A5100462344- Advanced MRI Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Atomic and Subatomic Physics Research
- Medical Imaging Techniques and Applications
- Sperm and Testicular Function
- Advanced X-ray and CT Imaging
- Reproductive Biology and Fertility
- Cardiac Imaging and Diagnostics
- Monoclonal and Polyclonal Antibodies Research
- Pulsars and Gravitational Waves Research
- Advanced Frequency and Time Standards
- Semiconductor materials and devices
- MRI in cancer diagnosis
- Ovarian function and disorders
- Advancements in Semiconductor Devices and Circuit Design
- Functional Brain Connectivity Studies
- Glycosylation and Glycoproteins Research
- Effects of Radiation Exposure
- Electronic and Structural Properties of Oxides
- Galectins and Cancer Biology
- Pregnancy and preeclampsia studies
- Microbial Fuel Cells and Bioremediation
- Autopsy Techniques and Outcomes
- Immune Response and Inflammation
- Aldose Reductase and Taurine
Wuhan University of Technology
2025
Beijing Normal University
2023
Peking University First Hospital
2023
Peking University
2023
Chinese Academy of Medical Sciences & Peking Union Medical College
2021
Cornell University
1995-2020
Weill Cornell Medicine
2017-2020
Henan University
2018
Henan Provincial People's Hospital
2018
Second Military Medical University
2017
This paper describes the design principles and fabrication process of metal nanocrystal memories. The advantages nanocrystals over their semiconductor counterparts include higher density states, stronger coupling with channel, better size scalability, freedom engineering work functions to optimize device characteristics. One-dimensional (1-D) analyses are provided illustrate concept function engineering, both in direct-tunneling F-N-tunneling regimes. A self-assembled formation by rapid...
Purpose The aim of the 2016 quantitative susceptibility mapping (QSM) reconstruction challenge was to test ability various QSM algorithms recover underlying from phase data faithfully. Methods Gradient‐echo images a healthy volunteer acquired at 3T in single orientation with 1.06 mm isotropic resolution. A reference map provided, which computed using tensor imaging algorithm on 12 head orientations. Susceptibility maps calculated were compared against map. Deviations quantified following...
Purpose To develop a quantitative susceptibility mapping (QSM) method with consistent zero reference using minimal variation in cerebrospinal fluid (CSF) susceptibility. Theory and Methods The ventricular CSF was automatically segmented on the map. An L 2 ‐regularization used to enforce homogeneity within region, averaged as reference. This regularization for added model prior QSM (morphology enabled dipole inversion [MEDI]). Therefore, proposed referred MEDI+0 compared MEDI numerical...
This paper describes the electrical characteristics of metal nanocrystal memory devices continued from previous [see ibid., vol. 49, p. 1606-13, Sept. 2002]. Devices with Au, Ag, and Pt nanocrystals working in F-N tunneling regime have been investigated compared Si devices. With hot-carrier injection such as programming mechanism, retention time up to 10/sup 6/ s has observed 2-bit-per-cell storage capability demonstrated analyzed. The concern possible contamination is also addressed by...
Purpose To investigate systematic errors in traditional quantitative susceptibility mapping (QSM) where background field removal and local inversion (LFI) are performed sequentially, to develop a total (TFI) QSM method reduce these errors, improve quality the presence of large differences. Theory Methods The proposed TFI is single optimization problem which simultaneously estimates fields, preventing error propagation from QSM. increase computational speed, new preconditioner introduced...
Deep learning (DL) is increasingly used to solve ill-posed inverse problems in medical imaging, such as reconstruction from noisy and/or incomplete data, DL offers advantages over conventional methods that rely on explicit image features and hand engineered priors. However, supervised DL-based may achieve poor performance when the test data deviates training for example, it has pathologies not encountered data. Furthermore, reconstructions do always incorporate underlying forward physical...
The effects of commercially available amino acids, referred to as Eagle's non-essential acids (NEAA) and essential (EAA), on the development bovine embryos produced by in-vitro maturation fertilization (IVF) in a simple modified protein-free KSOM medium containing polyvinyl alcohol (PVA) were studied. Embryos IVF cultured an atmosphere 5% O2, CO2 90% N2 at 39 degrees C for first 40-44 h KSOM. Then with four or more cells KSOM-PVA different another 6 days experiments 1 2. In experiment 3,...
Streamer properties such as their velocity, diameter, intensity and density, can be obtained by analysis of temporal spatial resolved ICCD imaging. In this paper, experimental results on streamer generation propagation a function several high-voltage pulse reactor parameters are described. Experiments were performed large scale wire–plate in ambient air. The set-up allows for independent variation the over wide ranges. minimum gate time camera is 5 ns, allowing high resolution. triggered...
<h3>BACKGROUND AND PURPOSE:</h3> A hyperintense rim on susceptibility in chronic MS lesions is consistent with iron deposition, and the purpose of this study was to quantify iron-related myelin damage within these as compared those without rim. <h3>MATERIALS METHODS:</h3> Forty-six patients had 2 longitudinal quantitative mapping automatic zero reference scans a mean interval 28.9 ± 11.4 months. Myelin water fraction by using fast acquisition spiral trajectory T2 prep obtained at second time...
Soft actuators are valued for their adaptability and diverse applications but often face challenges like slow response, high activation energy, energy consumption. To address these issues, we developed a graphene-assembled film (GAF) via the redox method, characterized by thermal conductivity, stiffness. Using GAF as photothermal electrothermal driver, engineered sandwich-structured metamaterial (SSM) combining two polymers with vastly different expansion coefficients. The SSM achieved rapid...
Affibody molecules are a class of scaffold proteins being developed into generalizable approach to targeting tumors. Many 3-helix–based have shown excellent in vivo properties for tumor imaging and therapy. By truncating one α-helix that is not responsible receptor recognition the maturating protein affinity through synthetic strategies, we successfully identified our previous research several small 2-helix with binding affinities human epidermal growth factor type 2 (<i>HER2</i>). With...
Background Accurate measurement of the liver iron concentration (LIC) is needed to guide iron‐chelating therapy for patients with transfusional overload. In this work, we investigate feasibility automated quantitative susceptibility mapping (QSM) measure LIC. Purpose To develop a rapid, robust, and QSM clinical practice. Study Type Prospective. Population 13 healthy subjects 22 patients. Field Strength/Sequences 1.5 T 3 T/3D multiecho gradient‐recalled echo (GRE) sequence. Assessment Data...
Purpose To demonstrate the feasibility of in vivo quantitative susceptibility mapping (QSM) cardiac MRI and to show that mixed‐venous oxygen saturation (SvO 2 ) can be measured non‐invasively using QSM. Methods Electrocardiographic‐gated multi‐echo 2D gradient echo data were collected at 1.5 T from 14 healthy volunteers during successive breath‐holds. Phase wraps fat chemical shift removed a graph‐cut‐based phase analysis IDEAL an iterative approach. The large range air lungs blood heart was...
Studies were designed to evaluate bull sperm motility and membrane integrity following exposure Tyrode's solution varying in osmolality from 100 1537 mOsm. Congo red bisbenzimide (HOECHST 33258) stains used distinguish between with intact versus disrupted plasma membranes. Sperm was subjectively evaluated. No significant differences found motile unstained (sperm membranes) solutions nearly physiologic osmolalities 200 300 However, 100- 150-mOsm solutions, the percentage of (5 19%),...
ABSTRACT BACKGROUND AND PURPOSE Quantitative susceptibility mapping (QSM) of the brain has become highly reproducible and applications in an expanding array diseases. To translate QSM from bench to bedside, it is important automate its reconstruction immediately after data acquisition. In this work, a server system that automatically reconstructs exchange images with scanner using DICOM standard demonstrated multi‐site, multi‐vendor reproducibility study large, single‐site, multi‐scanner...
Differential blood oxygenation between left (LV) and right ventricles (RV; ΔSaO
Purpose To develop a nonlinear preconditioned total field‐inversion algorithm using the MEDI toolbox (MEDInpt) for robust QSM of carotid plaques and evaluate its performance in comparison with local (STI Suite) previously applied to QSM. Methods Numerical simulation vivo were performed compare MEDInpt STI Suite algorithms. Multicontrast MRI was used as reference standard detecting calcified plaque intraplaque hemorrhage (IPH). A 5 healthy volunteers 11 patients at least one significant...
Ionizing radiation causes severe damage to human body, and normal tissue toxicity in cancer radiotherapy also limits its further application. It is urgently required develop safe effective radioprotector. Our previous study has shown that toll like receptor 4 (TLR4) was dispensable for basal resistance. However, of traditional agonist lipopolysaccharide the clinical In present study, we demonstrated monophosphoryl lipid A (MPLA), a potent TLR4 with low toxicity, effectively attenuated injury...
The small intestine is one of the most sensitive organs to irradiation injury, and development high effective radioprotectants especially with low toxicity for intestinal radiation sickness urgently needed. Monophosphoryl lipid A (MPLA) was found be radioprotective in our previous study, while its effect against injury remained unknown. In present we firstly determined apoptosis after according TUNEL assay. Subsequently, adopted immunofluorescence technique assess expression levels different...
Quantitative susceptibility mapping (QSM) of human spinal vertebrae from a multi‐echo gradient‐echo (GRE) sequence is challenging, because comparable amounts fat and water in the make it difficult to solve nonconvex optimization problem fat‐water separation (R2*‐IDEAL) for estimating magnetic field induced by tissue susceptibility. We present an in‐phase (IP) echo initialization R2*‐IDEAL QSM vertebrae. Ten healthy subjects were recruited spine MRI. A 3D GRE was implemented acquire out‐phase...