Rhabdomyolysis (RB) is a syndrome characterised by decomposition of skeletal muscle that could be life threatening, so the identification biomarkers its severity help us in treatment. Creatine kinase (CK) usually taken as reference patients with RB order to stratify prognosis, however not probably most effective parameter.The present study was designed analyse specific features and mortality relation between creatinine, CK mortality.Retrospective cohort analysis among admitted San Pedro...

A simple and convenient one-pot synthesis of THF solutions high molecular weight poly(dichlorophosphazene) [NPCl(2)](n), or the (15)N isotopomer [(15)NPCl(2)](n), starting directly from PCl(5) NH(4)Cl (15)NH(4)Cl in a solution 1,2,4-trichlorobenzene presence sulfamic acid calcium sulfate dihydrate, is described. The [NPCl(2)](n) THF, which are obtained free poly(tetrahydrofuran) by preparing them K(2)CO(3), can be reacted with phenols, biphenols, even HO-CH(2)CF(3) K(2)CO(3) Cs(2)CO(3) to...

The polymer [NPCl2]n reacts with the functionalized biphenols bis(2-hydroxy-5-chlorophenyl)methane [(HOC6H3Cl)2CH2], bis(2-hydroxyphenyl) ketone [(HOC6H4)2CO], and [racemic(±)]-, [R(+)]-, or [S(−)]-1,1'-binaphthyl-2-ol [(HOC10H6C10H6OH)] (binaphthol), in THF, 1,4-dioxane presence of K2CO3 Cs2CO3 to give respectively spirocyclic phosphazene homopolymers [NP(O2C13H8Cl2)]n (1), [NP(O3C13H8)]n (2), (±)-[NP(O2C20H12)]n (5), (−)-[NP(O2C20H12)]n [(−)-5b], (+)-[NP(O2C20H12)]n [(+)-5b], some them...

Abstract The intrachain conformation, molecular structure and interchain assembly of isotactic ( R )‐poly(2,2′‐dioxy‐1,1′‐binaphthyl)phosphazene (P‐DBNP) both in the bulk state (I ) cast film (II) were studied by dynamics (MD) simulations models, as implemented a bias potential for analysis radial distribution function (RDF) obtained from large‐angle X‐ray scattering (LAXS) data. microscopic order extension polymer changed I to II, qualitatively shown shapes their experimentally measured RDF...

The reaction of a mixture [NPCl2]n and Cs2CO3 first with (R)-(+)-1,1'-binaphthyl-2,2'-diol (HO−C10H6−C10H6−OH) (binaphthol) subsequently phenol (HO−C6H5) in refluxing 1,4-dioxane gave the series optically active random copolymers {[NP(O2C20H12)]x[NP(OC6H5)2]1-x}n (2). Absolute molecular weight distributions radius gyration have been determined by size exclusion chromatography, using simultaneously multiangle light scattering differential refractive index detectors. dependence dimensions...

Abstract The molecular structure of the 2,2′‐dioxybiphenyl spirocyclic tetrachlorocyclotriphosphazene [N 3 P Cl 4 (O 2 C 12 H 8 )] ( ) was determined by X‐ray crystallography. and conformation in crystal are compared discussed with respect to those its analogues trispiro dispiro derivatives, ] 1 ), respectively. Both R S stereoisomers present lattice as arranged pairs ··· held together through sandwich‐type π‐stacking interactions (C7−C12)/(C7−C12)′ phenyl rings groups. polymer‐like assembly...

Steady-state and time-resolved fluorescence techniques are combined with theoretical molecular dynamics calculations applied to study the secondary structure of some random copolymers polyphophazenes containing phenoxy binaphthoxy chromophoric groups. Analysis excitation emission spectra, depolarization lifetimes suggested that 100% energy groups is transferred Subsequently, this migrates among along polymer chain. This migration produces a noticeable quenching fluorescence. The efficiency...

Poly(2,2′-dioxy-1,1′-biphenyl)phosphazene (I) is a weak base that can be reversibly protonated with HBF4 in acetone. Acidic degradation of poly(2,2′-dioxy-1,1′-biphenyl)phosphazene was experimentally performed using HBF4, HCl, and H2SO4 yielding the same polymer I lower molecular weights. The reaction takes place through protonation some skeletal bonds thus producing P+-NH bond, posterior rupture those by water. hydrolysis breaks only these bonds, leaving unaffected regular P−N bonds. degree...

Abstract The chiral cyclic triphosphazenes ( R )‐(–)‐[N 3 P (O 2 C 20 H 12 )(O 8 )Cl ] I ) and , )‐(–) [N )] II ), prepared by sequential substitution of P­ Cl 6 using )‐2,2′‐dihydroxy‐1,1′‐binaphthyl, 2,2′‐dihydroxy‐1,1′‐biphenyl Cs CO in acetone, have been investigated single‐crystal X‐ray diffraction, variable‐temperature NMR spectroscopy solution MM calculations under periodic boundary conditions the gas state. In both compounds only diastereomer corresponding to )‐biphenoxy...

The stereochemistry in solution of spirocyclophosphazenes 1–3 containing 2,2′-dioxybiphenyl groups, tris(2,2′-dioxybiphenyl)cyclotriphosphazene [N3P3(O2C12H8)3] (1) and the chloro derivatives [N3P3Cl2(O2C12H8)2] (2) [N3P3Cl4(O2C12H8)] (3), was studied using high field 1H, 13C 31P NMR spectroscopy (variable temperature experiments) combined with molecular dynamics (MD) simulations. ambient spectra, after full assignments, showed a unique set signals (four six for hydrogens carbons,...

The optically active ([α] = −192°) and mesomorphic (2θ 6°, d 14.7 Å) isotactic poly(2,2'-dioxy-1,1'-binaphthylphosphazene) R-(−)-[NP(O2C20H12)]n (1-R) (Mw 840 000) has a very high glass transition temperature, Tg (329 °C), can be thermally degraded between 100 160 °C to lower Mw distributions without decomposition. specific rotation in solution varied significantly with the Mw, wavelength, while of related random nonisotactic copolymer [NP(O2C20H12)]n (2-R/S) 750 000, [α] −50°), having...

<p style="text-align:justify">En infecci&oacute;n por SARS-CoV-2 (COVID-19), las manifestaciones m&aacute;s comunes son de v&iacute;as a&eacute;reas superiores; en casos complicados se presenta neumon&iacute;a intersticial bilateral, insuficiencia respiratoria aguda grave y falla org&aacute;nica m&uacute;ltiple que ameritan tratamiento hospitalario soporte ventilatorio puntas nasales o mascarilla, as&iacute; como ox&iacute;geno con flujo a presi&oacute;n alta intubaci&oacute;n orotraqueal...

Since the discovery of electronic conducting properties poly(acetylene), many other organic conjugated systems have been studied, having acquired increased importance in current technology. In this context, organometallic chemistry has played an important role catalytic version as well stoichiometric their synthesis. review, from first Ziegler catalyst used for Shirakawa to new palladium based catalysts which allow smooth cross-coupling reactions complex will be discussed. General mechanisms...

The structure and the assembly of tris-(2,2'-dioxy-binaphthyl)cyclotriphosphazene [(+)-[NP3(O2C20H12)3], DBNP, in solid amorphous state was studied using molecular dynamics (MD) including ad hoc quantum mechanically derived force field (FF) parameters, combination with energy dispersive X-ray diffraction (EDXD) technique. atom-atom radial distribution function (RDF) curve obtained through EDXD experiment revealed low intensity peaks not attributable to intramolecular distances single...

M21000461virus responsible for the current pandemic, which originated in Wuhan, China.Human coronaviruses are transmitted by direct contact with secretions and through aerosol droplets.Infected patients also excrete virus feces urine.

Abstract Solutions of a binaphthoxy phosphazene copolymer (containing chiral 2,2′‐dioxy‐1,1′‐binaphthyl units with 50% R and S configurations distributed along the chains) in N ‐methyl pyrrolidone were studied by means continuous flow experiments small amplitude oscillatory tests. A sudden viscosity decrease was observed polymer concentration range (39–40 wt %), evidencing liquid‐crystalline behavior. This has been confirmed other rheological methods which have demonstrated that, for...