A5050359821- Luminescence and Fluorescent Materials
- Lipid Membrane Structure and Behavior
- Molecular Sensors and Ion Detection
- Molecular Junctions and Nanostructures
- Fiber-reinforced polymer composites
- Electronic Packaging and Soldering Technologies
- Supramolecular Self-Assembly in Materials
- Photochromic and Fluorescence Chemistry
- Force Microscopy Techniques and Applications
- Semiconductor Lasers and Optical Devices
- 3D IC and TSV technologies
- Photoreceptor and optogenetics research
- Porphyrin and Phthalocyanine Chemistry
- Crystallography and molecular interactions
- Neural Networks and Reservoir Computing
- Photochemistry and Electron Transfer Studies
- Photonic and Optical Devices
- Advanced Fiber Laser Technologies
- Supramolecular Chemistry and Complexes
- Cellular transport and secretion
McGill University
2024
Eindhoven University of Technology
2023
University of Geneva
2018-2021
National Academy of Sciences of Ukraine
2019
Institute of Organic Chemistry
2019
Abstract Bent N,N′‐diphenyl‐dihydrodibenzo[a,c]phenazine amphiphiles are introduced as mechanosensitive membrane probes that operate by an unprecedented mechanism, namely, unbending in the excited state opposed to previously reported untwisting ground and twisting state. Their dual emission from bent or “closed” planarized “open” states is shown discriminate between micelles water monomers solid‐ordered (S o ), liquid‐disordered (L d ) bulk membranes. The dual‐emission spectra cover enough...
The combination of catalysis and transport across lipid bilayer membranes promises directional access to a solvent-free structured nanospace that could accelerate, modulate, and, at best, enable new chemical reactions. To elaborate on these expectations, anion with pnictogen tetrel bonds are combined polyether cascade cyclizations into bioinspired cation transporters. Characterized separately, synergistic transporters very high activity identified. Combined for in membranes, found occur...
Abstract Planarizable push–pull probes have been introduced to demonstrate physical forces in biology. However, the donors and acceptors needed polarize mechanically planarized are incompatible with their twisted resting state. The objective of this study was overcome “flipper dilemma” chalcogen‐bonding cascade switches that turn on only response mechanical planarization probe. This concept is explored by molecular dynamics simulations as well chemical double‐mutant cycle analysis. Cascade...
Abstract Bent N,N′‐diphenyl‐dihydrodibenzo[a,c]phenazine amphiphiles are introduced as mechanosensitive membrane probes that operate by an unprecedented mechanism, namely, unbending in the excited state opposed to previously reported untwisting ground and twisting state. Their dual emission from bent or “closed” planarized “open” states is shown discriminate between micelles water monomers solid‐ordered (S o ), liquid‐disordered (L d ) bulk membranes. The dual‐emission spectra cover enough...
Viscoadaptation is an essential process in natural cells, where supramolecular interactions between cytosolic components drive adaptation of the cellular mechanical features to regulate metabolic function. This important relationship properties and function has until now been underexplored artificial cell research. Here, we have created platform that exploits internal display viscoadaptive behavior. As material mimic component these employed a pH-switchable hydrogelator based on...
Abstract Planarizable push–pull probes have been introduced to demonstrate physical forces in biology. However, the donors and acceptors needed polarize mechanically planarized are incompatible with their twisted resting state. The objective of this study was overcome “flipper dilemma” chalcogen‐bonding cascade switches that turn on only response mechanical planarization probe. This concept is explored by molecular dynamics simulations as well chemical double‐mutant cycle analysis. Cascade...
Design, synthesis and evaluation of push-pull N,N′-diphenyl-dihydrodibenzo[a,c]phenazines are reported. Consistent with theoretical predictions, donors acceptors attached to the bent mechanophore shown shift absorption maxima either red or blue, depending on their positioning in chromophore. Redshifted excitation fluorophores is reflected redshifted emission both planar excited states. The intensity ratios dual more less polar solvents imply that excited-state (ES) planarization decelerates...
The acceptor strength of the 1,2-diphenyl-3,5-pyrazolidinedione residue is re-evaluated based on spectral-fluorescent properties donor–acceptor dyes. Low fluorescence title compounds explained by low-lying forbidden ππ*-state.