Osman Zin Al-Abdin

ORCID: 0000-0001-5002-1334
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About
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Research Areas
  • Prostate Cancer Diagnosis and Treatment
  • AI in cancer detection
  • Antifungal resistance and susceptibility
  • Reproductive System and Pregnancy
  • Pain Mechanisms and Treatments
  • Pediatric Urology and Nephrology Studies
  • Image Retrieval and Classification Techniques
  • Ureteral procedures and complications
  • Pharmacological Effects of Natural Compounds
  • Apelin-related biomedical research
  • Prostate Cancer Treatment and Research
  • Radiomics and Machine Learning in Medical Imaging
  • Peptidase Inhibition and Analysis
  • Genital Health and Disease
  • Nigella sativa pharmacological applications
  • Helicobacter pylori-related gastroenterology studies
  • Hepatitis B Virus Studies
  • Biometric Identification and Security
  • Medical Imaging and Analysis
  • Urological Disorders and Treatments
  • Cancer survivorship and care
  • Organ Donation and Transplantation

King Saud University
2011-2018

McGill University Health Centre
2013

Institute for Research in Immunology and Cancer
2008

Université de Montréal
2008

ABSTRACT Upc2p, a transcription factor of the zinc cluster family, is an important regulator sterol biosynthesis and azole drug resistance in Candida albicans . To better understand Upc2p function C. , we used genomewide location profiling to identify transcriptional targets vivo. A triple hemagglutinin epitope, introduced at C terminus conferred gain-of-function effect on fusion protein. Location identified 202 bound promoters ( P < 0.05). Overrepresented functional groups genes whose...

10.1128/ec.00070-08 article EN Eukaryotic Cell 2008-04-05

Epidemiological studies have shown that the offspring of mothers who experience diabetes mellitus during pregnancy are seven times more likely to develop health complications than do not suffer from pregnancy. The present study was designed investigate whether supplementation streptozotocin (STZ)-induced diabetic pregnant mice with thymoquinone (TQ) and lactation improves risk developing acquired by their offspring. Three groups female were used: non-diabetic control dams (CD), (DD),...

10.1186/1476-511x-12-37 article EN cc-by Lipids in Health and Disease 2013-03-18

This review evaluated prostate cancer studies from around the world and investigated causes of differences among them. Prostate incidence mortality rates showed significant discrepancies between countries ethnicities. In North America as well in other western countries, most common was found to be cancer; however, it appears not prevalent men Middle East Africa. Statistics show that screening prostate-specific antigen levels should applied depending on ethnicity age. Other environmental...

10.15537/smj.2018.5.21986 article EN Saudi Medical Journal 2018-05-01

In this Paper, we introduce a new method for automatic recognition and classification of prostate cancer biopsy images based on Gleason grading system. The introduced algorithm combines features from wavelet transform fractal analysis domains. Biopsy are pre-processed prior to extraction using effective image processing algorithms analyze textural complexity in terms RGB color channels, edge segmentation information. Experimental results achieved an average accuracy 95 % set 45 with...

10.1109/icsmc.2011.6084080 article EN 2011-10-01

Pain is a common and dose-limiting side effect of many potentially curative cancer chemotherapeutic agents. This chemotherapy-induced pain (CIP) affects the quality life patients survivors hampers optimal clinical management chemotherapy in patients. The underlying mechanisms remain largely unknown, but changes levels cytokines/chemokines may contribute to pathophysiology CIP. retrospective study was aimed at examining whether plasma various cytokines change prostate after treatment such (if...

10.1093/pm/pnx145 article EN Pain Medicine 2017-05-16

Prostate cancer automatic grading has attracted a lot of attention during the last years [1]. Many research efforts have been fixated on development computerized recognition and classification systems to automatically grade Gleason patterns. Automatic methods can be classified into two basic classes: image textural-based class tissue structural-based (nuclear architecture, gland morphology) class. To best our knowledge, structural based three-class results including 3, 4 5 carcinoma were not...

10.1109/icsmc.2012.6378181 article EN 2022 IEEE International Conference on Systems, Man, and Cybernetics (SMC) 2012-10-01

Few studies have addressed racial differences in prostate cancer (PCa) detection between Western and Arabian countries, although PCa has a significantly lower prevalence Arabic populations compared to populations. Therefore, an explanation of this difference is lacking. Serum prostate-specific antigen (PSA) valuable marker used select patients who should undergo biopsies, the manner which it may require adjustments based on ethnic population question. We investigated rate Canadian Saudi A...

10.1590/1414-431x20132757 article EN cc-by Brazilian Journal of Medical and Biological Research 2013-06-01
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