A5042441301- Catalytic C–H Functionalization Methods
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Sulfur-Based Synthesis Techniques
- Catalytic Cross-Coupling Reactions
- Fluorine in Organic Chemistry
- Synthesis and Catalytic Reactions
- Asymmetric Hydrogenation and Catalysis
- Nitrogen and Sulfur Effects on Brassica
- Chemical Synthesis and Reactions
- Innovative Microfluidic and Catalytic Techniques Innovation
- Metal-Organic Frameworks: Synthesis and Applications
- Asymmetric Synthesis and Catalysis
- Chemical Synthesis and Analysis
- Potato Plant Research
- Gold and Silver Nanoparticles Synthesis and Applications
- Radical Photochemical Reactions
- Soybean genetics and cultivation
- Nanocluster Synthesis and Applications
Sichuan University
2019-2024
State Key Laboratory of Biotherapy
2019-2024
Qingdao University of Science and Technology
2023-2024
Northwest A&F University
2024
Weifang University of Science and Technology
2022
Jining Medical University
2021
State Key Laboratory of Crystal Materials
2019
Shandong University
2019
A commercially available and versatile dehydrative amidation catalyst, featuring a thianthrene boron acid structure, has been developed. The catalyst shows high catalytic activity to both aliphatic less reactive aromatic carboxylic substrates, including several bioactive or clinical molecules with group.
A unique triple core–shell Ag<sub>84</sub> nanocluster displaying isomerism, which is controlled by different carboxylic acids and a one-way transformation (<bold>SD/Ag84a</bold> <bold>SD/Ag84b</bold>).
A nickel-catalyzed cross-electrophile coupling reaction between (hetero)aryl bromides and 2,2-difluorovinyl tosylate is presented. This protocol provides facile incorporation of the gem-difluorovinyl moiety in organic molecules. The method features mild conditions, good functional group tolerance, excellent yields. Furthermore, mechanistic experiments DFT studies indicate a Ni(0)/Ni(II) catalytic cycle, thus differing from currently accepted cycle for C(sp2)–C(sp2) reactions.
Abstract A novel catalytic system for radical cross‐coupling reactions based on copper and chiral Pyridyl‐bis(imidazole) (PyBim) ligands is described. It overcomes the challenges of chemoselectivity enantioselectivity, achieving a highly enantioselective vicinal sulfonyl‐esterification reaction alkenes involving sulfur dioxide. This strategy involves use earth‐abundant metal catalyst, mild conditions, broad range substrates (84 examples), high yields (up to 97% yield), exceptional control...
A 1,3-sulfonyl migration of difluorovinyl sulfonates initiated by a catalytic amount silver fluoride is presented. α,α-Difluoro-β-ketosulfones were successfully prepared in excellent yields. This method features high chemoselectivity, good functional group tolerance, atom economy, and mild, environmentally benign reaction conditions. Furthermore, mechanistic experiments indicate that this proceeds an intermolecular pathway the corresponding sulfinates are possible intermediates.
The catalytic conversion of sulfonates, a versatile class pharmaceutical intermediates, is usually based on C-O bond cleavage. In this paper, however, we discover rare transformation sulfonates via S-O cleavage catalyzed by transition metal, through which alkyl could undergo an intramolecular desulfitative coupling to form aryl ethers in the presence nickel catalyst. Meanwhile, perform similarly give diaryl palladium complex. This tolerate wide range functionalities. Controlled experiments...
A dual nickel-/palladium-catalyzed gem -difluorovinylation of alkynyl bromoarenes is presented. This method proceeds smoothly to afford various dihydrobenzofuran compounds containing gem-difluorovinyl fragments with excellent stereoselectivities.
A nickel-catalyzed intramolecular C-N coupling reaction via SO2 extrusion is presented. The use of a catalytic amount BPh3 allows the transformation to take place under much milder conditions (60 °C) than previously reported reactions by CO or CO2 (160-180 °C). In addition, this method displays good functional group tolerance and versatility, as it can be applied synthesis dialkyl aryl amines, alkyl diaryl triaryl amines. robustness desulfitative demonstrated three high-yielding gram-scale reactions.
Summary Hydrogen sulfide (H 2 S) is an endogenous gaseous signaling molecule, which has been shown to play important role in plant growth and development by coupling with various phytohormones. However, the relationship between H S cytokinin (CTK) mechanisms CTK affect root remain poorly understood. Endogenous was analyzed UHPLC‐ESI‐MS/MS. Persulfidation of oxidase/dehydrogenases (CKXs) mass spectrometry (MS). ckx2/CKX2 wild‐type (WT) , OE CKX2 Cys(C)62alanine(A) transgenic lines were...
Herein, we report a convenient solvent-controlled regioselective esterification to access two types of carboxylate esters without any additive or non-green activation strategy. In this transformation, 2-methyleneaziridines served as an ester reagent, providing alternative electrophilic carbon centers. Notably, protocol is suitable for some structure-complicated clinical molecules with carboxylic acid group, presenting remarkable application potential.
We have developed a regioselective C–N cross-coupling of 1,2,4-thiadiazoles with sulfonyl azides through iridium catalysis in water.