Genomic Surveillance for SARS-CoV-2 Variants of Concern from Imported COVID-19 Cases - the Mainland of China, 2021.

• DOI: 10.46234/ccdcw2022.144
• Publication Date: 2022-08-05
• Authors: Yenan Feng; Xiang Zhao; Zhixiao Chen; Kai Nie; Zeyuan Yin; Ying Xia; Ji Wang; Peihua Niu; A Ruhan; Lili Li; Dayan Wang; Wenjie Tan; Xuejun Ma; Shiwen Wang; Huanyu Wang; George F. Gao; Cao Chen; Wenbo Xu
• Keywords: 2019-20 coronavirus outbreak; Highly pathogenic

After the epidemic in Wuhan City was brought under control 2020, local outbreaks of coronavirus disease 2019 (COVID-19) mainland China were mainly due to imported COVID-19 cases. The ongoing evolution severe acute respiratory syndrome 2 (SARS-CoV-2) has continued generate new variants. Some have been designated as variants concern (VOCs) by World Health Organization (WHO). To better assess role SARS-CoV-2 surveillance and prevalence VOCs 2021, genomic data from cases 2021 analyzed.The analyses included number sequence submissions, time deposition, detection order determine timeliness sensitivity surveillance. proportions analyzed compared with Global Initiative Sharing All Influenza Data (GISAID).A total 3,355 sequences submitted 29 provincial-level administrative divisions, differences submissions median deposition. A 2,388 more than 90% coverage used for lineage analysis. trend Alpha Delta Omicron consistent that GISAID. In addition, usually identified after WHO designation before causing outbreaks.The global distribution changed rapidly 2021. Robust is great significance.