- Migration and Labor Dynamics
- Migration, Ethnicity, and Economy
- CRISPR and Genetic Engineering
- Insect symbiosis and bacterial influences
- Evolution and Genetic Dynamics
- Socioeconomic Development in Asia
- Malaria Research and Control
- International Development and Aid
- Gender, Labor, and Family Dynamics
- Diaspora, migration, transnational identity
- Income, Poverty, and Inequality
- Gender Politics and Representation
- European Criminal Justice and Data Protection
- Poverty, Education, and Child Welfare
- Migration, Health and Trauma
- Mosquito-borne diseases and control
- Urban and Rural Development Challenges
- Insect Resistance and Genetics
- Migration, Refugees, and Integration
- Political Economy and Marxism
- Insect behavior and control techniques
- Land Rights and Reforms
- Advanced biosensing and bioanalysis techniques
- Housing, Finance, and Neoliberalism
- Monoclonal and Polyclonal Antibodies Research
Imperial College London
2021-2025
Royal Holloway University of London
2008-2021
University of Birmingham
2019-2020
ETH Zurich
2020
University of Sheffield
2009-2014
Universidad de Londres
2005
University of Liverpool
1995-2003
McMaster University
1982
St. Joseph Hospital
1982
Abstract Genetic control – the deliberate introduction of genetic traits to a pest or vector population offers powerful tool augment conventional mosquito tools that have been successful in reducing malaria burden but are compromised by range operational challenges. Self-sustaining strategies shown great potential laboratory settings, hesitancy due their invasive and persistent nature may delay implementation. Here, instead, we describe self-limiting strategy, designed geographically...
The international migration of professional workers has increased in scope over the past 20 years as skilled are needed when companies’ activities cross national borders. While this trend been recognised from an economic perspective, much less researched a social and cultural angle. Using case studies British Singaporean to China, paper employs comparative frame examine effect differences—both terms business culture well norms regarding ethnicity gender—on dynamics ‘contact zones’ emerging...
This paper challenges the systematic, though often unacknowledged, gendered nature of much current globalisation discourse and argues for need to give attention dimensions transnational flows people into global cities and, relatedly, gendering metropolitan space in process. The focuses on Singapore, an aspiring city, investigate how city spaces are transgressed by migrants who may challenge, inflect or reaffirm spatial boundaries with which is scripted. In particular, it three groups women –...
Abstract Work on transnationalism potentially reshapes the way we think of key concepts which serve to 'ground' contemporary social life in specific localities as well those 'transgress' or 'destabilize' these groundings. Focusing 'edges' sites analysis allows us consider local identifications and transgressive unmoorings within same frame. We discuss two main themes have emerged literature: 'transnational morphologies', terms shape, contours structure transnationality processes agencies...
WILLIS K. D. and YEOH B. S. A. (2000) Gender transnational household strategies: Singaporean migration to China, Reg. Studies 34 , 253‐264. Increases in international flows of highly-skilled migrants have been characteristic the economic globalization process. Professional managerial employees are increasing demand as companies expand their locations operation. However, research on these skilled migrants' movements has predominantly linked firm itself, focusing productive sphere alone. This...
CRISPR-based homing gene drives can be designed to disrupt essential genes whilst biasing their own inheritance, leading suppression of mosquito populations in the laboratory. This class relies on CRISPR-Cas9 cleavage a target sequence and copying ('homing') therein drive element from homologous chromosome. However, site mutations that are resistant yet maintain function expected strongly selected for. Targeting functionally constrained regions where not easily tolerated should lower...
While the release of sterile males has been highly successful in suppressing some pest populations, it is impractical for many species due to disappearing after a single generation, necessitating large, repeated releases maintain sufficient impact. Synthetic gene drives promise more efficient approaches since they can increase frequency from rare, yet this also allows them spread across landscape, which may not always be desired. Between these two extremes are selectively neutral genetic...
In this article the authors offer an analysis of Singapore's state-vaunted 'go-regional' policy as a case study to illustrate argument that not only are 'nation-state' and 'diaspora' structurally interdependent embedded in discursive frame each other, but also way they interlock is shaped by particular gender ideologies relations. same state articulates nationalism appealing men women gendered subjects, appropriation transnational space part regionalisation drive serves extend elaborate...
A disintegrin and metalloprotease 10 (ADAM10) is a transmembrane protein essential for embryonic development, its dysregulation underlies disorders such as cancer, Alzheimer's disease, inflammation. ADAM10 "molecular scissor" that proteolytically cleaves the extracellular region from >100 substrates, including Notch, amyloid precursor protein, cadherins, growth factors, chemokines. has been recently proposed to function six distinct scissors with different depending on association one of...
Synthetic gene drive constructs could, in principle, provide the basis for highly efficient interventions to control disease vectors and other pest species. This efficiency derives part from leveraging natural processes of dispersal flow spread construct its impacts one population another. However, sometimes (for example, with invasive species) only specific populations are need control, on non-target would be undesirable. Many designs use nucleases that recognise cleave genomic sequences,...
The Sustainable Development Goals (SDGs) represent a continuation of the global agreement on development targets achieved through previous Millennium (MDGs). However, there are significant changes, most notably in range goals and inclusion Global North, as well South countries. This Viewpoint outlines some shifts examines their implications for international planning.
ABSTRACT Genetic control – the deliberate introduction of genetic traits to a pest or vector population offers powerful tool augment conventional mosquito tools that have been successful in reducing malaria burden but are compromised by range operational challenges. Self-sustaining strategies shown great potential laboratory settings hesitancy due their invasive and persistent nature may delay implementation. Here instead we describe self-limiting strategy, designed geographically and/or...
Abstract Whilst the release of sterile males has been highly successful in suppressing some pest populations, it is impractical for other species due to disappearing after a single generation, necessitating large, repeated releases maintain sufficient impact. Synthetic gene drives promise more efficient approaches since they can increase frequency from rare, yet this also allows them spread across landscape, which may not always be desired. Between these two extremes are selectively neutral...
There have been few analyses of heterosexuality in the context migration, particularly within Asia. As a corrective, this themed issue we bring together four articles to contribute debates on fluidity and how performance has particular spatialities East South-East Each article uses ethnographic methods produce nuanced specific spatially contingent performances heterosexuality. A migration focus illuminates spatial dislocation provides opportunities for both men women play out different...
The sterile insect technique (SIT) has been successful in controlling some pest species but is not practicable for many others due to the large number of individuals that need be reared and released. Previous computer modelling demonstrated release males carrying a Y-linked editor kills or sterilises female descendants could orders magnitude more efficient than SIT while still remaining spatially restricted, particularly if combined with an autosomal sex distorter. In principle, further...
Walt Whitman Rostow's stages of economic growth theory continues to appear in curricula and textbooks on development geography despite being originally published 1960 criticised for its Eurocentrism. This 'Spotlight On … ' article provides an overview ideas, their influence why modernisation ideas are still relevant understanding how is defined implemented.