A5078460930- Radiation Therapy and Dosimetry
- Dermatologic Treatments and Research
- Cancer, Hypoxia, and Metabolism
- Erythrocyte Function and Pathophysiology
- Hair Growth and Disorders
- Facial Rejuvenation and Surgery Techniques
- Nanopore and Nanochannel Transport Studies
- Hemoglobin structure and function
- Nanoparticle-Based Drug Delivery
Chinese Academy of Medical Sciences & Peking Union Medical College
2023-2025
Sichuan University
2025
West China Hospital of Sichuan University
2025
Liposome, a widely used drug delivery system (DDS), still shows several disadvantages such as dominant clearance by liver and poor target organ deposition. To overcome the drawbacks of liposomes, we developed novel red blood cell (RBC)-liposome combined DDS to modulate tumor accumulation extend circulation life existing liposomal DDS. Here, RBCs, an ideal natural carrier DDS, were utilized carry liposomes avoid them undergo fast in blood. In this study, could either absorbed onto RBCs'...
Radiotherapy (RT) is a highly valuable method in cancer therapy, but its therapeutic efficacy limited by side effects and tumour radiation resistance. The resistance mainly induced hypoxia the microenvironment (TME). As nano-oxygen carrier, Haemoglobin-based oxygen carriers (HBOCs) administration promising strategy to alleviate which may remodel TME ameliorate enable RT more effective. In this study, we administered fractionated combined with HBOC treat Miapaca-2 cell Hela xenografts on nude...