- Neuroscience and Neuropharmacology Research
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Acupuncture Treatment Research Studies
- Neuropeptides and Animal Physiology
- Ion channel regulation and function
- Cancer, Hypoxia, and Metabolism
- Ionosphere and magnetosphere dynamics
- Pharmacological Receptor Mechanisms and Effects
- Earthquake Detection and Analysis
- Seismic Waves and Analysis
- Mesenchymal stem cell research
- Parkinson's Disease Mechanisms and Treatments
- Neuroinflammation and Neurodegeneration Mechanisms
- Eicosanoids and Hypertension Pharmacology
- Pain Mechanisms and Treatments
- Cardiac Ischemia and Reperfusion
- Neuroscience of respiration and sleep
- MicroRNA in disease regulation
- Cancer Cells and Metastasis
- Cancer, Stress, Anesthesia, and Immune Response
- Nerve injury and regeneration
- Water Treatment and Disinfection
- Healthcare and Venom Research
- Adipose Tissue and Metabolism
Fudan University
2008-2025
Hainan Provincial Hospital of Traditional Chinese Medicine
2025
Shanghai Research Center for Acupuncture and Meridians
2008-2025
Jilin University
2021-2025
First Hospital of Jilin University
2021-2025
Zhejiang University of Technology
2025
Hainan University
2025
China National Petroleum Corporation (China)
2025
Hubei University of Science and Technology
2025
Nanjing Tech University
2007-2025
Adipose-derived stem cells (ADSCs) have been shown to induce wound-healing effects. Because inflammation near the wound area induces oxygen deficiency, it is interesting elucidate effect of hypoxia on function ADSCs. In this work, we asked: (1) does alter ADSCs? and (2) what are major factors responsible for alteration in function? Effect proliferation ADSCs was first examined that (2% O(2)) enhanced either presence serum or absence serum. The conditioned medium harvested under (hypoCM)...
We previously described a mouse model of fibrotic ischemia/reperfusion cardiomyopathy (I/RC) arising from daily, brief coronary occlusion. One characteristic I/RC was the prolonged elevation monocyte chemoattractant protein 1 (MCP-1), which obligate to its phenotype and may contribute uptake bloodborne cells. Here we describe in hearts population small spindle-shaped fibroblasts that were highly proliferative expressed collagen I α-smooth muscle actin (myofibroblast markers), CD34 (a...
Cellular cardiomyoplasty is an attractive option for the treatment of severe heart failure. It is, however, still unclear and controversial which most promising cell source. Therefore, we investigated examined fate functional impact bone marrow (BM) cells embryonic stem (ES cell)–derived cardiomyocytes after transplantation into infarcted mouse heart. This proved particularly challenging ES cells, as their enrichment long-term engraftment tumorigenicity are poorly understood. We generated...
For improving the capability, cycling stability and rate capacity of anatase TiO2-based electrode, Mo-doped TiO2 encapsulated in nitrogen-doped amorphous carbon (denoted for Mo-TiO2@NC) were synthesized through a facile hydrothermal method followed by coating with polyaniline (PANI) heating treatment. When tested as anode lithium ion batteries, Mo-TiO2@NC electrode showed initial discharge charge capacities 850.7 548.3 mAh g-1 at current density 85 mA g-1, respectively, remarkable maintained...
Abstract Electrocatalytic reduction of carbon dioxide (CO 2 ER) in rechargeable Zn–CO battery still remains a great challenge. Herein, highly efficient CO ER electrocatalyst composed coordinatively unsaturated single‐atom copper coordinated with nitrogen sites anchored into graphene matrix (Cu–N /GN) is reported. Benefitting from the coordination environment and atomic dispersion, ultrathin Cu–N /GN nanosheets exhibit high activity selectivity for production an onset potential −0.33 V...
Abstract Electrochemically driven carbon dioxide (CO 2 ) conversion is an emerging research field due to the global warming and energy crisis. Carbon monoxide (CO) one key product during electroreduction of CO ; however, this reduction process suffers from tardy kinetics low local concentration on a catalyst's surface density active sites. Herein, presented combination experimental theoretical validation Ni porphyrin‐based covalent triazine framework (NiPor‐CTF) with atomically dispersed NiN...
Abstract Development of inexpensive and efficient oxygen evolution reaction (OER) catalysts in acidic environment is very challenging, but it important for practical proton exchange membrane water electrolyzers. A molecular iron–nitrogen coordinated carbon nanofiber developed, which supported on an electrochemically exfoliated graphene (FeN 4 /NF/EG) electrocatalyst through carbonizing the precursor composed iron ions absorbed polyaniline‐electrodeposited EG. Benefitting from unique 3D...
Abstract Cancer, a complex and multifactorial disease, presents significant challenge to global health. Despite advances in surgical, radiotherapeutic immunological approaches, which have improved cancer treatment outcomes, drug therapy continues serve as key therapeutic strategy. However, the clinical efficacy of is often constrained by resistance severe toxic side effects, thus there remains critical need develop novel therapeutics. One promising strategy that has received widespread...
Mitochondria-associated ferroptosis exacerbates cardiac microvascular dysfunction in diabetic cardiomyopathy (DCM). Nicorandil, an ATP-sensitive K+ channel opener, protects against endothelial dysfunction, mitochondrial and DCM; however, its effects on mitophagy remain unexplored. The present study aimed to assess the beneficial of nicorandil DCM underlying mechanisms. Cardiac perfusion was assessed using a lectin assay, while via mt-Keima transfection transmission electron microscopy....
The therapeutical potential of transplantation undifferentiated and predifferentiated murine embryonic stem cells for the regeneration injured brain was investigated in two rodent stroke models. Undifferentiated xenotransplanted into rat at hemisphere opposite to ischemic injury migrated along corpus callosum towards damaged tissue differentiated neurons border zone lesion. In homologous mouse brain, same did not migrate, but produced highly malignant teratocarcinomas site implantation,...
Cardiac interstitial fibrosis plays an important role in the pathogenesis of ischemic cardiomyopathy, contributing to systolic and diastolic dysfunction. We have recently developed a mouse model fibrotic noninfarctive cardiomyopathy due brief repetitive myocardial ischemia reperfusion. In this model, changes are preceded by marked selective induction CC chemokine monocyte chemoattractant protein-1 (MCP-1). hypothesized that MCP-1 may mediate remodeling through recruitment mononuclear cells...
The distribution and postnatal ontogeny of opioid receptors have been investigated using in vitro quantitative receptor autoradiography. Rats were studied at day 1 (P1), P5, P10, P21 P120 (adult). Opioid sites for (D-Ala2,N-MePhe4,Gly-ol5)-enkephalin (DAMGO) binding labelled with 4 nM 3H-DAMGO; (D-Ala2,D-Leu5)-enkephalin (DADLE) 3H-DADLE the presence microM unlabelled mu-agonist (N-MePhe3,D-Pro4)-morphiceptin (PL107). We found that both strikingly different distributional patterns. [3H]DADLE...
The matricellular protein thrombospondin (TSP) 1 is induced after tissue injury and may regulate reparative responses by activating transforming growth factor-β, suppressing angiogenesis modulating inflammation matrix metabolism. We hypothesized that endogenous TSP-1 be involved in the pathogenesis of cardiac remodeling pressure-overloaded heart. Myocardial expression was increased a mouse model pressure overload because transverse aortic constriction. −/− mice exhibited early hypertrophy...
Mo-doped SnS<sub>2</sub> nanosheets supported on carbon cloth are synthesized. The nanosheets, as additive-free integrated electrodes for LIBs, exhibit a high initial discharge capacity, superior cycling performance and rate capability.
This paper provides a preliminary analysis of the nature Chinese manufacturing investments in Africa, focusing predominantly on four countries – Ethiopia, Ghana, Nigeria, and Tanzania but also including examples as illustrations from other countries, when appropriate. Drawing fieldwork conducted between 2014 2015, explores varieties existing investment sectors into which companies are investing. We demonstrate this that Africa is indeed expanding rapidly, yet official data approvals, both...