A5080304284- Multiple Sclerosis Research Studies
- Cerebral Palsy and Movement Disorders
- Myasthenia Gravis and Thymoma
- Balance, Gait, and Falls Prevention
- Vestibular and auditory disorders
- Parkinson's Disease and Spinal Disorders
- Autoimmune and Inflammatory Disorders Research
- Musculoskeletal pain and rehabilitation
- Family and Disability Support Research
- Mycobacterium research and diagnosis
- Resilience and Mental Health
- Fungal Infections and Studies
- Diabetic Foot Ulcer Assessment and Management
- HIV Research and Treatment
- Foot and Ankle Surgery
- Medical and Biological Sciences
- Parkinson's Disease Mechanisms and Treatments
- Effects of Vibration on Health
- Yersinia bacterium, plague, ectoparasites research
- Interprofessional Education and Collaboration
- Bacillus and Francisella bacterial research
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Materials Engineering and Processing
- Neurological diseases and metabolism
- Chronic Obstructive Pulmonary Disease (COPD) Research
The University of Queensland
2011-2024
Australian Regenerative Medicine Institute
2023
Monash University
2023
The University of Melbourne
2023
Murdoch Children's Research Institute
2023
Royal Children's Hospital
2023
Monash Children’s Hospital
2023
University of Maryland, Baltimore
2022
John Wiley & Sons (United States)
2022
Henry Ford Hospital
2017
ABSTRACT Yersinia pestis , the causative agent of plague, and enteropathogen pseudotuberculosis have nearly identical nucleotide similarity yet cause markedly different diseases. To investigate this conundrum to study pathogenicity, we developed a high-density oligonucleotide array-based modification signature-tagged mutagenesis (STM). Y. YPIII mutants constructed with tagged transposons were evaluated in murine yersiniosis infection model. The DNA tags amplified using biotinylated primers...
Studies of exercise in patients with myasthenia gravis (MG) are sparse. Balance strategy training (BST) multimodal has proven efficacy adults for enhancing balance and functional mobility. This prospective study aims to determine if BST improves ability people MG.Seven individuals MG participated a 16-session workstation intervention. Repeated measures (pre/post-intervention 4-week follow-up) consisting quantitative score (QMG), 6-minute walk test (6MWT), timed up go (TUG) dual task...
Student-led clinics are becoming more prominent as educators seek alternate models of clinical education for health professionals. The purpose this study was to evaluate healthcare students' experiences an interprofessional student-led clinic clients with neurological conditions. Thirteen students representing occupational therapy, physiotherapy, and speech pathology were recruited the study. A sequential mixed-methods evaluation employed results from Interprofessional Education Scale focus...
Many people with multiple sclerosis experience problems walking, which can make daily activities difficult and often leads to falls. Foot sensation plays an important role in keeping the body balanced whilst walking; however, have poor on soles of their feet. Wearing a specially designed shoe insole, enhances plantar sensory information, could help walk better. This study will explore whether long-term wear textured insole improve walking sclerosis.
Background Group and home‐based exercises to improve function in people with multiple sclerosis (MS) are common but have little underpinning evidence. Objective To determine the comparative effectiveness of a center‐based group versus individual 8‐week exercise program gait balance MS. Design Prospective, randomized controlled trial. Setting Community program. Participants Fifty MS were completed allocated intervention (n = 26 center, n 24 home), 47 post‐assessment 44 follow‐up assessment....
There is little evidence of the concurrent validity commercially available wrist-worn long battery life activity monitors to measure steps in older adults at slow speeds and with real-world challenges. Forty aged over 60 years performed a treadmill protocol four speeds, 50-m indoor circuit, 200-m outdoor circuit environmental challenges while wearing Garmin Vivofit®4, activPAL3™, chest-worn camera angled feet. The Vivofit®4 showed high intraclass correlation coefficients2,1 (.98-.99) low...
Research has consistently shown cervical kinematic impairments in subjects with persistent neck pain (NP). It could be reasoned that those vestibular pathology (VP) may also have altered kinematics since stimulation via head movement can cause dizziness and visual disturbances. However, this not been examined to date. This pilot study investigated changes between asymptomatic control, NP VP using a Virtual Reality (VR) system. was hypothesised there would subjects, which might associated...
Purpose Physical activity is an important modifiable determinant of health. There has been a historical aversion to movement in people with myasthenia gravis (MG) due the pathophysiology disease, however, research suggests engagement physical safe and does not exacerbate symptoms. are currently no studies investigating qualitative perspectives MG on activity. The aim this study was explore perceptions activity, barriers, enablers, participants' experiences advice from health professionals.
Abstract Background Clinical guidelines recommend initiation of antiviral therapy as soon possible for patients hospitalized with confirmed or suspected influenza. Methods A multicenter US observational sentinel surveillance network prospectively enrolled adults (aged ≥18 years) laboratory-confirmed influenza at 24 hospitals during October 1, 2022–July 21, 2023. multivariable proportional odds model was used to compare peak pulmonary disease severity (no oxygen support, standard supplemental...
Multiple sclerosis (MS) is a neurodegenerative pathology that affects young people in the prime of their lives, often having an impact on motor tasks such as walking, which subsequently participation daily activities. The symptoms caused by MS are highly variable, and rehabilitation strategies, focus movements exercises to improve or function, variable success.The aim this article summarise how non-motor have walking ability with MS, may vary across disability levels.A variety common early...
AbstractAbstractPurpose Although allied health services are important adjuncts to medical care for people with myasthenia gravis (MG), the underutilisation of these is not well understood within Australian context. It critical explore patients' perceptions develop that meet consumer needs. This study, therefore, sought obtain insight into MG patients’ perspectives and experiences, in addition outcomes, accessing services.Materials methods Thirteen adults participated semi-structured...
To investigate the immediate effects of wearing novel sensory-stimulating textured insoles on balance and gait in 41 people with multiple sclerosis (pwMS).Assessments (firm/foam surface; eyes open/closed) walking (when negotiating even/uneven surfaces) were performed insoles, smooth shoes only, barefoot. Outcome measures centre pressure (CoP) movement during standing (elliptical area, sway path velocity) spatiotemporal patterns (stride/step width, stride time, double-limb support length,...
Despite improvements in the medical management of myasthenia gravis (MG) recent years, patients continue to report poor health and wellbeing outcomes such as high levels fatigue, reduced quality life (QoL), walking limitation lowered balance confidence. Physical activity has been shown be associated with these other populations, however, there limited research adults MG.To describe physical sedentary behaviour MG explore associations between behaviours QoL, confidence limitation.A...
Purpose: This study explored experiences of bulbar (speech, voice and swallowing) symptoms in Australian adults with Myasthenia Gravis (MG), the relationship between these community participation quality-of-life. Further, it examined access to speech-language pathology (SLP) services, awareness perceptions SLP's role.Method: A cross-sectional mixed methods online survey collected data using researcher-designed questions patient-reported outcome measures (PROMs) including Dysarthria Impact...
<h2>Abstract</h2> This study aimed to explore how people with myasthenia gravis experience impairments in vision, dizziness, hearing, and fatigue, these relate balance confidence, community participation, health-related quality of life. Additionally, this investigated the utilisation perception allied health role managing Australian context. Visual hearing impairments, along were found be correlated life participation varying degrees, while visual impairment dizziness confidence. Perception...