A5055185113- Drug Solubulity and Delivery Systems
- Advanced Drug Delivery Systems
- Synthesis and biological activity
- Medicinal Plants and Neuroprotection
- Computational Drug Discovery Methods
- Natural Antidiabetic Agents Studies
- Pancreatic function and diabetes
- Pharmacological Effects of Natural Compounds
- Phytochemicals and Antioxidant Activities
- Advancements in Transdermal Drug Delivery
- Neurological Disorders and Treatments
- Click Chemistry and Applications
- Pain Mechanisms and Treatments
- Metabolism, Diabetes, and Cancer
- Skin Protection and Aging
- Pharmaceutical studies and practices
- Cancer-related molecular mechanisms research
- Pulmonary Hypertension Research and Treatments
- Curcumin's Biomedical Applications
- Epigenetics and DNA Methylation
- Pharmacology and Obesity Treatment
- Drug-Induced Hepatotoxicity and Protection
- Circular RNAs in diseases
- Nerve injury and regeneration
- Medicinal Plants and Bioactive Compounds
Al Ain University
2020-2024
Uttarakhand Technical University
2013
Qassim University
2011
Nanosuspension has emerged as an effective, lucrative, and unequalled approach for efficiently elevating the dissolution bioavailability of aqueous soluble drugs. Diverse challenges persist within this domain, demanding further comprehensive investigation exploration. This study aims to design, develop, optimise formulation process variables, characterise stabilised dissolvable nanosuspension using chlorthalidone a BCS class- IV drug. Nanosuspensions drug were prepared combination topdown...
Chlorthalidone nanocrystals were developed via lyophilization with the aid of cryoprotectants. To produce stable and free-flowing chlorthalidone nanocrystals, various cryoprotectants including trehalose, mannitol, sucrose, polyethylene glycol (PEG), glycerol, glucose considered, their impact on viability characteristics investigated. This was accomplished by characterizing considering different parameters such as particle size, polydispersity index (PDI), surface charge, properties,...
Cancer is a leading cause of death worldwide. Using network pharmacology and molecular docking techniques, this study aims to investigate the mechanism novel indole-quinoline derivative (SM7) in cancer by predicting chain hallmarks that can be targeted subsequently inhibited treat with improved therapeutic effect. Out total 25005 number targets, 93 targets SM7 were identified overlapped. David KEGG analysis retrieved 15 signaling pathways. Molecular primary ie. STAT3, BCL2, ALB, MMP9 through...
Diabetes retinopathy (DR) is the leading cause of blindness and considered as most ordinary microvascular complication diabetes mellitus (DM). The current available therapies can only be effective in progressive stages DR there are various clinical studies which depicts inconclusive outcomes these after assessing long-term efficacy safety such treatments. Moreover, an indispensable need a more reliable well potent treatment efficacious for management DR. possible at early with polyphenols...
Abstract: The term “neurodegenerative disorders” refers to a group of illnesses in which deterioration nerve structure and function is prominent feature. Cognitive capacities such as memory decision-making deteriorate result neuronal damage. primary difficulty that remains safeguarding neurons since they do not proliferate or regenerate spontaneously are therefore substituted by the body after have been damaged. Millions individuals throughout world suffer from neurodegenerative diseases....
Abstract: Background: In a research facility, 7-azaindole derivatives were designed and synthesized, each substance was examined for its capacity to inhibit cancer growth. the present study, synthesized analogues docked with PARP enzyme find suitable site inhibition. Materials Methods: 1H nuclear magnetic resonance, 13C NMR, mass spectrometry used characterize all of 7-azindole. On MCF-7 cell line breast cancer, their anticancer activity assessed. The proteins PARP-1 inhibitors against using...