A5079354898- Intracranial Aneurysms: Treatment and Complications
- Traumatic Brain Injury and Neurovascular Disturbances
- Cardiac Arrest and Resuscitation
- Thermal Regulation in Medicine
- Antiplatelet Therapy and Cardiovascular Diseases
- Neurosurgical Procedures and Complications
- Cardiac and Coronary Surgery Techniques
- S100 Proteins and Annexins
- Cerebrovascular and Carotid Artery Diseases
- Vascular Malformations Diagnosis and Treatment
- Platelet Disorders and Treatments
University of Edinburgh
2015-2023
Western General Hospital
2016
Traumatic brain injury (TBI) is a significant cause of disability and death huge economic burden throughout the world. Much morbidity associated with TBI attributed to secondary injuries resulting in hypoxia ischemia after initial trauma. Intracranial hypertension decreased partial oxygen tension (PbtO2) are targeted as potentially avoidable causes morbidity. Therapeutic hypothermia (TH) may be an effective intervention reduce intracranial pressure (ICP), but could also affect cerebral blood...
Delayed cerebral ischaemia has been described as the single most important cause of morbidity and mortality in patients who survive initial aneurysmal subarachnoid haemorrhage. Our understanding pathophysiology delayed is meagre at best calcium channel blocker nimodipine remains only intervention to consistently improve functional outcome after There substantial evidence support vessel narrowing a causative factor ischaemia, but contemporary research demonstrating improvements failed show...
Dual antiplatelet therapy (DAPT) is standard care for intracranial stenting to prevent thrombotic complications. Clopidogrel resistance has resulted in patients receiving newer P2Y12 inhibitors like Prasugrel, which may reduce complications but could increase haemorrhagic This study, utilising platelet reactivity testing, compared and associated with or 20 mg Prasugrel loading treated flow diverters (FD) aneurysms.We retrospectively analysed prospectively collected data from 225 consecutive...