Lowilius Wiyono

ORCID: 0000-0001-5018-7676
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Research Areas
  • Computational Drug Discovery Methods
  • Diabetes Management and Research
  • Medicinal Plant Research
  • Diabetes Treatment and Management
  • Advanced biosensing and bioanalysis techniques
  • Biosensors and Analytical Detection
  • SARS-CoV-2 detection and testing
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Pancreatic function and diabetes
  • Nanoparticle-Based Drug Delivery
  • COVID-19 Clinical Research Studies
  • COVID-19 and healthcare impacts
  • SARS-CoV-2 and COVID-19 Research
  • Hemophilia Treatment and Research
  • Cancer Research and Treatment
  • Chemotherapy-induced cardiotoxicity and mitigation
  • Ginger and Zingiberaceae research
  • Viral Infections and Outbreaks Research
  • PARP inhibition in cancer therapy
  • Olfactory and Sensory Function Studies
  • Multiple Myeloma Research and Treatments
  • Animal Virus Infections Studies
  • CRISPR and Genetic Engineering
  • Metabolomics and Mass Spectrometry Studies
  • Vaccine Coverage and Hesitancy

University of Indonesia
2018-2025

Rumah Sakit Umum Pusat Nasional Dr. Cipto Mangunkusumo
2021-2024

University of Brawijaya
2021

National Brain Centre
2021

Member countries of the Association Southeast Asian Nations (ASEAN) have faced dengue outbreaks for decades, and region has one highest rates globally. Outbreaks continue to occur concurrently with coronavirus disease 2019 (COVID-19) pandemic in 10 ASEAN countries. Both infectious diseases pose a tremendous burden these related both infection control economy. Increases number cases occurred part due disruptions pathogen-host-vector relationship caused by changes human behaviour response...

10.4178/epih.e2021070 article EN cc-by Epidemiology and Health 2021-09-16

The Association of Southeast Asian Nations (ASEAN) region is known to be a global hotspot viral outbreaks because many factors. To limit the impact future outbreaks, it crucial for ASEAN governments strengthen regional virology research capacity. have collaborated in several initiatives, with most recent being establishment Regional Center Public Health Emergencies and Emerging Diseases. However, challenges, including technology disparities, nationalistic tendencies, lack public acceptance...

10.4269/ajtmh.21-0589 article EN cc-by American Journal of Tropical Medicine and Hygiene 2021-09-10

Breast cancer is the 3rd most common in world and one women. An alternative pharmacological treatment for breast needed. Kaempferia pandurata an endemic plant Asia which known its biological activity, of anticancer activity with abundant bioactive compound, pinostrobin. The rhizome dried extracted using maseration n-Hexane solvent. extract then isolated recrystallization method methanol solvent to produce pinostrobin crystal. Pinostrobin manufactured into nanoparticle chitosan sodium...

10.5958/0974-360x.2020.00497.7 article EN Research Journal of Pharmacy and Technology 2020-01-01

Introduction: Indonesia, as a developing country, has limited data on the factors associated with 30-day mortality in COVID-19 patients Indonesia. As matter of fact, study analyzing infection Indonesia never been conducted. This aims to fill this gap literature by conducting large-scale analysis Method: employed single-center retrospective cohort observational design, and was conducted at Cipto Mangunkusumo National General Hospital between years 2022 2023. Sampling using consecutive...

10.3390/jcm13102998 article EN Journal of Clinical Medicine 2024-05-20

Coronavirus disease 2019 (COVID-19) has been extensively researched, particularly with regard to COVID-19 vaccines. However, issues logistics and availability might cause delays in vaccination programs. Thus, the efficacy safety of half-dose heterologous mRNA should be explored. This was an open-label observational study evaluate immunogenicity mRNA-1273 as a booster vaccine among adults aged >18 years who underwent complete primary SARS-CoV-2 (severe acute respiratory syndrome...

10.3390/vaccines12040344 article EN cc-by Vaccines 2024-03-22

Background: Biliary atresia (BA) is a neonatal condition characterized by the obstruction of extrahepatic bile ducts. Case: A 2-year-old female with BA underwent Kasai procedure at 3 months age. Despite surgery, she developed persistent jaundice and abdominal enlargement. Preoperative laboratory findings revealed elevated liver enzymes, GGT, bilirubin levels. This case raises clinical question whether preoperative GGT levels can predict JC after procedure, in addition to its role diagnosis....

10.58427/apghn.3.3.2024.20-31 article EN cc-by-nc Deleted Journal 2024-08-31

Type 1 diabetes mellitus, which is the most common type of among children, not curable but can be managed well without a negative effect on quality life. One treatments mellitus carbohydrate counting. This systematic review and meta-analysis sought to evaluate efficacy counting with regard hemoglobin A1c (HbA1c) reduction in children mellitus.Nine studies were assessed, primary outcome being glycemic control (HbA1c changes). We searched following electronic databases: ProQuest, PubMed,...

10.6065/apem.2244242.121 article EN cc-by-nc Annals of Pediatric Endocrinology & Metabolism 2023-09-25

Abstract Human‐induced climate change poses a pervasive threat to the world. Human activities, such as deforestation, farming livestock, and burning fossil fuels, are key drivers of change. Like other regions, Southeast Asian region is greatly impacted by The article focuses on examining current landscape adaptation health preparedness among indigenous populations in Asia (SEA). Climate will affect disproportionately. Over years, people living SEA have faced increasing challenges. For...

10.1002/puh2.129 article EN cc-by Public Health Challenges 2023-10-12

Abstract The Kanjuruhan tragedy has caused tremendous sorrow for Indonesia and its football history. incident happened during the match between Arema Persebaya teams that was followed by a chaotic stampede due to supporters’ anarchy. 135 deaths in stadium. However, it also brought into limelight several violations depravity of safety measures have been neglected Indonesian officials association. Despite being banned FIFA's Safety Security Regulations, use crowd‐control gas is hypothesized as...

10.1002/puh2.139 article EN cc-by Public Health Challenges 2023-11-15

Breast cancer most commonly occurs in women worldwide, 2012 there were 1.670.000 cases with the second prevalence world (25% of total incidence cancer). Drugs used so far have not been effective and many resistance occurs, it is necessary to a discovery herbs that contain polyphenols as anticancer. Kaempferia pandurata Roxb plant has identified various essential oils several flavonoid compounds demonstrated biological activities. This research was done by simulation study molecular docking...

10.5958/0974-360x.2019.00400.1 article EN Research Journal of Pharmacy and Technology 2019-01-01

Breast cancer is the most common worldwide and in Indonesia. Kaempferia pandurata Roxb. a herbal plant from South-East Asia which known for its ability to inhibit growth of Estrogen Receptor (ER) + breast cell line former study. However, effect on ER- lines had not been studied. Therefore, we want examine cytotoxicity K. (MDA-MB-231). Nanoparticle form preparation that optimizes activity any compound targeted cell. it expected can increase effectivity anticancer In this study, rhizome...

10.5530/pj.2020.12.17 article EN Pharmacognosy Journal 2020-02-10

Hemiarthroplasty becomes the procedure of choice for hip fracture in elderly population with blood loss as its complication. Tranexamic acid (TXA) has been used no systematic review conducted to evaluate efficacy and safety. The PRISMA guidelines were followed conduct literature screening selection. Main outcomes extracted qualitative analysis quantitative analysis. Blood level haemoglobin drop was significantly reduced TXA group compared control group. is also deemed protective factor...

10.37515/ortho.8231.6202 article EN Hong Kong Journal of Orthopaedic Research 2023-08-30
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