Emily R. Siniscalco

ORCID: 0000-0001-5065-1854
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About
Contact & Profiles
Research Areas
  • Immune Cell Function and Interaction
  • Immunotherapy and Immune Responses
  • Food Allergy and Anaphylaxis Research
  • T-cell and B-cell Immunology
  • IL-33, ST2, and ILC Pathways
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Asthma and respiratory diseases
  • Nicotinic Acetylcholine Receptors Study
  • RNA Interference and Gene Delivery
  • Genetics, Bioinformatics, and Biomedical Research
  • Diabetes and associated disorders
  • Vagus Nerve Stimulation Research
  • Galectins and Cancer Biology
  • Escherichia coli research studies
  • Immunodeficiency and Autoimmune Disorders
  • Reproductive System and Pregnancy
  • Biomedical and Engineering Education
  • Transgenic Plants and Applications
  • Complement system in diseases
  • CRISPR and Genetic Engineering

Northwestern University
2022-2024

Yale University
2021-2024

Ithaca College
2018

Abstract DOCK8 deficient patients have elevated food specific IgE and severe allergy. In Dock8-/- mice, we showed that T cell intrinsic restrains the development of IL-13 expressing follicular helper (Tfh13) cells drive anaphylactic production. Oral exposure to results in tolerance, yet loss (T-Dock8-/-) is sufficient Tfh13 differentiation peanut IgE. How prevents unknown. human cells, promotes STAT3 phosphorylation, an inhibitor GATA3. We show mouse activity STAT3-/- differentiate into...

10.4049/jimmunol.212.supp.0620.4120 article EN The Journal of Immunology 2024-05-01

As undergraduates, science students receive the educational foundation required for their future STEM careers. They build knowledge base of basic concepts, as well learn hands-on skills that will help them in fields [1,2]. Often, this education is transmitted through lectures and teaching labs, where play a passive role. However, undergraduate research experiences can serve more enriching alternative to such methods by combining biological concepts with laboratory context novel scientific...

10.33805/2638-7735.110 article EN Biochemistry and Modern Applications 2018-08-23

Complement signaling on B cells affects germinal center dynamics.

10.1126/sciimmunol.abk1556 article EN Science Immunology 2021-07-02
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