- COVID-19 Clinical Research Studies
- Microfluidic and Capillary Electrophoresis Applications
- Biomarkers in Disease Mechanisms
- Allergic Rhinitis and Sensitization
- Neutropenia and Cancer Infections
- Biosensors and Analytical Detection
- Inflammasome and immune disorders
- Vitamin D Research Studies
- Cholinesterase and Neurodegenerative Diseases
- Bioactive Compounds in Plants
- Plant Pathogens and Fungal Diseases
- Plant and animal studies
- Pomegranate: compositions and health benefits
- COVID-19 and healthcare impacts
- Botany and Geology in Latin America and Caribbean
- Shoulder and Clavicle Injuries
- Contact Dermatitis and Allergies
- Circular RNAs in diseases
- Occupational and environmental lung diseases
- Receptor Mechanisms and Signaling
- Food Allergy and Anaphylaxis Research
- Eicosanoids and Hypertension Pharmacology
- Electrochemical Analysis and Applications
- Public Health in Brazil
- Cardiac electrophysiology and arrhythmias
Hospital Universitario Virgen de las Nieves
2018-2022
Universitat de Miguel Hernández d'Elx
2014
Universidad de Murcia
2008
Zamorano Pan-American Agricultural School
1995
IL-6 is one of the major mediators hyper-inflammatory responses with complex biological functions as it can signal via different modes action. by classical signalling has anti-inflammatory and antibacterial activities, while trans-signalling mediates pro-inflammatory effects. The net effect established multiple factors beyond its absolute concentration. Here, we assess relationship between variables [IL-6, soluble IL-6R (sIL-6R) gp130 (sgp130)] outcomes in a cohort 366 COVID-19 patients....
Background A rare and benign cause of isolated aspartate aminotransferase (AST) increase is due to the presence macro (macro‐AST). Macro‐AST not usually considered by clinicians, leading a large number unnecessary even invasive tests before diagnosed. Most commonly used laboratory methods for detection macro‐enzymes are precipitation with polyethylene glycol (PEG), ultracentrifugation gel filtration chromatography (GFC). Methods We report case an asymptomatic patient persistent AST...
Background and aims: Vitamin D inadequacy may be involved in the mechanisms of SARS-CoV-2 infection potential risk factors for disease propagation or control coronavirus 2019 (COVID-19). This study assessed a short-term evolution vitamin status its influence upon different clinical parameters critically ill patients with COVID-19. Methods: A prospective analytical which 37 volunteers between 41 71 years age COVID-19 were evaluated at baseline three days intensive care unit (ICU) stay....
Dimethyl-celecoxib is a celecoxib analog that lacks the capacity as cyclo-oxygenase-2 inhibitor and therefore life-threatening effects but retains antineoplastic properties. The action mechanism at molecular level unclear. Our in vitro assays using sarcoplasmic reticulum preparation from rabbit skeletal muscle demonstrate dimethyl-celecoxib inhibits Ca2+-ATPase activity ATP-dependent Ca2+ transport concentration-dependent manner. Celecoxib was more potent of than dimethyl-celecoxib, deduced...