A5101826361- Mechanical and Optical Resonators
- Force Microscopy Techniques and Applications
- Advanced MEMS and NEMS Technologies
- Advanced Frequency and Time Standards
- Advanced Fiber Laser Technologies
- Advanced Thermodynamics and Statistical Mechanics
- Thermal properties of materials
- Orbital Angular Momentum in Optics
- Photonic and Optical Devices
- Cold Atom Physics and Bose-Einstein Condensates
- Advancements in Semiconductor Devices and Circuit Design
- Pulsars and Gravitational Waves Research
- Geophysics and Sensor Technology
- Quantum Electrodynamics and Casimir Effect
- Stellar, planetary, and galactic studies
- Atomic and Subatomic Physics Research
- Computational Drug Discovery Methods
- Alzheimer's disease research and treatments
- Plant Ecology and Taxonomy Studies
- Astro and Planetary Science
- Cholinesterase and Neurodegenerative Diseases
- Astronomical Observations and Instrumentation
École Normale Supérieure de Lyon
2013-2021
Université Claude Bernard Lyon 1
2013-2021
Centre National de la Recherche Scientifique
2013-2021
Universidad de Aysén
2021
Universidad de Santiago de Chile
2008-2017
University of Chile
2017
Laboratoire de Physique de l'ENS de Lyon
2013-2015
Université de Lyon
2013
Alzheimer's disease is a common tauopathy where fibril formation and aggregates are the hallmark of disease. Efforts targeting amyloid-β plaques have succeeded to remove but failed in clinical trials improve cognition; thus, current therapeutic strategy at preventing tau aggregation. Here, we demonstrated that four phenolic diterpenoids rosmarinic acid inhibit fibrillization. Since, was most active compound, observe morphological changes atomic force microscopy images after treatment. Hence,...
In optical detection setups to measure the deflection of micro-cantilevers, part sensing light is absorbed, heating mechanical probe. We present experimental evidences a frequency shift resonant modes cantilever when power measurement set-up increased. This signature temperature rise, and presents dependence on mode number. An analytical model derived take into account profile along cantilever, it shows that shifts are given by an average weighted local curvature for each mode. apply this...
In recent years, an increasing number of devices and experiments are shown to be limited by mechanical thermal noise. particular, subhertz laser frequency stabilization gravitational wave detectors that able measure fluctuations ${10}^{\ensuremath{-}18}\text{ }\text{ }\mathrm{m}/\sqrt{\mathrm{Hz}}$ or less being noise in the dielectric coatings deposited on mirrors. this paper, we present a new measurement low absorption microcantilevers, compare it with results obtained from loss...
In this article, we present a deflection measurement setup for Atomic Force Microscopy (AFM). It is based on quadrature phase differential interferometer: measure the optical path difference between laser beam reflecting above cantilever tip and reference static base of sensor. A design with very low environmental susceptibility another allowing calibrated measurements wide spectral range are described. Both enable high resolution (down to $\SI{2.5E-15}{m/\sqrt{Hz}}$), illustrated by thermal...
We study the mechanical fluctuations of a micrometer sized silicon cantilever subjected to strong heat flow, thus having highly non-uniform local temperature. In this non-equilibrium steady state, we show that are equivalent thermal noise at equilibrium around room temperature, while its mean temperature is several hundred degrees higher. Changing dissipation by adding coating cantilever, recover expected rise with Our work demonstrates inhomogeneous mechanisms can decouple amplitude from...
When heated, micro-resonators present a shift of their resonance frequencies. We study specifically silicon cantilevers heated locally by laser absorption, and evaluate theoretically experimentally temperature profile its interplay with the mechanical resonances. enhanced version our earlier model [F. Aguilar Sandoval et al., J. Appl. Phys. 117, 234503 (2015)] including both elasticity geometry dependency, showing that latter can account for 20% observed first flexural mode. The description...
An interferometric method is implemented in order to accurately assess the thermal fluctuations of a micro-cantilever sensor liquid environments. The power spectrum density (PSD) together with Sader's model cantilever allow for indirect measurement viscosity good accuracy. quality deflection signal and characteristic low noise instrument detection corrections drawbacks due both shape irregularities uncertainties on position laser spot at fluctuating end cantilever. Variation below 0.03...
This paper demonstrates that it is possible to trap and release a super paramagnetic micro bead by fixing three beads in triangular array at the sensitive end of cantilever, simply switching on/off an external magnetic field.To provide evidence this principle we attached free single DNA molecule has been previously fixed other glass surface, using standard sample preparation protocol tweezers assays.The process reversible which preserves integrity tethered molecule, local force applied over...
Abstract A simple optical technique consisting in the rotation of Glan–Thompson polarizers is applied to independently vary and control power cooling laser repumping experiments 87Rb. For our experimental conditions, which include initial powers approximately 48 mW (for each laser), it was observed that atom cloud still visible after reducing ∼10 while keeping at its level. On other hand, maintained visibility ∼103 µW excitation In both cases variation lasers achieved without altering...
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In recent years an increasing number of devices and experiments are shown to be limited by mechanical thermal noise. particular sub-Hertz laser frequency stabilization gravitational wave detectors, that able measure fluctuations 10 <sup xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink">-18</sup> m/√(Hz) or less, being noise in the dielectric coatings deposited on mirrors. We present a novel technique structural relaxation analysis based direct...
A cloud of cold 85Rb atoms was recently observed for the first time in Chile a magneto optical trap using Rb getter. We also cooling and trapping 87Rb isotope. This experience represents preliminary result an ongoing effort to promote experimental research field quantum optics Chile.