A5070508959- Childhood Cancer Survivors' Quality of Life
- Acute Lymphoblastic Leukemia research
- Global Cancer Incidence and Screening
- Lymphoma Diagnosis and Treatment
- Viral-associated cancers and disorders
- Cervical Cancer and HPV Research
- Polyomavirus and related diseases
- Renal and related cancers
- Global Health and Surgery
- Advances in Oncology and Radiotherapy
- Economic and Financial Impacts of Cancer
- Neuroblastoma Research and Treatments
- Cytomegalovirus and herpesvirus research
- Sarcoma Diagnosis and Treatment
- Adolescent and Pediatric Healthcare
- Ethics in Clinical Research
- Histiocytic Disorders and Treatments
- Colorectal Cancer Screening and Detection
- Ethics and Legal Issues in Pediatric Healthcare
- Child and Adolescent Health
- Ovarian cancer diagnosis and treatment
- Acute Myeloid Leukemia Research
- Infectious Diseases and Tuberculosis
- Tuberculosis Research and Epidemiology
- Chronic Lymphocytic Leukemia Research
Carol Davila University of Medicine and Pharmacy
2021-2024
University of Global Health Equity
2022-2024
Duke-NUS Medical School
2020-2024
SingHealth
2020-2024
National University of Singapore
2024
University of Pitesti
2023
Bucharest University of Economic Studies
2023
African Organisation for Research and Training in Cancer
2015-2021
SingHealth Duke-NUS Academic Medical Centre
2020-2021
Clinical Emergency Hospital Bucharest
2006-2021
Global inequalities in access to health care are reflected differences cancer survival. The CONCORD programme was designed assess worldwide and trends population-based In this study, we aimed estimate survival globally for several subtypes of childhood leukaemia. Cancer registries participating were asked submit tumour registrations all children aged 0-14 years who diagnosed with leukaemia between Jan 1, 1995, Dec 31, 2009, followed up until 2009. Haematological malignancies defined by...
Background: Very little is known about the regional variation in incidence of childhood malignancies Africa. The aim study was to perform a comprehensive analysis distribution cancer Sub-Saharan Africa and compare results Globocan estimations.
Background The health of populations living in extreme poverty has been a long-standing focus global development efforts, and continues to be priority during the Sustainable Development Goal era. However, there not systematic attempt quantify magnitude causes burden this specific population for almost two decades. We estimated disease rates by cause world’s poorest billion compared these those high-income populations. Methods defined using multidimensional index. used national-level...
Sexually transmitted infections (STIs) remain an important public health problem with approximately half a billion new cases annually among persons aged 15–49 years. Epidemiological data on STIs women of reproductive age in Swaziland are limited. The availability epidemiological and associated risk factors this population is essential for the development successful prevention, diagnosis management strategies country. study aimed to determine prevalence STIs. A total 655 years were...
Although a few studies have investigated delays in diagnosis and treatment among children adolescents with cancer, this has never been subject of study South Africa. Early is fundamental as it allows timely prevents unnecessary complications.Combined prospective retrospective 194 cancer at Tygerberg Hospital, Cape Town, diagnosed between 2000 2009: 126 patients were included through review the medical charts 68 interviews parents.The median total delay was 34 days (2-1,826). The patient 5...
The “angiogenesis switch”—defined as the active process by which solid tumors develop their own circulation—plays an important role in both tumoral growth and propagation. As malignant tumor grows reaches a critical size, metabolic needs function of ever-increasing distance to nearest emergent blood vessel, can no longer be covered microenvironment peritumoral tissue. Although relatively discrete process, “angiogenic switch” acts limiting stage development present from avascular hyperplasia...
In 2008 the South African Children's Cancer Study Group decided to review epidemiology, management, and chemotherapy response of HIV-positive children with malignancy.This is a retrospective analysis data collected from records diagnosed malignancy at 7 university-based pediatric oncology units serving 8 9 provinces in Africa.Two hundred eighty-eight were 289 malignancies between 1995 2009. Age diagnosis ranged 17 days 18.64 years; median 5.79 years. Of 220 HIV-associated malignancies, there...
Cancers occurring in children Africa are often underdiagnosed, or at best diagnosed late. As a result, survival is poor, even for cancers considered 'curable'. With limited population-level data, understanding the actual burden and from childhood difficult. In this study, we aimed providing estimates most common types of affecting aged 0-14 years, three population-based Eastern African registries; Harare, Zimbabwe (Kaposi sarcoma, Wilms tumour (WT), non-Hodgkin lymphoma (NHL),...
Background: Little is known on the risk of cancer in HIV-positive children sub-Saharan Africa. We examined incidence and factors AIDS-defining other cancers pediatric antiretroviral therapy (ART) programs South Methods: linked records 5 ART Johannesburg Cape Town to those oncology units, based name surname, date birth, folder civil identification numbers. calculated rates obtained hazard ratios (HR) with 95% confidence intervals (CI) from Cox regression models including ART, sex, age degree...
Blindness is an uncommon but devastating complication of tuberculosis meningitis. The main causes are chronically raised intracranial pressure (hydrocephalus and/or tuberculomas) or direct involvement the optic chiasm nerves by basal arachnoiditis (inflammation compression). Antituberculosis therapy combined with corticosteroids and control constitutes mainstay for tuberculous Despite these treatment measures, some patients develop blindness, mainly as a result progressive optochiasmatic...
Abstract Background The incidence of Kaposi's sarcoma (KS) in sub‐Saharan Africa, increased tens times since the onset AIDS epidemic. There is, however, very little literature concerning clinical features this disease, its management and outcome HIV‐positive children Africa. This study describes retrospectively presentation malignancy, outcome, a series children. Patients Methods Seventy with KS HIV infection were admitted consecutively from January 1998 to December 2009 South African...