A5028896050- Advanced Neuroimaging Techniques and Applications
- Functional Brain Connectivity Studies
- Advanced MRI Techniques and Applications
- Cancer, Stress, Anesthesia, and Immune Response
- Anesthesia and Pain Management
- Botulinum Toxin and Related Neurological Disorders
- Spinal Hematomas and Complications
- Birth, Development, and Health
- Treatment of Major Depression
- Musculoskeletal pain and rehabilitation
- Spinal Dysraphism and Malformations
- Tryptophan and brain disorders
- Neuropeptides and Animal Physiology
- Spine and Intervertebral Disc Pathology
- Neuroscience and Neuropharmacology Research
- Neurogenesis and neuroplasticity mechanisms
- Pain Management and Placebo Effect
- Electrolyte and hormonal disorders
- Surgical Simulation and Training
- Nausea and vomiting management
- Cerebrospinal fluid and hydrocephalus
- Pain Mechanisms and Treatments
- Neurotransmitter Receptor Influence on Behavior
- Metabolomics and Mass Spectrometry Studies
- Pharmacological Effects and Toxicity Studies
University College Dublin
2015-2024
Royal College of Surgeons in Ireland
2021-2024
St. Vincent's University Hospital
2018-2024
Trinity College
2021
Trinity College Dublin
2021
Mater Misericordiae University Hospital
2015-2018
University Hospital Limerick
2018
Haliç University
2018
Jahrom University of Medical Sciences
2018
Alborz University of Medical Sciences
2018
Pre-eclampsia is a multisystem disorder with incidence rates ranging from 2% to 5%. Hyponatraemia rare complication of pre-eclampsia. A 41-year-old, para 0+1 in vitro fertilisation monochorionic diamniotic triplet pregnancy woman presented at 25 weeks dyspnoea and general malaise. Her antenatal course was complicated by the diagnosis intrauterine growth restriction one 27 gestation. At 27+3 gestation, she diagnosed as having Subsequent biochemical analysis demonstrated hyponatraemia serum...
Introduction Chronic pain is defined as lasting longer than 3 months. This often causes persistent emotional distress and functional disability that refractory to conventional treatments. Emerging evidence suggests oral Ketamine therapy may have a specific role in managing treatment-resistant chronic pain. study aimed assess the effectiveness of ketamine within tertiary management clinic. Methods was clinic-based retrospective descriptive 79 patients with broad range diagnoses treated over...
The Stria Medullaris Thalami is a discrete white matter tract that directly connects frontolimbic areas to the habenula, allowing forebrain influence midbrain monoaminergic output. Habenular dysfunction has been shown in various neuropsychiatric conditions. However, there exists paucity of research into habenula's principal afferent tract, stria medullaris. Diffusion-weighted tractography may provide insights properties medullaris vivo, opening up investigation this conditions monoamine...
Magnetic resonance spectroscopy (MRS) is a non-invasive analytical technique that investigates the presence and concentrations of brain metabolites. In context major depressive disorder (MDD), MRS has revealed regional biochemical changes in GABA, glutamate, choline across different compartments. Technical methodological advances data acquisition, particular proton-based 1H-MRS, have resulted significant increase incidence reports utilizing for psychiatric research diagnosis. The most recent...
Emerging evidence suggests that methadone has a specific role in the management of treatment resistant cancer-related pain. Objectives To investigate utilisation pattern, safety and efficacy prescribed as an analgesic for complex pain acute hospital inpatient setting. Methods A retrospective longitudinal observational study patients between April 2020 July 2021 was performed. Changes coprescribed baseline opioid, use breakthrough opioid analgesic, patient rated scores adverse side effects...
Reclining on the lyra of fornix, dorsal hippocampal commissure (DHC) facilitates communication between left and right hippocampi. Despite being a key commissural fiber bundle hippocampus, DHC remains relatively underexplored in humans. Using high-resolution T1 T2 magnetic resonance imaging conjunction with High Angular Resolution Diffusion Imaging Constrained Spherical Deconvolution tractography, we investigated if there are differences sample 54 healthy controls 38 patients diagnosed Major...
This study aims to assess the cervical spine positioning of consultant and trainee hand surgeons during standardised surgeries, focusing on prevalence sustained end-range postures, particularly flexion.
<title>Abstract</title> Background - The amygdala is involved memory and emotion processing communicates with the rest of brain through three efferent tracts: stria terminalis (ST), ventral amygdalofugal pathway (VAP), anterior commissure (AC). This first study to isolate all major amygdalar output pathways using novel diffusion tractography protocols exploration diffusion, age, sex characteristics each tract. Methods − 64 healthy individuals aged 15–64 underwent high-resolution T1, T2, MR...
This case presents a 35-year-old male with spinal predominant neurofibromatosis-1 who developed an incomplete cord injury (C3 Asia C) which did not improve despite urgent decompressive surgery for multiple cervical neurofibromas. report outlines novel indication intrathecal baclofen. The patient suffered from lower limb weakness severe spasticity and required assistance of at least two all activities. aim rehabilitation was to overall tone while focusing on independence, mobility quality...
A 31-year-old male patient with chronic constipation of unknown aetiology presented emergently worsening nausea, vomiting and abdominal distension one week duration. On examination, his abdomen was distended minimal tenderness. plain film the demonstrated severe faecal loading. The haemodynamically unstable on admission appeared sick. An urgent CT pelvis conducted showing extensive rectal dilatation associated proximal colonic stercoral perforation. proceeded straight to theatre for...
Abstract Although intrathecal pumps may lead to spinal symptoms that are likely related the pump itself, case presented herein underscores importance of casting a broad differential diagnosis at time initial presentation.
Background: Postoperative pain is a major problem with high prevalence up to 95% in developing countries.It may increase postsurgical complications which can delay discharge and costs.Objective: To determine the prevalence, acceptance, physical limitation predictors for postoperative electively operated patients at Kilimanjaro Christian Medical Center (KCMC) Tanzania.Materials methods: An observational study was carried out KCMC from December 2016 April 2017.All above 18 years, admitted...
A patient presented with cauda equina syndrome signs on a background of intrathecal pump implantation for chronic pain. Initial investigations were consistent granuloma, common complication pumps. CSF cytometery revealed lymphocytosis. This represented 2 months later neck secondary to B-cell-lymphoma.