardiovascular events, death among patients with advanced chronic disease (CKD) is clinically useful relevant. We aimed to externally validate a recently developed CKD G4+ risk calculator for these outcomes assess its potential clinical impact in guiding vascular access placement.We included 1517 from European Quality (EQUAL) study, multicentre prospective cohort study nephrology-referred aged ≥65 years. Model...
Diabetes and nephropathy are important challenges during pregnancy, increasingly encountered because of the advances in maternal-fetal care.To evaluate maternal fetal outcomes recorded "severe" diabetic type 1 patients referred to nephrological healtcare.The study was performed an outpatient unit dedicated kidney diseases pregnancy (with joint obstetric follow-up strict cooperation with diabetes unit). 383 pregnancies were 2000-2012, 14 which complicated by diabetes. The report includes 12...
Renal function recovery (RFR), defined as the discontinuation of dialysis after 3 months replacement therapy, is reported in about 1% chronic patients. The role personalized, intensive schedules and resuming low-protein diets has not been studied to date. This report describes three patients with RFR who were recently treated at a new unit set up offer hemodialysis. All females, aged 73, 75, 78 years. Kidney disease included vascular-cholesterol emboli, diabetic nephropathy vascular...
We report on a so-far never described association between glomerulonephritis and sarcoid-like lung disease after long-term interferon beta (IFNb) treatment for relapsing–remitting multiple sclerosis. The interest in this case resides the documented remission IFNb discontinuation. history of IFNb-related adverse events is probably not yet completely written. rapid reversal pathological signs our patient underlines importance careful clinical laboratory surveillance, including kidney...
Depressive symptoms are associated with adverse clinical outcomes in patients end-stage kidney disease; however, few small studies have examined this association earlier phases of chronic disease (CKD). We studied associations between baseline depressive and older advanced CKD whether these differed depending on sex.CKD (≥65 years; estimated glomerular filtration rate ≤20 mL/min/1.73 m2) were included from a European multicentre prospective cohort 2012 2019. measured by the five-item Mental...