A5081817728- Growth Hormone and Insulin-like Growth Factors
- Childhood Cancer Survivors' Quality of Life
- Adolescent and Pediatric Healthcare
- Autoimmune and Inflammatory Disorders Research
- Sexual Differentiation and Disorders
- Lipid metabolism and disorders
- Pharmacological Effects and Toxicity Studies
- Patient-Provider Communication in Healthcare
- Galectins and Cancer Biology
- Intestinal Malrotation and Obstruction Disorders
- Genetic Syndromes and Imprinting
- Genetics and Neurodevelopmental Disorders
- Neurogenetic and Muscular Disorders Research
- Diabetes and associated disorders
- Drug Transport and Resistance Mechanisms
- Immunodeficiency and Autoimmune Disorders
- Diabetes Treatment and Management
Icahn School of Medicine at Mount Sinai
2023-2024
Child Health and Development Institute
2023
To compare colesevelam hydrochloride (Cholestagel), a nonabsorbed hydrogel with bile acid-sequestering properties, placebo for its lipid-lowering efficacy, effects on laboratory and clinical safety parameters, the incidence of adverse events.Following diet lead-in periods, or was administered at 4 dosages (1.5, 2.25, 3.0, 3.75 g/d) 6 weeks morning evening meals to men women hypercholesterolemia (low-density lipoprotein cholesterol level >4.14 mmol/L [>160 mg/dL]). Patients returned clinic...
Abstract Background Resilience has been shown to be associated with better psychological outcomes and ability cope negative traumatic events in the healthcare setting. Therefore, this study, we aimed evaluate resilience its association disease activity health-related quality of life (HRQOL) children Systemic Lupus Erythematosus (SLE) Juvenile Idiopathic Arthritis (JIA). Findings Patients diagnoses SLE or JIA were recruited. We collected: demographic data, medical history physical...
Introduction We present the evolution of GHD in adolescent males with persistent growth failure, whom diagnosis was established after a second GH stimulation test (GST). Methods performed retrospective chart review children who presented for short stature (height less < 2SD mean/mid-parental height) and/or failure (sustained velocity 0 SD) to pediatric endocrinology at Mount Sinai Kravis Children’s Hospital, New York and had 2 GSTs. Data collected from electronic medical records were...
Two male patients, who presented at 13.5 and 13.9 years of age with growth failure short stature, were ultimately diagnosed isolated hormone deficiency (GHD). Patient 1 was first evaluated when his height declined from -0.67 SD to -1.3 SD. He had a peak (GH) concentration GH stimulation test (GHST) 16.9 ng/mL (16.9 μg/L) remained untreated. As puberty advanced, decreased further -1.65 A second GHST while serum testosterone 79 ng/dL (2.74 nmol/L) 5.4 (5.4 μg/L), consistent GHD. treated for...
Abstract Background: In this study, we aimed to evaluate resilience and its association with disease activity health-related quality of life (HRQOL) in children Systemic Lupus Erythematosus (SLE) Juvenile Idiopathic Arthritis (JIA). Findings: Using a cross-sectional design, patients diagnoses SLE or JIA were recruited between 8/2019 12/2022 pediatric rheumatology outpatient setting. At single study visit collected: demographic data, medical history physical examination, physician global...
Abstract Disclosure: S. Chimatapu: None. Sethuram: J. Samuels: M. Savage: R. Rapaport: Introduction: Most cases of growth hormone deficiency (GHD) in pediatric patients are idiopathic, isolated and acquired. All acquired conditions commence with a period during which the diagnosis maybe unapparent. We document here evidence for evolution GHD group adolescent males who tested sufficient on initial GH stimulation test (GST) but deficient upon reevaluation. The rationale repeat GST was ongoing...