Background . This study was carried out to establish the prevalence of cardiovascular risks such as hypertension, obesity, and diabetes in Eastern Nepal. also establishes metabolic syndrome (MS) its relationships these risk factors lifestyle. Methods 14,425 subjects aged 20–100 (mean 41.4 ± 15.1) were screened with a physical examination blood tests. Both International Diabetic Federation (IDF) National Cholesterol Education Programme’s (NCEP) definitions for MS used compared. Results 34%...

Nepal cannot afford renal replacement therapy for End Stage Renal Disease due to lack of resources. Early diagnosis Chronic Kidney and its risk factors may reduce the need therapy.A community-based screening on, 3218 people ≥20 years were assessed by door-to-door survey in Dharan, Nepal. Health status, lifestyle habit, physical examination blood pressure evaluated. Spot urine was examined proteins glucose dipstick. Fasting serum creatinine measured a subset 1000 prevalence...

Baseline stroke knowledge in a targeted population is indispensable to promote the effective education. We report baseline knowledge, attitude, and practice (KAP) of high school students with respect from Nepal.A self-structured questionnaire survey regarding KAP about was conducted 33 schools Bharatpur, Nepal. Descriptive statistics including Chi-square test used, significant variables were subjected binary logistic regression.Among 1360 participants, 71.1% had heard or read stroke; 30.2%...

Stroke is a major global health problem and was the second leading cause of death worldwide in 2020. However, lack public stroke awareness especially low- middle-income countries (LMICs) such as Nepal severely hinders effective provision care. Efficient cost-effective strategies to raise LMICs are still lacking. This study aims (a) explore feasibility social media-based campaign using cost-benefit analysis (b) identify best practices for media education campaigns.We performed over period 6...

Introduction . Epilepsy continues to increase worldwide but, unfortunately, many high school students have inadequate knowledge of and negative beliefs towards the disease. We aimed assess knowledge, beliefs, practices epilepsy among Central Nepal. Materials Methods A cross-sectional study was performed involving 1360 from 33 private schools across Bharatpur, June 2013 July 2013, their (KBP) on using a standardized questionnaire. The differences in mean KBP scores between different sexes,...

<ns4:p><ns4:italic>Background:</ns4:italic> Renal impairment is regularly seen in hospitalized stroke patients, affecting the outcome of as well causing difficulties their management. A prospective cohort study was conducted to assess trend renal function ischemic and haemorrhagic patients. The incidence these subgroups, contributing factors need for replacement impaired patients evaluated.</ns4:p><ns4:p> <ns4:italic>Methods:</ns4:italic> Alternate day testing performed Estimated glomerular...

<ns4:p><ns4:italic>Background:</ns4:italic> Renal impairment is regularly seen in hospitalized stroke patients, affecting the outcome of as well causing difficulties their management. A prospective cohort study was conducted to assess trend renal function ischemic and haemorrhagic patients. The incidence these subgroups, contributing factors need for replacement impaired patients evaluated.</ns4:p><ns4:p> <ns4:italic>Methods:</ns4:italic> Alternate day testing performed Estimated glomerular...

Stroke is the major cause of morbidity and mortality worldwide. The number stroke patients receiving recombinant tissue plasminogen activator (rt-PA), also known as Alteplase, in developing world extremely low. We aim to study feasibility efficacy thrombolysis for 1(st) time our country.In this retrospective (July 2012-August 2015), acute ischemic who were thrombolyzed within 3 h onset included. Their demographic profiles, clinical risk factors, type thrombolytic used, outcomes...

Background: Psychiatric disorders are reported remarkably high among 'people living with HIV/AIDS' (PLWHA).It warrants a study in Nepalese context.Objective: To measure the prevalence of common psychiatric adult PLWHA.Method and Materials: It was hospitalbased cross-sectional study.One hundred consecutive consenting PLWHA attending VCT clinic tertiary care hospital within period (1 year) were enrolled after informed written consent.Pertinent informations recorded Proforma.An intensive...

Vitamin D deficiency has been associated with many neurological illnesses. The status of in Nepalese ischemic stroke patients is still unknown. This study aims to assess the vitamin and its association risk factors acute from Central Nepal.A total 60 were included study. Their clinical profile assessed. Frequency distribution, Pearson χ2test Kruskal-Wallis test performed for statistical analysis using SPSS-IBM 20.The median (IQR) age patient was 65 (53.25, 70.75) years, ranging 18-87 years....

Cerebral venous sinus thrombosis (CVST) is a rare but serious disorder that associated with poor clinical outcome. We report 35-year-old man who had severe headache and diplopia while climbing Mount Everest. His MR venography showed right transverse sigmoid thrombosis. He improved on anticoagulant symptomatic measures. at high altitude discussed.

Abstract Introduction We studied the levels and severity of anxiety caused by COVID-19 amongst frontline health-care workers (HCWs) in a tertiary care neurological hospital Nepal, not assigned to manage cases. Methods A cross-sectional study was conducted on 100 Health Care Workers using 10-point subjective assessment tool, Anxiety Level Index (ALI), Zung Self Rating Score (SAS), assess level regarding COVID-19. Results On ALI 55% HCW were found have marked severe (6-9), however, SAS 44%...

Globally, acute ischaemic stroke is the leading cause of disability. Disease burden higher in low-income and middle-income countries (LMICs) than high-income countries, with LMICs seeing 71% stroke-related deaths.1Feigin VL Forouzanfar MH Krishnamurthi R et al.Global regional during 1990–2010: findings from Global Burden Study 2010.Lancet. 2014; 383: 245-254Summary Full Text PDF PubMed Scopus (2635) Google Scholar Nepal a country per-capita income US$1034.2The World BankGDP per capita...

INTRODUCTION:&#x0D; This study was conducted to explore cardiovascular autonomic neuropathy and its pattern in chronic kidney disease patients.&#x0D; METHODS:&#x0D; Autonomic function using five standard tests examined 20 diabetic patients with CKD, age sex matched without CKD controls. Analysis of difference between the done three groups Chi-square test or Fischer's test.&#x0D; RESULTS:&#x0D; Total (100%) were found have neuropathy. Of these, 2 (10%) had early parasympathetic damage, 8...

Myasthenia gravis is a neuromuscular junction disorder characterised by fluctuating muscle weakness, improved using anti-cholinesterase drugs. In addition to the autoimmune aetiology, various factors such as infections, surgery, and drugs are known precipitate condition. We report case of 15-year-old boy with D-penicillamine-induced myasthenia who presented facial diplegia, dysphagia, drooling saliva, 6 years after initiation treatment for Wilson’s disease. Therefore, clinicians should be...

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Access to hemodialysis is limited in Nepal due geographical terrain and centers being mostly major city. Therefore, continuous ambulatory peritoneal dialysis likely be a better option Nepal. In 1998, CAPD was initiated without success. High rate of peritonitis cited for failure. Hot tropical climate poor sense hygiene among patients thought responsible the high peritonitis. A new CPD program started 2002 our institute. We reviewed incidence factors predisposing.All chronic renal failure on...

A 27-year-old man presented with diplopia without features of raised intracranial pressure. He had left sixth cranial nerve (CN) palsy. Initial investigations in the form blood tests, cerebrospinal fluid (CSF) opening pressure including CSF analysis and CT head were normal. represented paraparesis after 3 weeks. Examination revealed CN palsy (eye twist) new left-sided twelfth (tongue twist), hence Godtfredsen syndrome was diagnosed. MRI showed vertebral clivus metastases. partial response to...

Objective. Nondiabetic obese individuals have subclinical involvement of peripheral nerves. We report the factors predicting nerve function in overweight and nondiabetic Nepalese individuals. Methodology. In this cross-sectional study, we included 50 adult volunteers without features neuropathy healthy to determine normative conduction data. cases abnormal function, study population was classified on basis number nerves involved, namely, “&lt;2” or “≥2.” Multivariable logistic regression...

Introduction and importance: Ataxia telangiectasia (A-T) is a rare autosomal recessive neurodegenerative disorder with early childhood onset. It’s characterized by ataxia, oculocutaneous telangiectasia, immunodeficiency, lymphoid-origin cancer predisposition due to ATM gene mutations. Case Presentation: We present 19-year-old girl spastic movements since 18 months, leading wheelchair dependence. Ocular dystonic posture, slurred speech were evident. Diagnosis involved elevated...