- Streptococcal Infections and Treatments
- Global Public Health Policies and Epidemiology
- Infective Endocarditis Diagnosis and Management
- Eosinophilic Disorders and Syndromes
- Pulmonary Hypertension Research and Treatments
- Global Health and Epidemiology
- Global Maternal and Child Health
- Cardiovascular Issues in Pregnancy
- Blood Pressure and Hypertension Studies
- Health Systems, Economic Evaluations, Quality of Life
- Eosinophilic Esophagitis
- Congenital Heart Disease Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Kawasaki Disease and Coronary Complications
- Global Health and Surgery
- HIV-related health complications and treatments
- Cardiac Structural Anomalies and Repair
- Acute Myocardial Infarction Research
- Health Policy Implementation Science
- Global Health Care Issues
- Antimicrobial Resistance in Staphylococcus
- Cardiovascular Effects of Exercise
- Otolaryngology and Infectious Diseases
- Healthcare Systems and Reforms
- Cardiac tumors and thrombi
Instituto Nacional de Saúde
2016-2025
Eduardo Mondlane University
2016-2025
Brigham and Women's Hospital
2024
Uganda Management Institute
2024
Invictus Medical (United States)
2024
Makerere University
2016-2024
University of Washington
2023
Ministério da Saúde
2016-2023
Maputo Central Hospital
2023
World Heart Federation
2023
Epidemiologic studies of the prevalence rheumatic heart disease have used clinical screening with echocardiographic confirmation suspected cases. We hypothesized that all surveyed children would show a significantly higher disease.Randomly selected schoolchildren from 6 through 17 years age in Cambodia and Mozambique were screened for according to standard criteria.Clinical examination detected was confirmed by echocardiography 8 3677 5 2170 Mozambique; corresponding rates 95% confidence...
Rheumatic heart disease (RHD) accounts for over a million premature deaths annually; however, there is little contemporary information on presentation, complications, and treatment.This prospective registry enrolled 3343 patients (median age 28 years, 66.2% female) presenting with RHD at 25 hospitals in 12 African countries, India, Yemen between January 2010 November 2012. The majority (63.9%) had moderate-to-severe multivalvular complicated by congestive failure (33.4%), pulmonary...
Background: There are few contemporary data on the mortality and morbidity associated with rheumatic heart disease or information their predictors. We report 2-year follow-up of individuals from 14 low- middle-income countries in Africa Asia. Methods: Between January 2010 November 2012, we enrolled 3343 patients 25 centers followed them for 2 years to assess mortality, congestive failure, stroke transient ischemic attack, recurrent acute fever, infective endocarditis. Results: Vital status...
ardiovascular disease (CVD) accounts for ≈18 million deaths annually worldwide, 1 with major disparities between low-and middle-income countries (LMICs) and high-income countries.LMICs contribute a greater share to the global burden of CVDs, these conditions being responsible 80% all cardiovascular worldwide. 1A reason concern is fact that premature correspond around half in developing countries.Between 2008 2017, contributed 81.1% CVD research output accounted 8.1% 8.5% disability-adjusted...
Endomyocardial fibrosis is the most common restrictive cardiomyopathy worldwide. It has no specific treatment and carries a poor prognosis, since patients present with advanced heart failure. On basis of clinical series, regional variations in distribution have been reported within several countries Africa, Asia, South America, but large-scale data are lacking on epidemiologic features early stages disease.We used transthoracic echocardiography to determine prevalence endomyocardial rural...
Background— Early case detection is vital in rheumatic heart disease (RHD) children to minimize the risk of advanced valvular by preventive measures. The currently utilized World Health Organization (WHO) criteria for echocardiographic diagnosis subclinical RHD emphasize presence pathological valve regurgitation but do not include valves with morphological features without regurgitation. We hypothesized that adding diagnostic might have significant consequences terms rates. Methods and...
Acute rheumatic fever (ARF) and heart disease (RHD) remain major causes of failure, stroke death among African women children, despite being preventable imminently treatable.From 21 to 22 February 2015, the Social Cluster Africa Union Commission (AUC) hosted a consultation with RHD experts convened by Pan-African Society Cardiology (PASCAR) in Addis Ababa, Ethiopia, develop 'roadmap' key actions that need be taken governments eliminate ARF eradicate Africa.Seven priority areas for action...
Background The health of populations living in extreme poverty has been a long-standing focus global development efforts, and continues to be priority during the Sustainable Development Goal era. However, there not systematic attempt quantify magnitude causes burden this specific population for almost two decades. We estimated disease rates by cause world’s poorest billion compared these those high-income populations. Methods defined using multidimensional index. used national-level...
Rheumatic heart disease affects more than 40.5 million people worldwide and results in 306,000 deaths annually. Echocardiographic screening detects rheumatic at an early, latent stage. Whether secondary antibiotic prophylaxis is effective preventing progression of unknown.