A5054356412- Global Public Health Policies and Epidemiology
- Blood Pressure and Hypertension Studies
- Pharmaceutical Economics and Policy
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Health Systems, Economic Evaluations, Quality of Life
- HIV-related health complications and treatments
- Sodium Intake and Health
- Pharmaceutical Practices and Patient Outcomes
- Global Health and Epidemiology
- Biomedical Text Mining and Ontologies
- COVID-19 epidemiological studies
- Semantic Web and Ontologies
- Antifungal resistance and susceptibility
- COVID-19 Pandemic Impacts
- Global Maternal and Child Health
- Nutritional Studies and Diet
- Maternal and fetal healthcare
- Cardiovascular Health and Risk Factors
- Maternal and Perinatal Health Interventions
- COVID-19 and Mental Health
- Cardiovascular Health and Disease Prevention
- Pharmacological Effects and Toxicity Studies
- COVID-19 diagnosis using AI
- Chronic Disease Management Strategies
- Health and Well-being Studies
University of Rwanda
2008-2024
Ghent University
2011-2024
Regional Alliance for Sustainable Development
2021-2023
Ghent University Hospital
2009-2022
Institute for Sustainable Development
2022
Rwanda Development Board
2021
Institute of Pharmacology
2012-2017
Agfa-Gevaert (Belgium)
2015
University Teaching Hospital of Butare
2006
In sub-Saharan Africa (SSA), data on hypertension prevalence in terms of urban or rural and sex difference are lacking, heterogeneous contradictory. addition, there no accurate estimates burden.To estimate the age-specific sex-specific arterial SSA adult populations.We searched for population studies, conducted from 1998 through 2008 SSA. We extracted selected studies available prevalences used a logistic regression model to all age/sex/habitat (urban/rural)/country-specific up 2025. On...
The Global Burden of Diseases, Injuries, and Risk Factors Study 2010 confirms ischemic heart disease stroke as the leading cause death that hypertension is main associated risk factor worldwide. How best to respond rising prevalence in resource-deprived settings a topic ongoing public-health debate discussion. In low-income middle-income countries, socioeconomic inequality cultural factors play role both development access care. Europe, barriers poor communication between health systems...
Fungal infections (FIs) are spreading globally causing a significant public health concern. However, its documentation remains sparse in Africa, particularly Rwanda. This literature review, aims to assess the risk and document current gaps evidence policy. It summarizes published data about FIs Rwanda, including ten reports between 1972-and-2022. Blastomyces, Candida, Cryptococcus, Histoplasma, Microsporum, Pneumocystis, Rhinosporidium, Trichophyton caused human infections. These primarily...
Several studies performed before the introduction of highly active antiretroviral therapy (HAART) have shown that HIV-1 infection is an important cause dilated cardiomyopathy. However, factors associated with development HIV-associated cardiomyopathy in developing countries are still debated.To assess prevalence cardiomyopathy, diagnosed by echocardiography, HIV-infected Rwandese patients not receiving HAART and risk its development.A sample 416 african patients, without a previous definite...
In a double-blind randomized controlled trial, Esther Atukunda and colleagues evaluated whether sublingual misoprostol administered to women in labor was non-inferior intramuscular oxytocin preventing postpartum hemorrhage reducing blood loss. Please see later the article for Editors' Summary
Data on blood pressure trends are scarce or unavailable in Sub-Saharan Africa general and especially the Democratic Republic of Congo. This work addresses this gap by analyzing dynamics prevalence control hypertension a cohort Congolese adults South Kivu.Two phases data collection were conducted including baseline at beginning 2012 follow up 2016. The subjects ≥ 18 years old living urban (n = 4413) rural areas 6453). Hypertension was defined as 140/90 mmHg and/or taking antihypertensive...
The objective of this study was to assess the quality antihypertensive drugs and investigate influence tropical storage conditions. Drug content in vitro dissolution tests were performed on 10 test formulations (from Rwanda) 6 reference Belgium or France) after purchase 6-month under long-term (25 ± 2°C 60 5% relative humidity [RH]) accelerated (40 75 RH) testing Twenty percent substandard at time purchase. After months conditions, 7 8 for combined criteria drug dissolution, whereas no...
Objective To investigate compliance of National Essential Medicines Lists (NEMLs) with the WHO List (WHO/EML) in 2007 and to compare prices antihypertensive drugs between 13 sub-Saharan African countries. Methodology Data on NEMLs drug were collected from 65 public private pharmacies (five each per country). Prices compared International Drug Price Indicator Guide (IDPIG). The cost treatment within a country was calculated using defined daily doses (DDD) countries DDD adjusted for purchasing...
Abstract Background Since the outbreak of COVID-19 pandemic in Rwanda, a vast amount SARS-COV-2/COVID-19-related data have been collected including testing and hospital routine care data. Unfortunately, those are fragmented silos with different structures or formats cannot be used to improve understanding disease, monitor its progress, generate evidence guide prevention measures. The objective this project is leverage artificial intelligence (AI) science techniques harmonizing datasets...
Background. The intestinal parasitic infections (IPIs) are globally endemic, and they constitute the greatest cause of illness disease worldwide. Transmission IPIs occurs as a result inadequate sanitation, inaccessibility to potable water, poor living conditions. Objectives. To determine baseline prevalence among children five years below at Webuye Health Demographic Surveillance (HDSS) area in western Kenya. Methods. Cross-sectional survey was used collect data. Direct saline...
This article is part of the Focus Theme METHODs Information in Medicine on "Managing Interoperability and Complexity Health Systems".SALUS project aims at building an interoperability platform a dedicated toolkit to enable secondary use electronic health records (EHR) data for post marketing drug surveillance. An important component this drug-related adverse events (AE) reporting system designed facilitate accelerate process using automatic prepopulation mechanisms.To demonstrate SALUS...
Abstract Background Hypertension remains the major risk factor for cardiovascular diseases (CVDs) worldwide with a prevalence and mortality in low- middle-income countries (LMICs) among highest. The early detection of hypertension factors is crucial pillar CVD prevention. Design method This cross-sectional study included 4284 subjects, mean age 46 ± 16SD, 56.4% females BMI 26.6 3.7 SD. Data were collected through screening campaign rural area Kirehe District, Eastern Rwanda, objective to...
Factual data exploring the relationship between obesity and diabetes mellitus prevalence from rural areas of sub-Saharan Africa remain scattered are unreliable. To address this scarceness, work reports population study describing in general area Katana (South Kivu Democratic Republic Congo). A cohort three thousand, nine hundred, sixty-two (3962) adults (>15 years old) were followed 2012 2015 (or 4105 person-years during observation period), collected using locally adjusted World Health...
Abstract Objectives To compare three methods for evaluating treatment adherence in a 7-day controlled period malaria children Rwanda. Methods Fifty-six (< 5 years) with were recruited at the University Hospital of Butare, Patients treated quinine sulfate, taste-masked, pellets during seven days: days hospital (in-patient) followed by four-day out-patient period. Three to evaluate medication among patients compared: manual pill count returned tablets, patient self-report and electronic...
Abstract Background: Quinine sulphate (QS), like most other antimalarials, is in tablet form designed for adults. In children, treatment based on breaking the tablets to adapt dose child's bodyweight. However, poor breakability owing design or absence of a score line can lead inaccurate dosage. Furthermore, QS very bitter which reduces its acceptability children. taste-masked pellets have been developed offer more flexibility adapting dosage weight. Aims: To evaluate oral bio-availability...
Cardiovascular diseases (CVD) formerly considered as developed countries pandemic, are becoming nowadays increasingly ubiquitous in developing countries, where addition to a steady increase different risk factors, there is substantial inaccessibility health care. However, data about the burden of CVD lacking many sub-Saharan African and their morbimortality characteristics have […]