- Air Quality and Health Impacts
- Energy and Environment Impacts
- Climate Change and Health Impacts
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Global Health Care Issues
- Health disparities and outcomes
- Child Nutrition and Water Access
- Global Public Health Policies and Epidemiology
- Respiratory and Cough-Related Research
- Pediatric health and respiratory diseases
- Asthma and respiratory diseases
- Global Maternal and Child Health
- Air Quality Monitoring and Forecasting
- Energy, Environment, and Transportation Policies
- Cardiovascular Health and Risk Factors
- Occupational and environmental lung diseases
- Birth, Development, and Health
- COVID-19 impact on air quality
- Nutritional Studies and Diet
- Occupational exposure and asthma
- Obesity, Physical Activity, Diet
- Injury Epidemiology and Prevention
- Blood Pressure and Hypertension Studies
- Menopause: Health Impacts and Treatments
- Advanced Battery Technologies Research
Coventry University
2020-2025
McMaster University
2018-2024
Intelligent Health (United Kingdom)
2020-2024
St. Joseph’s Healthcare Hamilton
2021-2024
Nepal Development Research Institute
2021-2024
Impact
2021-2024
University of Oxford
2013-2023
University College London
2021-2023
Institute for Health Metrics and Evaluation
2020-2023
Maulana Azad National Institute of Technology
2023
<h3>Importance</h3> When combusted indoors, solid fuels generate a large amount of pollutants such as fine particulate matter. <h3>Objective</h3> To assess the associations fuel use for cooking and heating with cardiovascular all-cause mortality. <h3>Design, Setting, Participants</h3> This nationwide prospective cohort study recruited participants from 5 rural areas across China between June 2004 July 2008; mortality follow-up was until January 1, 2014. A total 271 217 adults without...
Adherence to a combination of healthy lifestyle factors has been related considerable reduction cardiovascular risk in white populations; however, little is known whether such associations persist nonwhite populations like the Asian population.
The associations between the extent of forced expiratory volume in 1 s (FEV1) impairment and mortality, incident cardiovascular disease, respiratory hospitalisations are unclear, how these might vary across populations is unknown.In this international, community-based cohort study, we prospectively enrolled adults aged 35-70 years who had no intention moving residences for 4 from rural urban communities 17 countries. A portable spirometer was used to assess FEV1. FEV1 values were...
Over half the world's population, mostly from developing countries, use solid fuel for domestic purposes and are exposed to very high concentrations of harmful air pollutants with potential health effects such as respiratory problems, cardiovascular infant mortality ocular problems. The evidence also suggests that, although total percentage people using is decreasing, absolute number currently increasing. Exposure smoke burning increases risk chronic obstructive pulmonary disease (COPD) lung...
BackgroundThe age-specific association between blood pressure and vascular disease has been studied mostly in high-income countries, before the widespread use of brain imaging for diagnosis main stroke types (ischaemic intracerebral haemorrhage). We aimed to investigate this relationship among adults China.Methods512 891 (59% women) aged 30–79 years were recruited into a prospective study from ten areas China June 25, 2004, July 15, 2008. Participants attended assessment centres where they...
Background: Household air pollution (HAP) from solid fuel use for cooking affects 2.5 billion individuals globally and may contribute substantially to disease burden. However, few prospective studies have assessed the impact of HAP on mortality cardiorespiratory disease. Objectives: Our goal was evaluate associations between mortality, cardiovascular (CVD), respiratory in urban rural epidemiology (PURE) study. Methods: We studied 91,350 adults 35–70 y age 467 communities 11 countries...
BackgroundCooking practice has transitioned from use of solid fuels to clean fuels, with addition better ventilation facilities. However, the change in mortality risk associated such a transition remains unclear.MethodsThe China Kadoorie Biobank (CKB) Study enrolled participants (aged 30–79 years) ten areas across China; we chose study five urban where for cooking was prevalent. Participants who reported regular (weekly or more frequently) at baseline were categorised as persistent fuel...
Breastfeeding confers substantial benefits to child health and has also been associated with lower risk of maternal cardiovascular diseases (CVDs) in later life. However, the evidence on effects CVD is still inconsistent, especially East Asians, whom frequency duration breastfeeding significantly differ from those West.In 2004-2008, nationwide China Kadoorie Biobank recruited 0.5 million individuals aged 30 79 years 10 diverse regions across China. During 8 follow-up, 16 671 incident cases...
Household Air Pollution (HAP) from biomass cooking fuels is a major cause of morbidity and mortality in low-income settings worldwide. In Nepal the use open stoves with solid primary method domestic cooking. To assess patterns air pollution we performed continuous measurement carbon monoxide (CO) particulate Matter (PM2.5) 12 fuel households Janakpur, Nepal. We measured kitchen PM2.5 CO concentrations at one-minute intervals for an approximately 48-h period using TSI DustTrak II 8530/SidePak...
Exposure to household air pollution (HAP) from solid fuel combustion affects almost half of the world population. Adverse respiratory outcomes such as infections, impaired lung growth and chronic obstructive pulmonary disease have been linked HAP exposure. Solid smoke is a heterogeneous mixture various gases particulates. Cell culture animal studies with controlled exposure conditions genetic homogeneity provide important insights into mechanisms. Impaired bacterial phagocytosis in exposed...
Abstract Background Existing evidence on long-term ambient air pollution (AAP) exposure and risk of cardio-respiratory diseases in China is mainly mortality, based area average concentrations from fixed-site monitors for individual exposures. Substantial uncertainty persists, therefore, about the shape strength relationship when assessed using more personalised data. We aimed to examine relationships between AAP predicted local levels AAP. Methods A prospective study included 50,407...
This study aimed to assess the effects of biomass smoke exposure on lung function in a Nepalese population, addressing some methodological issues seen previous studies. We carried out cross-sectional adults population exposed and non-exposed Nepal. Questionnaire data were acquired along with direct measures indoor outdoor air quality. Ventilatory (forced expiratory volume 1 s (FEV ), forced vital capacity (FVC) flow at 25–75% FVC) was significantly reduced using across all age groups...
China has high stroke rates despite the population being relatively lean. Uncertainty persists about relevance of adiposity to risk types. We aimed assess associations with incidence types and effect mediation by blood pressure in Chinese men women.The Kadoorie Biobank enrolled 512 891 adults aged 30-79 years from ten areas (five urban five rural) during 2004-08. During a median 9 (IQR 8-10) follow-up, 32 448 strokes (about 90% confirmed neuroimaging) were recorded among 489 301 participants...
Little evidence from large-scale cohort studies exists about the relationship of solid fuel use with hospitalization and mortality major respiratory diseases.To examine associations risks acute chronic diseases.A study 277,838 Chinese never-smokers no prior diseases at baseline. During 9 years follow-up, 19,823 first episodes or deaths diseases, including 10,553 lower disease (CLRD), 4,398 obstructive pulmonary (COPD), 7,324 infection (ALRI), were recorded. Cox regression yielded adjusted...
In China, the burden of chronic obstructive disease (COPD) is high in never-smokers but little known about its causes this group. We analysed data on 287 000 female and 30 male aged 30–79 years from 10 regions who participated China Kadoorie Biobank baseline survey (2004–2008). Prevalence airflow obstruction (AFO) (pre-bronchodilator forced expiratory volume 1 s (FEV )/forced vital capacity (FVC) <0.7 below lower limit normal (LLN)) was estimated, by age region. Cross-sectional...