A5029725719- Advanced MRI Techniques and Applications
- Advanced Neuroimaging Techniques and Applications
- Functional Brain Connectivity Studies
- Medical Imaging Techniques and Applications
- Fetal and Pediatric Neurological Disorders
- Cardiac Imaging and Diagnostics
- MRI in cancer diagnosis
- Advanced X-ray and CT Imaging
- Neural and Behavioral Psychology Studies
- Parkinson's Disease Mechanisms and Treatments
- Traumatic Brain Injury Research
- Attention Deficit Hyperactivity Disorder
- Cerebrovascular and Carotid Artery Diseases
- Neurological disorders and treatments
- Transportation Planning and Optimization
- Urban Transport and Accessibility
- Family and Disability Support Research
- Atomic and Subatomic Physics Research
- Musculoskeletal pain and rehabilitation
- Energy, Environment, and Transportation Policies
- Peripheral Artery Disease Management
- Neonatal and fetal brain pathology
- Surgical Simulation and Training
- EEG and Brain-Computer Interfaces
- Cerebrospinal fluid and hydrocephalus
University of Canterbury
2006-2024
Yale University
2019-2023
Maine Department of Marine Resources
2023
University of North Texas
2019-2021
Malden Public Schools
2018-2021
Hudson Institute
2018-2021
Imaging Center
2004-2021
John Wiley & Sons (United States)
2019-2020
University of Illinois Urbana-Champaign
2020
Counseling Center
2019-2020
<b>Background:</b> The classification of antineutrophil cytoplasmic antibody-associated vasculitis (AAV) and polyarteritis nodosa (PAN) for epidemiology studies is confusing. existing schemes such as American College Rheumatology (ACR) criteria, Chapel Hill Consensus Conference (CHCC) definitions Lanham criteria produce overlapping conflicting classifications, making it difficult to compare incidence figures. <b>Aim:</b> To develop a consensus method using these epidemiological permit...
<h3>Objective:</h3> To establish the diagnostic accuracy of Montreal Cognitive Assessment (MoCA) when screening externally validated cognition in Parkinson disease (PD), by comparison with a PD-focused test (Scales for Outcomes disease–Cognition [SCOPA-COG]) and standardized Mini-Mental State Examination (S-MMSE) as benchmarks. <h3>Methods:</h3> A convenience sample 114 patients idiopathic PD 47 healthy controls was examined movement disorders center. The 21 dementia (PD-D) were diagnosed...
Many studies have linked activity in a frontostriatal network with the capacity to suppress inappropriate thoughts and actions, but relatively few examined role of connectivity between these structures. Here, we use diffusion tensor imaging assess 21 subjects (ages 7–31 years). Fifteen were tested on go/no-go task, where they responded button press visual stimulus inhibited response second infrequent stimulus. An automated fiber tracking algorithm was used delineate white matter fibers...
Objective Mild cognitive impairment and dementia are common non-motor features of Parkinson's disease (PD). The aim this study was to characterise grey matter changes associated with clearly defined stages in PD using structural MRI. Methods 96 subjects were classified detailed testing as normal cognition (PD-N, n=57), mild (PD-MCI, n=23) or (PD-D, n=16); 34 controls matched for mean age sex ratio also participated. Grey volume differences evaluated voxel based morphometry segments derived...
Head motion represents one of the greatest technical obstacles in magnetic resonance imaging (MRI) human brain. Accurate detection artifacts induced by head requires precise estimation movement. However, estimates may be corrupted due to main field fluctuations generated body motion. In current report, we examine multiband resting state functional connectivity MRI (rs-fcMRI) data from Adolescent Brain and Cognitive Development (ABCD) Study comparison 'single-shot' datasets. We show that...
There is a need for objective imaging markers of Parkinson's disease status and progression. Positron emission tomography single photon computed studies have suggested patterns abnormal cerebral perfusion in as potential functional biomarkers. This study aimed to identify an arterial spin labelling magnetic resonance-derived network accessible, non-invasive alternative. We used pseudo-continuous measure grey matter 61 subjects with range motor cognitive impairment, including patients...
To characterize different stages of Parkinson disease (PD)-related cognitive decline using diffusion tensor imaging (DTI) and investigate potential relationships between cognition microstructural integrity primary white matter tracts.Movement Disorder Society criteria were used to classify 109 patients with PD as having normal (PD-N, n = 63), mild impairment (PD-MCI, 28), or dementia (PD-D, 18), compared 32 matched controls. DTI indices assessed across groups tract-based spatial statistics,...
There is growing interest in identifying Parkinson's disease (PD) patients with mild cognitive impairment (PD-MCI), but widely disparate criteria have been used. We assessed 143 PD and 50 matched controls on 20 measures across 4 domains (executive function, attention working memory, learning visuoperception). Twenty-four met for dementia (PD-D); nondementia were classified as either normal cognition or MCI 12 neuropsychological criteria. compared the influence of these distribution global...
<h3>Importance</h3> A total of 25.7 million children in the United States are classified as overweight or obese. Obesity is associated with deficits executive function, which may contribute to poor dietary decision-making. Less known about associations between being obese and brain development. <h3>Objective</h3> To examine whether body mass index (BMI) thickness cerebral cortex cortical mediates association BMI function children. <h3>Design, Setting, Participants</h3> In this...
Maintaining alertness is critical for safe and successful performance of most human activities.Consequently, microsleeps during continuous visuomotor tasks, such as driving, can be very serious, not only disrupting but sometimes leading to injury or death due accidents.We have investigated the neural activity underlying behavioral -brief (0.5-15 s) episodes complete failure respond accompanied by slow eye-closures -and EEG theta drowsiness in a task.Twenty healthy normally-rested...
<h3>SUMMARY:</h3> On the basis of animal models, glymphatic flow disruption is hypothesized to be a factor in development Alzheimer9s disease. We report first quantitative study man, combining intrathecal administration gadobutrol with serial T1 mapping produce contrast concentration maps up 3 days postinjection, demonstrating performing using techniques described feasibility and providing data on pharmacokinetics.
Abstract The Adolescent Brain Cognitive Development Study (ABCD), a 10 year longitudinal neuroimaging study of the largest population based and demographically distributed cohort 9-10 olds (N=11,877), was designed to overcome reproducibility limitations prior child mental health studies. Besides fantastic wealth research opportunities, extremely large size ABCD data set also creates enormous storage, processing, analysis challenges for researchers. To ensure privacy safety, researchers are...
Working memory function changes across development and varies individuals. The patterns of behavior brain that track individual differences in working during human development, however, are not well understood. Here, we establish associations between memory, other cognitive abilities, functional MRI (fMRI) activation data from over 11,500 9- to 10-year-old children (both sexes) enrolled the Adolescent Brain Cognitive Development (ABCD) Study, an ongoing longitudinal study United States....
To study the short-term effects of vagus nerve stimulation (VNS) on brain activation and cerebral blood flow by using functional magnetic resonance imaging (fMRI).Five patients (three women, two men; mean age, 35.4 years) who were treated for medically refractory epilepsy with VNS, underwent fMRI. All had a nonfocal MRI. The VNS was set at 30 Hz, 0.5-2.0 mA intervals s off, during which fMRI performed. Statistical parametric mapping (SPM) used to determine significant areas or inhibition...
The goal of this study was to use diffusion-tensor magnetic resonance (MR) imaging define the location and organization corticospinal tracts (CSTs) in posterior limb internal capsule (PLIC). Institutional Review Board approved study, informed consent obtained from all subjects. Eight volunteers two patients with brain tumor were imaged at 3 T. All CSTs found lie a compact area one part PLIC: If PLIC is divided into four equal quarters anterior posterior, CST shown be third quarter. Seventeen...
The presence and extent of structural changes in the brain as a consequence Parkinson's disease (PD) is still poorly understood. High-resolution 3-tesla T1-weighted magnetic resonance images sixty-five PD 27 age-matched healthy control participants were examined. Putamen, caudate, intracranial volumes manually traced axial plane 3D reconstructed images. Striatal nuclei normalized to volume for statistical comparison. Disease status was assessed using Unified Rating Scale Hoehn Yahr scale....
Cannabis is the most commonly used illicit drug in adolescence. Heavy use associated with deficits on a broad range of cognitive functions and heavy during adolescence may impact development gray white matter.To examine differences intrinsic brain activity connectivity cannabis dependence using whole-brain voxelwise approaches.Adolescents admitted to drug-treatment facility for (n = 17) age-matched controls 18) were compared measure oscillations low-frequency blood oxygen level-dependent...
The diagnosis of multiple sclerosis (MS) presently relies on radiographic assessments imperfect specificity. Recent data using T2* methodology for the detection "central vessel sign" (CVS) in MS lesions suggests this novel MRI technique may distinguish from other disorders. Our aim was to determine if evaluation CVS 3T FLAIR* differentiates migraine.Patients with or migraine and a prior brain demonstrating at least two hyperintense ≥3 mm were recruited. Exclusion criteria included any...