Sumathy Rangarajan
A5069728608- Nutritional Studies and Diet
- Obesity, Physical Activity, Diet
- Global Public Health Policies and Epidemiology
- Health disparities and outcomes
- Blood Pressure and Hypertension Studies
- Air Quality and Health Impacts
- Cardiovascular Health and Risk Factors
- Sodium Intake and Health
- Acute Ischemic Stroke Management
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Energy and Environment Impacts
- Climate Change and Health Impacts
- Global Health Care Issues
- Diet and metabolism studies
- Consumer Attitudes and Food Labeling
- Nutrition, Genetics, and Disease
- Nutrition and Health in Aging
- Lipoproteins and Cardiovascular Health
- Cardiac Health and Mental Health
- Health Promotion and Cardiovascular Prevention
- Healthcare Systems and Reforms
- Health and Lifestyle Studies
- Suicide and Self-Harm Studies
- Genetic Associations and Epidemiology
- Sleep and related disorders
Population Health Research Institute
2016-2025
Hamilton Health Sciences
2016-2025
McMaster University
2016-2025
University of Waikato
2024
The University of Western Australia
2022-2023
Impact
2023
Hamilton General Hospital
2008-2022
Rush University Medical Center
2022
University of Calgary
2014-2021
Simon Fraser University
2014-2020
South Asians have high rates of acute myocardial infarction (AMI) at younger ages compared with individuals from other countries but the reasons for this are unclear.To evaluate association risk factors AMI in native Asians, especially ages, countries.Standardized case-control study 1732 cases first and 2204 controls matched by age sex 15 medical centers 5 Asian 10,728 12,431 countries. Individuals were recruited to between February 1999 March 2003.Association AMI.The mean (SD) was lower...
More than 80% of deaths from cardiovascular disease are estimated to occur in low-income and middle-income countries, but the reasons unknown.We enrolled 156,424 persons 628 urban rural communities 17 countries (3 high-income, 10 middle-income, 4 countries) assessed their risk using INTERHEART Risk Score, a validated score for quantifying risk-factor burden without use laboratory testing (with higher scores indicating greater burden). Participants were followed incident death mean 4.1...
Coronary heart disease (CHD) is a leading cause of death among men and women globally. Women develop CHD about 10 years later than men, yet the reasons for this are unclear. The purpose report to determine if differences in risk factor distributions exist between across various age categories help explain why acute MI men.We used INTERHEART global case-control study including 27 098 participants from 52 countries, 6787 whom were women. median first was higher (65 vs. 56 years; P < 0.0001)....
The optimal range of sodium intake for cardiovascular health is controversial.We obtained morning fasting urine samples from 101,945 persons in 17 countries and estimated 24-hour potassium excretion (used as a surrogate intake). We examined the association between urinary composite outcome death major events.The mean was 4.93 g per day 2.12 day, respectively. With follow-up 3.7 years, occurred 3317 participants (3.3%). As compared with an 4.00 to 5.99 (reference range), higher (≥ 7.00 day)...
Higher levels of sodium intake are reported to be associated with higher blood pressure. Whether this relationship varies according or potassium and in different populations is unknown.We studied 102,216 adults from 18 countries. Estimates 24-hour excretion were made a single fasting morning urine specimen used as surrogates for intake. We assessed the between electrolyte pressure, measured an automated device.Regression analyses showed increments 2.11 mm Hg systolic pressure 0.78 diastolic...
The association between intake of fruits, vegetables, and legumes with cardiovascular disease deaths has been investigated extensively in Europe, the USA, Japan, China, but little or no data are available from Middle East, South America, Africa, south Asia.We did a prospective cohort study (Prospective Urban Rural Epidemiology [PURE] 135 335 individuals aged 35 to 70 years without 613 communities 18 low-income, middle-income, high-income countries seven geographical regions: North America...
Socioeconomic status is associated with differences in risk factors for cardiovascular disease incidence and outcomes, including mortality. However, it unclear whether the associations between common measures of socioeconomic status-wealth education-differ among high-income, middle-income, low-income countries, and, if so, why these exist. We explored association education household wealth mortality to assess which marker stronger predictor examined any by parallel factor levels or...
Rheumatic heart disease (RHD) accounts for over a million premature deaths annually; however, there is little contemporary information on presentation, complications, and treatment.This prospective registry enrolled 3343 patients (median age 28 years, 66.2% female) presenting with RHD at 25 hospitals in 12 African countries, India, Yemen between January 2010 November 2012. The majority (63.9%) had moderate-to-severe multivalvular complicated by congestive failure (33.4%), pulmonary...
Diet is a major modifiable risk factor for cardiovascular disease, but it varies markedly in different regions of the world. The objectives present study were to assess association between dietary patterns and acute myocardial infarction (AMI) globally.INTERHEART standardized case-control involving participants from 52 countries. analysis included 5761 cases 10 646 control subjects. We identified 3 using analysis: Oriental (high intake tofu soy other sauces), Western fried foods, salty...
To investigate the association of estimated total daily sleep duration and daytime nap with deaths major cardiovascular events.We durations naps based on amount time in bed self-reported napping examined associations between them composite outcome events 116 632 participants from seven regions. After a median follow-up 7.8 years, we recorded 4381 4365 events. It showed both shorter (≤6 h/day) longer (>8 were associated an increased risk when adjusted for age sex. adjustment demographic...
Abstract Background The measurement of handgrip strength (HGS) has prognostic value with respect to all‐cause mortality, cardiovascular mortality and disease, is an important part the evaluation frailty. Published reference ranges for HGS are mostly derived from Caucasian populations in high‐income countries. There a paucity information on normative values non‐Caucasian low‐ or middle‐income objective this study was develop healthy adults broad range ethnicities socioeconomically diverse...
Background: There are few contemporary data on the mortality and morbidity associated with rheumatic heart disease or information their predictors. We report 2-year follow-up of individuals from 14 low- middle-income countries in Africa Asia. Methods: Between January 2010 November 2012, we enrolled 3343 patients 25 centers followed them for 2 years to assess mortality, congestive failure, stroke transient ischemic attack, recurrent acute fever, infective endocarditis. Results: Vital status...
To evaluate the relation between intake of ultra-processed food and risk inflammatory bowel disease (IBD).Prospective cohort study.21 low, middle, high income countries across seven geographical regions (Europe North America, South Africa, Middle East, south Asia, East China).116 087 adults aged 35-70 years with at least one cycle follow-up complete baseline frequency questionnaire (FFQ) data (country specific validated FFQs were used to document dietary intake). Participants followed...