A5059363432- Fungal Infections and Studies
- Corneal Surgery and Treatments
- Antifungal resistance and susceptibility
- RNA and protein synthesis mechanisms
- 3D Printing in Biomedical Research
- Antimicrobial Peptides and Activities
- Toxoplasma gondii Research Studies
- Immune Response and Inflammation
- Electrospun Nanofibers in Biomedical Applications
- RNA Interference and Gene Delivery
- Nanoparticle-Based Drug Delivery
- Advanced biosensing and bioanalysis techniques
- Iron oxide chemistry and applications
- Tissue Engineering and Regenerative Medicine
- Inhalation and Respiratory Drug Delivery
Universidade Federal de Minas Gerais
2015-2024
A novel, fast, low-cost and scalable methodology to prepare stable magnetoliposomes (MGLs), without the use of organic solvents, is described.The concept work based on dual soy lecithin associated a new liposome preparation methodology.Soy was used coat nanoparticles magnetite (Fe 3 O 4 @lecithin) for encapsulation Fe @lecithin (Lip-Fe @lecithin).Liposomes with size less than 160 nm, polydispersity index 0.25 zeta potential -41 mV, were prepared autoclave sonication.The liposomal...
Paracoccidioidomycosis is caused by fungi of the Paracoccidioides genus and constitutes most prevalent deep mycosis in Latin America. Toll-like receptors promote immune response against infectious agents. Recently, it was reported that TLR9 crucial for mice survival during first 48 h P. brasiliensis infection. In this study, we used CPG oligodeoxynucleotide motif as an adjuvant with without rPb27 to immunize Paracoccidioidomycosis. induced differential recruitment lymphocytes inflammatory...
Cancer is one of the deadliest diseases worldwide and has been responsible for millions deaths. However, developing a satisfactory smart multifunctional material combining different strategies to kill cancer cells poses challenge. This work aims at filling this gap by composite treatment through hyperthermia drug release. With purpose, magnetic nanoparticles were coated with polymer matrix consisting poly (L-co-D,L lactic acid-co-trimethylene carbonate) poly(ethylene oxide)–poly(propylene...
Abstract Breast cancer is the most common in women. Although chemotherapy still broadly used its treatment, adverse effects remain a challenge. In this scenario, aptamers emerge as promising alternative for theranostic applications. Studies using breast cell lines provide useful information laboratory and preclinical investigations, of which use established from metastatic sites. However, these correspond to populations late stage tumor progression. On other hand, studies cells primary sites...