Zhixiao Chen

ORCID: 0009-0005-3631-0232
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About
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Research Areas
  • SARS-CoV-2 and COVID-19 Research
  • SARS-CoV-2 detection and testing
  • Advanced Photonic Communication Systems
  • Optical Network Technologies
  • Optical Wireless Communication Technologies
  • Advanced Fiber Laser Technologies
  • COVID-19 Clinical Research Studies
  • Animal Virus Infections Studies
  • Polymer Nanocomposites and Properties
  • Radio Wave Propagation Studies
  • Bacteriophages and microbial interactions
  • COVID-19 diagnosis using AI
  • Fiber-reinforced polymer composites
  • Infection Control and Ventilation
  • COVID-19 epidemiological studies
  • Gastric Cancer Management and Outcomes
  • Orbital Angular Momentum in Optics
  • Tribology and Wear Analysis
  • Genomics and Rare Diseases
  • Photonic and Optical Devices
  • MicroRNA in disease regulation
  • T-cell and Retrovirus Studies
  • Cancer, Hypoxia, and Metabolism
  • vaccines and immunoinformatics approaches
  • Natural Compounds in Disease Treatment

National Institute for Viral Disease Control and Prevention
2020-2024

Nanjing University of Information Science and Technology
2023-2024

National Health and Family Planning Commission
2022

Shanghai First People's Hospital
2015-2022

Shanghai Jiao Tong University
2019-2022

Chinese Center For Disease Control and Prevention
2022

Xinjiang Uygur Autonomous Region Education Department
2021

State Key Laboratory of Inorganic Synthesis and Preparative Chemistry
2019-2021

Jilin University
2019-2021

Xintai People's Hospital
2021

<abstract abstract-type="Abstract"> <sec> <b>Introduction</b> The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has generated 2,431 variants over the course of its global transmission past 3 years. To better evaluate genomic variation SARS-CoV-2 before and after optimization disease 2019 (COVID-19) prevention control strategies, we analyzed genetic evolution branch composition in both domestic imported cases China (the data from Hong Kong Macau Special Administrativc Regions...

10.46234/ccdcw2023.026 article EN China CDC Weekly 2023-01-01

Colorectal cancer (CRC) is a major health problem in China and around the world. It one of leading causes cancer-related deaths. Research groups are thus searching for novel more efficient anti-CRC agents. Here we demonstrated that ABC294640, SphK2 inhibitor, induced growth inhibition apoptosis transformed primary CRC cells. The SphK activity was remarkably inhibited by accompanied sphingosine-1-phosphate (S1P) depletion ceramide incensement Exogenously-added S1P ABC294640-induced HT-29 cell...

10.1186/s13046-015-0205-y article EN cc-by Journal of Experimental & Clinical Cancer Research 2015-09-03

The technology of speech emotion recognition (SER) has been widely applied in the field human-computer interaction within Internet Vehicles (IoV). incorporation emerging technologies such as artificial intelligence and big data accelerated advancement SER technology. However, this reveals challenges limited computational resources, processing inefficiency, security privacy concerns. In recent years, quantum machine learning to intelligent transportation, which demonstrated its various...

10.1109/tiv.2024.3370398 article EN IEEE Transactions on Intelligent Vehicles 2024-01-01

The M-ary support vector machine (SVM) is introduced as a nonparameter nonlinear phase noise (NLPN) mitigation approach for the coherent optical systems. NLPN tolerance of system can be improved by using SVM to conduct detection. In this scheme, SVMs with different classification strategies are utilized execute binary signals impaired fiber NLPN. Since separating hyperplane each constructed training data, scheme independent from knowledge transmission link. numerical simulation, performs...

10.1109/jphot.2013.2287565 article EN cc-by-nc-nd IEEE photonics journal 2013-11-11

Hsa-miRNA-875-5p (miR-875-5p) has recently been discovered to have anticancer efficacy in different organs. However, the role of miR-875-5p on colorectal carcinoma (CRC) is still ambiguous. In this study, we investigated development CRC. The results indicated that was significantly down-regulated primary tumor tissues and very low levels were found CRC cell lines. Ectopic expression lines suppressed growth as evidenced by viability assay, colony formation assay BrdU staining, through...

10.18632/oncotarget.9944 article EN Oncotarget 2016-06-10

<sec> <b>What is already known about this topic?</b> </sec><sec> Though coronavirus disease 2019 (COVID-19) has largely been controlled in China, several outbreaks of COVID-19 have occurred from importation cases or suspected virus-contaminated products. traced to severe acute respiratory syndrome 2 (SARS-CoV-2) isolated on the outer packaging cold chain products, live virus not obtained. added by report?</b> In September 2020, two dock workers were detected as having asymptomatic SARS-CoV-2...

10.46234/ccdcw2021.164 article EN China CDC Weekly 2021-01-01

In receiver diversity systems, signal replicas will suffer from channel correlations if there are insufficient spacings for component receivers. Knowledge of the correlation is important system performance assessment and improvement. this paper, we give a theoretical study in systems. Based on plane-wave model extended Rytov theory ABCD ray-matrix formulation, expressions derived under general atmospheric conditions. The effects antenna spacing, turbulence strength, aperture size, wavelength...

10.1088/2040-8978/14/12/125710 article EN Journal of Optics 2012-11-13

After 56 days without coronavirus disease 2019 (COVID-19) cases, reemergent cases were reported in Beijing, China on June 11, 2020. Here, we report the genetic characteristics of severe acute respiratory syndrome 2 (SARS-CoV-2) sequenced from clinical specimens 4 human and environmental samples. The nucleotide similarity among six SARS-CoV-2 genomes ranged 99.98% to 99.99%. Compared with reference strain (GenBank No. NC_045512), all genome sequences shared same substitutions at nt241 (C →...

10.1016/j.bsheal.2020.08.006 article EN cc-by-nc-nd Biosafety and Health 2020-09-02

Starting from December 2019, Wuhan, China, encountered the first outbreak of coronavirus disease 2019 (COVID-19) (1-2).The epidemic was successfully suppressed by strict containment so that number infected people reduced to 0 on April 8, 2020 (3-4).After that, China experienced roughly 3 dozen outbreaks with local transmission caused imported severe acute respiratory syndrome 2 (SARS-CoV-2).These were then contained an effective suppression strategy, and has reached zero again.However,...

10.46234/ccdcw2021.213 article EN China CDC Weekly 2021-01-01

<abstract abstract-type="Abstract"> <sec> <b>Introduction</b> In the first half of 2023, a global shift was observed towards predominance XBB variants. China faced significant epidemic between late 2022 and early 2023 due to Omicron subvariants BA.5.2 BF.7. This study aims depict evolving variant distribution among provincial-level administrative divisions (PLADs) in explore factors driving replacement. </sec><sec> <b>Methods</b> Sequences from local imported coronavirus disease 2019...

10.46234/ccdcw2024.061 article EN cc-by Deleted Journal 2024-01-01

The general model of beam wander for a coherent Gaussian propagating through atmospheric turbulence is extended to the case partially polarized electromagnetic Gaussian-Schell (EGSM) beam. expression obtained by characterizing EGSM with effective parameters. effects initial spatially lengths, degree polarization, and phase curvature are examined in detail. A condition derived under which beams different spatial coherence degrees polarization will generate same wander.

10.1364/ao.51.007581 article EN Applied Optics 2012-10-24

Two factors, the crosslinking degree of matrix (ν) and size filler (Sz), have significant impact on Mullins effect filled elastomers. Herein, result. two factors is systematically investigated by adjusting via adding maleic anhydride into a rubber controlling particle ball milling. The dissipation ratios (the ratio energy to input strain energy) different natural rubber/butadiene (NR/BR) elastomer composites are evaluated as function maximum in cyclic loading (εm). show linear relationship...

10.3390/polym13142284 article EN Polymers 2021-07-12

Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is one of the consolidation modalities for adult patients with T-cell lymphoblastic lymphoma (T-LBL). However, optimal conditioning regimen needs to be explored. In present study, 40 T-LBL undergoing allo-HSCT were retrospectively analyzed, including 23/40 (57.5%) total body irradiation (TBI)–based and 17/40 (42.5%) busulfan (BU)-based regimen. TBI–based significantly increased cumulative incidence (CI) grade II IV acute...

10.1177/09636897221108890 article EN cc-by-nc Cell Transplantation 2022-01-01

An all-optical full-adder is proposed based on cascaded second-order nonlinearities of sum-frequency generation and difference-frequency in quasi-phase-matched periodically poled lithium niobate (PPLN) waveguides. By utilizing the logic functions PPLN waveguides, a configuration waveguides designed to achieve full-adder. The waveforms, eye diagrams, extinction ratio, pulse width, peak power delay signals are calculated discussed numerically. results demonstrate that function can be achieved...

10.1109/jqe.2011.2161269 article EN IEEE Journal of Quantum Electronics 2011-07-07

After the epidemic in Wuhan City was brought under control 2020, local outbreaks of coronavirus disease 2019 (COVID-19) mainland China were mainly due to imported COVID-19 cases. The ongoing evolution severe acute respiratory syndrome 2 (SARS-CoV-2) has continued generate new variants. Some have been designated as variants concern (VOCs) by World Health Organization (WHO). To better assess role SARS-CoV-2 surveillance and prevalence VOCs 2021, genomic data from cases 2021 analyzed.The...

10.46234/ccdcw2022.144 article EN PubMed 2022-08-05

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant is the dominant circulating strain worldwide. To assess importation of SARS-CoV-2 variants in mainland China during epidemic, genomic surveillance data from imported disease 2019 (COVID-19) cases first half 2022 were analyzed.Sequences submitted January to July 2022, with a collection date before June 30, incorporated. proportions as well relationships between origin and destination each case analyzed.4,946...

10.46234/ccdcw2022.229 article EN China CDC Weekly 2022-01-01

Coronavirus disease 2019 (COVID-19) was designated a global pandemic by the World Health Organization (WHO) on March 11, 2020 (1).After great effort, COVID-19 has been well-controlled in China, but new challenges have emerged due to increasing numbers of imported cases from outside China.On May 8, Commission Jilin Province reported confirmed case 45-year-old laundry woman Shulan City northeast China.This suspected be associated with possible importation event.On 10, genome sequencing...

10.46234/ccdcw2020.115 article EN China CDC Weekly 2020-01-01

Before the coronavirus disease 2019 (COVID-19) outbreak on July 16, 2020, no new COVID-19 cases were reported in Urumqi City of Xinjiang for 150 consecutive days.During this outbreak, 826 confirmed have been Urumqi.The phylogenetic characteristics virus from clinical specimens initial 4 sequenced.The full-length genome sequencing was performed Illumina MiSeq platform, and sequences obtained outbreak.Compared with reference sequence EPI_ISL_402119 (1), which isolated Wuhan Hubei Province...

10.46234/ccdcw2020.206 article EN China CDC Weekly 2020-01-01

The increasing popularity of 6G communication within the Internet Vehicles (IoV) ecosystem is expected to induce a surge in both user numbers and data volumes. This expansion will cause substantial challenges ensuring network security privacy protection, as well addressing associated issue inadequate cloud computing resources. In this article, we propose Quantum Efficient Privacy Protection (QEPP) protocol that leverages reversible information hiding quantum point clouds. utilizes technology...

10.1109/tiv.2023.3304852 article EN IEEE Transactions on Intelligent Vehicles 2023-08-16

Abstract Silica carbon black (SiCB) was used as a natural carbon–silica dual‐phase filler (CSDPF) containing both biochar and silica, which obtained by pyrolysis of rice husks. The reinforcing performances SiCB were limited the large particle size poor surface activity. In this work, distribution particles modified ethanol‐assisted milling (S/E), increase in oxygen‐containing groups enhanced activity promoted grafting silane coupling agent (Si69). filler–rubber interfacial interactions when...

10.1002/pen.25850 article EN Polymer Engineering and Science 2021-11-16
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