- Cell Adhesion Molecules Research
- Viral gastroenteritis research and epidemiology
- Connective tissue disorders research
- RNA and protein synthesis mechanisms
- Collagen: Extraction and Characterization
- Spectroscopy Techniques in Biomedical and Chemical Research
- Molecular Biology Techniques and Applications
- Animal Virus Infections Studies
University of Jyväskylä
2004-2014
Tampere University
2005
In the integrin family, collagen receptors form a structurally and functionally distinct subgroup. Two members of this subgroup, α1β1 α2β1 integrins, are known to bind monomeric type I collagen. However, in tissues monomers organized into large fibrils immediately after they released from cells. Here, we studied fibril recognition by integrins. By an immunoelectron microscopy method showed that α2I domain is able classical D-banded fibrils. according solid phase binding assay, formation...
ABSTRACT In recent decades, Raman spectroscopy has entered the biological and medical fields. It enables nondestructive analysis of structural details at molecular level been used to study viruses their constituents. Here, we echovirus 1 (EV1), a small, nonenveloped human pathogen, in two different uncoating states induced by heat treatments. signals capsid proteins RNA genome were observed from intact virus, intermediate, disrupted virions. Transmission electron microscopy data revealed...