A5110768316- Global Cancer Incidence and Screening
- Cervical Cancer and HPV Research
- Colorectal Cancer Screening and Detection
- Economic and Financial Impacts of Cancer
- Health Systems, Economic Evaluations, Quality of Life
- Acute Ischemic Stroke Management
- Advances in Oncology and Radiotherapy
- Esophageal Cancer Research and Treatment
- Global Public Health Policies and Epidemiology
- Prostate Cancer Diagnosis and Treatment
- Stroke Rehabilitation and Recovery
- Viral-associated cancers and disorders
- Cancer Risks and Factors
- Ethics in Clinical Research
- BRCA gene mutations in cancer
- Head and Neck Cancer Studies
- Ovarian cancer diagnosis and treatment
- Lymphoma Diagnosis and Treatment
- Pharmaceutical Economics and Policy
- Nutrition, Genetics, and Disease
- Viral Infections and Outbreaks Research
- Childhood Cancer Survivors' Quality of Life
- Hepatitis B Virus Studies
- Bladder and Urothelial Cancer Treatments
- Global Health and Surgery
Kenya Medical Research Institute
2014-2024
African Field Epidemiology Network
2024
John Wiley & Sons (United States)
2016-2024
Liechtenstein Institute
2024
Hudson Institute
2024
Breast cancer is the leading diagnosis and second most common cause of deaths in sub-Saharan Africa (SSA). Yet, there are few population-level survival data from none on differences by stage at diagnosis. Here, we estimate breast within SSA area, country-level human development index (HDI). We obtained a random sample 2,588 incident cases, diagnosed 2008-2015 14 population-based registries 12 countries (Benin, Cote d'Ivoire, Ethiopia, Kenya, Mali, Mauritius, Mozambique, Namibia, Seychelles,...
Cervical cancer is the second most common and leading cause of death in women sub-Saharan Africa (SSA).
Cancer incidence rates are presented for the Nairobi Registry, a population‐based cancer registry (PBCR) covering population of capital city Kenya (3.2 million inhabitants in 2009). Case finding was by active methods, with standard and checks accuracy validity. During period 2004–2008 total 8,982 cases were registered comprising 3,889 men (an age standardized rate (ASR) 161 per 100,000) 5,093 women (ASR 231 1,00,000). Prostate most common 40.6 while breast among 51.7 100,000). Cervical...
Breast cancer (BC) is the leading cause of in sub-Saharan Africa (SSA) with rapidly increasing incidence rates reported Uganda and Zimbabwe. However, magnitude these rising trends premenopausal postmenopausal women unknown most African countries. We used data from Cancer Registry Network on incident breast cancers 11 population-based registries 10 countries representing each four SSA regions. explored changes among before after age 50 by calendar period and, where possible, generational...
Abstract Cervical cancer is the leading cause of death in African women. We sought to estimate population‐based survival and evaluate excess hazards for mortality women with cervical cancer, examining effects country‐level Human Development Index (HDI), age stage at diagnosis. selected a random sample 2760 incident cases, diagnosed 2005 2015 from 13 registries 11 countries (Benin, Cote d'Ivoire, Ethiopia, Kenya, Mauritius, Mozambique, Namibia, Seychelles, South Africa, Uganda Zimbabwe)...
Abstract Background: Prostate cancer is the leading in men sub-Saharan Africa (SSA) regarding incidence and mortality. Published data from a few registries SSA suggest that rates are still rising, but there little comprehensive information on time trends of prostate incidence. Methods: We analyzed registry 13,170 incident cases aged 40 years or above, 12 population-based 11 countries, with at least 10-year span comparable data. Results: observed an increase cumulative risks (CR)...
The Cancer Survival in Africa, Asia, and South America project (SURVCAN-3) of the International Agency for Research on aims to fill gaps availability population-level cancer survival estimates from countries these regions. Here, we analysed 18 cancers using data member registries African Registry Network across 11 sub-Saharan Africa.
Cancers occurring in children Africa are often underdiagnosed, or at best diagnosed late. As a result, survival is poor, even for cancers considered 'curable'. With limited population-level data, understanding the actual burden and from childhood difficult. In this study, we aimed providing estimates most common types of affecting aged 0-14 years, three population-based Eastern African registries; Harare, Zimbabwe (Kaposi sarcoma, Wilms tumour (WT), non-Hodgkin lymphoma (NHL),...
Abstract Objectives To estimate observed and relative survival of prostate cancer patients in sub-Saharan Africa (SSA) to examine the influence age, stage at diagnosis Human Development Index (HDI). Patients methods In this comparative registry study, we selected a random sample 1752 incident cases malign prostatic neoplasm from 12 population-based registries 10 SSA countries, registered between 2005 2015. We analyzed data using Kaplan-Meier Ederer II obtain outcome estimates flexible...
Abstract Background Early detection and prompt access to quality treatment palliative care are critical for good breast cancer outcomes. Interventions require understanding of identified barriers facilitators care. A hermeneutic phenomenological approach, whose purpose is describe feelings lived experiences participants, can expand the existing scope in accessing Kenya. Methods This qualitative research applying focus groups a approach identify from knowledge, perceptions, women with without...
<b><i>Background:</i></b> Despite the increasing global burden of stroke, there are limited data on stroke from Kenya to guide in decision-making. Stroke occurrence sub-Saharan Africa has been associated with poor health outcomes. This study sought establish incidence density and mortality Kenya’s leading public tertiary hospitals for purposes informing clinical practice policy. <b><i>Methods:</i></b> is a prospective conducted at referral...
Abstract Background Cervical cancer (CC) is the most common female in many countries of sub-Saharan Africa (SSA). We assessed treatment guideline adherence and its association with overall survival (OS). Methods Our observational study covered nine population-based registries eight countries: Benin, Ethiopia, Ivory Coast, Kenya, Mali, Mozambique, Uganda, Zimbabwe. Random samples 44–125 patients diagnosed from 2010 to 2016 were selected each. Cancer-directed therapy (CDT) was evaluated for...
Although the countries of Sub‐Sharan Africa represent among most rapidly growing and aging populations worldwide, no previous studies have examined cancer patterns in older adults region as a means to inform policies. Using data from Cancer Incidence Five Continents, we describe recent trends incidence rates for major sites aged ≥60 years people 0–59 comparison four selected population‐based registries Kenya (Nairobi), Republic South (Eastern Cape Province), Uganda (Kyadondo country),...
Abstract Ovarian cancer (OC) is one of the commonest cancers women in sub‐Saharan Africa (SSA), although to date no data have been available on time trends incidence better understand disease pattern region. We estimate by histological subtype from 12 population‐based registries 11 countries: Kenya (Nairobi), Mauritius, Seychelles, Uganda (Kampala), Congo (Brazzaville), Zimbabwe (Bulawayo and Harare), Cote d'Ivoire (Abidjan), The Gambia, Mali (Bamako), Nigeria (Ibadan) South (Eastern Cape)....
Background: Breast cancer (BC) is the most common in sub-Saharan Africa (SSA). However, little known about actual therapy received by women with BC and their survival outcome at population level SSA. This study aims to describe cancer-directed patients SSA, compare these results NCCN Harmonized Guidelines for SSA (NCCN Guidelines), evaluate impact on survival. Methods: Random samples of (≥40 per registry), diagnosed from 2009 through 2015, were drawn 11 urban population–based registries 10...
Cardiovascular diseases are the second leading cause of morbidity and mortality in Kenya. However, there is limited clinic-epidemiological data on stroke to inform decision making. This study sought establish distribution patterns characteristics patients seeking care at Kenyatta National Hospital (KNH) Moi Teaching Referral (MTRH), with ultimate aim establishing first national registry Kenya.This was a prospective multicentre cohort among patients. The used modified World Health...
We investigated the ethnic differences in risk of several cancers population Nairobi, Kenya, using data from Nairobi Cancer Registry. The registry records variable “Tribe” for each case, a categorisation that includes, as well 22 tribal groups, categories Kenyans European and Asian origin, non‐Kenyan Africans. Tribes included final analysis were Kikuyu, Kamba, Kisii, Kalenjin, Luo, Luhya, Somalis, Asians, non‐Kenyans, Caucasians, Other tribes unknown. largest group was taken reference...
In response to a growing cancer burden and need for improved coordination among stakeholders in Kenya, the US National Cancer Institute Kenya Ministry of Health collaboratively hosted stakeholder meeting 2014 which identified four priority areas (research capacity building, pathology registries, awareness education, health system strengthening) developed corresponding action plans.Surveys were conducted with participants collect input on progress impact meeting.Of 69 eligible participants,...
Abstract Cancer is the third leading cause of death in Kenya. However, there scarce information on nutritional status cancer patients to guide decision making. The present study sought assess risk malnutrition, and factors associated with malnutrition cachexia, among out-patients, aim informing nutrition programmes for management Kenya beyond. This was a facility-based cross-sectional performed at Kenyatta National Hospital Texas Centre Nairobi, assessed using Malnutrition Universal...