A5046008906- Functional Brain Connectivity Studies
- Advanced Neuroimaging Techniques and Applications
- Neural dynamics and brain function
- Epilepsy research and treatment
- EEG and Brain-Computer Interfaces
- Neuroscience and Neuropharmacology Research
- Advanced MRI Techniques and Applications
- Optical Imaging and Spectroscopy Techniques
- Natural Fiber Reinforced Composites
- Neurological disorders and treatments
- Nanocomposite Films for Food Packaging
- Traumatic Brain Injury and Neurovascular Disturbances
- Advanced Cellulose Research Studies
- Hormonal Regulation and Hypertension
- Vestibular and auditory disorders
University of Electronic Science and Technology of China
2019-2024
Chinese Academy of Medical Sciences & Peking Union Medical College
2023
Abstract An increasing number of studies in patients with generalized tonic–clonic seizures (GTCS) have reported the alteration functional connectivity (FC) many brain networks. However, little is known about underlying temporal variability FC large‐scale networks patients. Recently, dynamic could provide novel insight into physiological mechanisms brain. Here, we recruited 63 GTCS and 65 age‐ sex‐matched healthy controls. Dynamic approaches were used to evaluate alterations at region‐...
Abstract The aberrant thalamocortical pathways of epilepsy have been detected recently, while its underlying effects on are still not well understood. Exploring pathoglytic changes in two important pathways, that is, the basal ganglia (BG)‐thalamocortical and cerebellum‐thalamocortical people with idiopathic generalized (IGE), could deepen our understanding pathological mechanism this disease. These were reconstructed investigated study by combining diffusion functional MRI. Both showed...
Schizophrenia is accompanied by aberrant interactions of intrinsic brain networks. However, the modulatory effect electroencephalography (EEG) rhythms on functional connectivity (FC) in schizophrenia remains unclear. This study aims to provide new insight into network communication integrating FC and EEG rhythm information. After collecting simultaneous resting-state EEG-functional magnetic resonance imaging data, modulations was explored using what we term "dynamic information." We also...
The present study aims to investigate intrinsic abnormalities of the brain and effect antiepileptic treatment on activity in Benign childhood epilepsy with centrotemporal spikes (BECTS). Twenty-six drug-naïve patients(DNP) 22 drug-receiving patients (DRP) BECTS were collected this study. static amplitude low-frequency fluctuation (sALFF) dynamic ALFF(dALFF) was applied resting-state fMRI data. Functional connectivity (FC) analysis further performed for affected regions identified by...
The dynamic profile of brain function has received much attention in recent years and is also a focus the study epilepsy. present aims to integrate dynamics temporal spatial characteristics provide comprehensive novel understanding epileptic dynamics. Resting state fMRI data were collected from eighty-three patients with idiopathic generalized epilepsy (IGE) 87 healthy controls (HC). Specifically, we explored variation functional connectivity density (tvFCD svFCD) whole brain. Using...
Abstract The interaction between cerebellum and cerebrum participates widely in function from motor processing to high‐level cognitive affective processing. Because of the symptom, idiopathic generalized epilepsy (IGE) patients with tonic–clonic seizure have been recognized associate abnormalities, but functional cerebello–cerebral circuit is still poorly understood. Resting‐state magnetic resonance imaging data were collected for 101 IGE 106 healthy controls. voxel‐based connectivity (FC)...
Idiopathic generalized epilepsy (IGE) is characterized by cryptogenic etiology and the striatum cerebellum are recognized as modulators of epileptic network. We collected simultaneous electroencephalogram functional magnetic resonance imaging data from 145 patients with IGE, 34 whom recorded interictal discharges (IEDs) during scanning. In states without IEDs, hierarchical connectivity was performed to search core cortical regions which might be potentially modulated cerebellum. Node-node...
Abstract Aims Motor abnormalities have been identified as one common symptom in patients with generalized tonic–clonic seizures (GTCS) inspiring us to explore the disease a motor execution condition, which might provide novel insight into pathomechanism. Methods Resting‐state and motor‐task fMRI data were collected from 50 GTCS, including 18 newly diagnosed without antiepileptic drugs (ND_GTCS) 32 receiving (AEDs_GTCS). activation its association head motion cerebral gradients assessed....
The cerebral functional reorganization and declined cognitive function of aging might associate with altered vascular features. Here, we explored the hierarchical network 2 conditions (task-free naturalistic stimuli) in older adults its relationship features (systemic microvascular perfusion features, measured by magnetic resonance imaging) behavior. Using gradient analysis, found that compressive resting-state mainly located on primary sensory-motor system transmodal regions aging, further...
To investigate potential functional and structural large-scale network disturbances in untreated patients with generalized tonic-clonic seizures (GTCS) the effects of antiseizure drugs.In this study, 41 GTCS, comprising 21 20 who received medications (ASMs), 29 healthy controls were recruited to construct brain networks based on resting-state magnetic resonance imaging diffusion tensor imaging. Structural connectivity network-level weighted correlation probability (NWCP) further investigated...
Abstract Objective: The present study aims to investigate the potential disturbance of functional and structural large-scale networks in drug-naive patients with generalized tonic-clonic seizures (GTCS) effects drugs-receiving. Methods: In this study, 41 GTCS, including 21 20 antiepileptic drugs (AEDs), 29 healthy controls were recruited construct brain based on resting-state magnetic resonance imaging (fMRI) diffusion tensor image (DTI). connectivity coupling between structure function...