İlhami Kovanlıkaya

ORCID: 0000-0001-6339-9862
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About
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Research Areas
  • Advanced MRI Techniques and Applications
  • Advanced Neuroimaging Techniques and Applications
  • Glioma Diagnosis and Treatment
  • MRI in cancer diagnosis
  • Radiomics and Machine Learning in Medical Imaging
  • Cerebrospinal fluid and hydrocephalus
  • Cardiac Imaging and Diagnostics
  • Brain Metastases and Treatment
  • Functional Brain Connectivity Studies
  • Medical Imaging Techniques and Applications
  • Multiple Sclerosis Research Studies
  • Intracerebral and Subarachnoid Hemorrhage Research
  • Radiopharmaceutical Chemistry and Applications
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Ultrasound Imaging and Elastography
  • Fetal and Pediatric Neurological Disorders
  • Peripheral Nerve Disorders
  • Brucella: diagnosis, epidemiology, treatment
  • Photoacoustic and Ultrasonic Imaging
  • Prostate Cancer Diagnosis and Treatment
  • Lanthanide and Transition Metal Complexes
  • Spinal Dysraphism and Malformations
  • Ultrasound and Hyperthermia Applications
  • Meningioma and schwannoma management
  • Neurological disorders and treatments

Cornell College
2023-2024

Weill Cornell Medicine
2017-2024

Cornell University
2015-2024

Presbyterian Hospital
2012-2022

New York Hospital Queens
2012-2022

NewYork–Presbyterian Hospital
2012-2022

University Radiology
2015

University of Miami
2014

Chinese University of Hong Kong
2013

Applied Multilayers (United Kingdom)
2013

Purpose To assess the reproducibility of brain quantitative susceptibility mapping (QSM) in healthy subjects and patients with multiple sclerosis (MS) on 1.5 3T scanners from two vendors. Materials Methods Ten volunteers 10 were scanned twice a scanner one vendor. The also 1.5T same vendor second Similar imaging parameters used for all scans. QSM images reconstructed using recently developed nonlinear morphology‐enabled dipole inversion (MEDI) algorithm L1 regularization. Region‐of‐interest...

10.1002/jmri.24943 article EN Journal of Magnetic Resonance Imaging 2015-05-09

Diffusion Tensor Imaging and Tractography of Median Nerve: Normative ValuesNeslihan Kabakci1, Bengi Gürses1, Zeynep Firat1, Ali Bayram1, Aziz Müfit Uluğ2 3, Arzu Kovanlikaya1 İlhami Kovanlikaya1Audio Available | Share

10.2214/ajr.07.2423 article TR American Journal of Roentgenology 2007-09-20

Brain retraction systems are frequently required to achieve surgical exposure of deep-seated brain lesions. Spatula-based can be associated with injury the cortex and deep white matter, particularly adjacent sharp edges, which result in uneven pressure on parenchyma over course a long operation. The use tubular retractor has been proposed as method overcome these limitations. There have no studies assessing degree retractors. METHODS :Twenty patients were retrospectively identified at Weill...

10.3171/2015.4.jns142576 article EN Journal of neurosurgery 2015-10-02

Resected brain metastases have a high rate of local recurrence without adjuvant therapy. Adjuvant whole-brain radiotherapy (WBRT) remains the standard care with control > 90%. However, WBRT is delivered over 10-15 days, which can delay other therapy and associated acute long-term toxicities. Permanent cesium-131 ((131)Cs) implants be used at time metastatic resection, thereby avoiding need for any additional The authors evaluated safety, feasibility, efficacy novel therapeutic approach...

10.3171/2014.3.jns131140 article EN Journal of neurosurgery 2014-05-02

To assess the effects of low-dose acetazolamide treatment on volumetric MRI markers and clinical outcome in idiopathic normal-pressure hydrocephalus (iNPH).We analyzed gait measures from 8 patients with iNPH serial MRIs an institutional review board-approved imaging protocol who had been treated off-label (125-375 mg/day). studies included fluid-attenuated inversion recovery 3D T1-weighted high-resolution imaging. Automated analyses were employed to quantify each patient's ventricular,...

10.1212/wnl.0000000000000313 article EN Neurology 2014-03-15

<h3>BACKGROUND AND PURPOSE:</h3> A hyperintense rim on susceptibility in chronic MS lesions is consistent with iron deposition, and the purpose of this study was to quantify iron-related myelin damage within these as compared those without rim. <h3>MATERIALS METHODS:</h3> Forty-six patients had 2 longitudinal quantitative mapping automatic zero reference scans a mean interval 28.9 ± 11.4 months. Myelin water fraction by using fast acquisition spiral trajectory T2 prep obtained at second time...

10.3174/ajnr.a5482 article EN cc-by American Journal of Neuroradiology 2017-12-14

Purpose To investigate the magnetic susceptibility of intracerebral hemorrhages (ICH) at various stages by applying quantitative mapping (QSM). Materials and Methods Blood was measured serially using QSM after venous blood withdrawal from healthy subjects. Forty‐two patients who provided written consent were recruited in this Institutional Review Board‐approved study. Gradient echo resonance imaging (MRI) data 42 (17 females; 64 ± 12 years) with ICH processed QSM. The susceptibilities...

10.1002/jmri.25143 article EN Journal of Magnetic Resonance Imaging 2015-12-31

ABSTRACT BACKGROUND AND PURPOSE Ultrahigh‐field 7T promises more than doubling the signal‐to‐noise ratio (SNR) of 3T for magnetic resonance imaging (MRI), particularly MRI susceptibility effects induced by B 0 . Quantitative mapping (QSM) is based on deconvolving phase (or field) and would therefore benefit substantially from 7T. The purpose this work was to compare QSM performance at versus in an intrascanner test‐retest experiment with varying echo numbers (5 10 echoes). METHODS A...

10.1111/jon.12669 article EN Journal of Neuroimaging 2019-10-18

ABSTRACT BACKGROUND AND PURPOSE Telomerase reverse transcriptase (TERT) promoter mutations are associated with worse prognosis in glioblastoma. The purpose of this study was to evaluate whether TERT mutation status specific morphologic and quantitative imaging features. METHODS Twenty‐nine patients isocitrate dehydrogenase 1/2‐wildtype glioblastoma (13 TERT‐wildtype, 16 TERT‐mutated), who underwent preoperative magnetic resonance (MR) were included retrospective study. Qualitative phenotypes...

10.1111/jon.12596 article EN Journal of Neuroimaging 2019-01-15

Current radiologic diagnosis of normal pressure hydrocephalus (NPH) requires a subjective judgment whether lateral ventricular enlargement is disproportionate to cerebral atrophy based on visual inspection brain images. We investigated quantitative measurements volume and total cortical thickness (a correlate atrophy) could be used more objectively distinguish NPH from controls (NC), Alzheimer's (AD), Parkinson's disease (PD). Volumetric MRIs were obtained prospectively patients with...

10.1155/2012/718150 article EN cc-by Neurology Research International 2011-08-07

<h3>BACKGROUND AND PURPOSE:</h3> Accurate diagnosis of normal pressure hydrocephalus is challenging because the clinical symptoms and radiographic appearance NPH often overlap those other conditions, including age-related neurodegenerative disorders such as Alzheimer Parkinson diseases. We hypothesized that radiologic differences between AD/PD can be characterized by a robust objective MR imaging DTI technique does not require intersubject image registration or operator-defined regions...

10.3174/ajnr.a3368 article EN cc-by American Journal of Neuroradiology 2012-12-20

The objective was to identify changes in quantitative MRI measures patients with idiopathic normal pressure hydrocephalus (iNPH) occurring common after oral acetazolamide (ACZ) and external lumbar drainage (ELD) interventions.A total of 25 iNPH from two clinical sites underwent serial MRIs assessments. Eight received ACZ (125-375 mg/day) over 3 months 12 ELD for up 72 hours. Five clinically-stable who were scanned serially without interventions served as controls the component study....

10.1186/s12987-015-0004-z article EN cc-by Fluids and Barriers of the CNS 2015-04-01

BACKGROUND: Cesium-131 (Cs-131) brachytherapy is used to reduce local recurrence of resected brain metastases. To ensure dose homogeneity and risk radiation necrosis, interseed distance cavity volume must remain stable during delivery. OBJECTIVE: investigate the efficacy “seeds-on-a-string” technique with intracavitary fibrin glue in achieving stability. METHODS: We placed intraoperative Cs-131 30 cavities postresection Seeds-on-a-string were like barrel staves within glue. Serial magnetic...

10.1227/neu.0000000000000986 article EN Operative Neurosurgery 2015-08-26

Typical quantitative susceptibility mapping (QSM) reconstruction steps consist of first estimating the magnetization field from gradient-echo images, and then reconstructing map estimated field. The errors field-estimation may propagate into final QSM map, noise in no longer be zero-mean Gaussian noise, thus, causing streaking artifacts resulting QSM. A multiecho complex total inversion (mcTFI) method was developed to compute directly gradient echo images using an improved signal model that...

10.1002/mrm.28814 article EN Magnetic Resonance in Medicine 2021-05-24

We aimed to demonstrate the feasibility of whole brain oxygen extraction fraction (OEF) mapping for measuring lesion specific and regional OEF abnormalities in multiple sclerosis (MS) patients. In 22 MS patients 11 healthy controls (HC), neural tissue susceptibility ([Formula: see text]) maps were computed from MRI multi-echo gradient echo data. patients, 80 chronic active lesions with hyperintense rim on quantitative identified, mean [Formula: text] within core compared using linear...

10.1177/0271678x211048031 article EN other-oa Journal of Cerebral Blood Flow & Metabolism 2021-09-24

Quantitative susceptibility mapping (QSM) involves acquisition and reconstruction of a series images at multi-echo time points to estimate tissue field, which prolongs scan requires specific technique. In this paper, we present our new framework, called Learned Acquisition Reconstruction Optimization (LARO), aims accelerate the gradient echo (mGRE) pulse sequence for QSM. Our approach optimizing Cartesian k-space sampling pattern with deep network. Next, optimized was implemented in an mGRE...

10.1016/j.neuroimage.2023.119886 article EN cc-by-nc-nd NeuroImage 2023-01-17
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