A5033409292- Medical and Health Sciences Research
- Medical Practices and Rehabilitation
- Health and Medical Studies
- MRI in cancer diagnosis
- Radiomics and Machine Learning in Medical Imaging
- Nutrition and Health in Aging
- Insurance, Mortality, Demography, Risk Management
- Frailty in Older Adults
- Venous Thromboembolism Diagnosis and Management
- Global Cancer Incidence and Screening
- Head and Neck Cancer Studies
- Criminal Law and Policy
- Digitalization, Law, and Regulation
- Health Systems, Economic Evaluations, Quality of Life
- Meningioma and schwannoma management
- Cervical Cancer and HPV Research
- Clinical practice guidelines implementation
- Head and Neck Surgical Oncology
- Statistical Methods and Inference
- Health disparities and outcomes
- Cancer Diagnosis and Treatment
- Birth, Development, and Health
- Breast Lesions and Carcinomas
- Hepatocellular Carcinoma Treatment and Prognosis
- Colorectal Cancer Screening and Detection
Martin Luther University Halle-Wittenberg
2016-2025
Charité - Universitätsmedizin Berlin
2024
University Hospital in Halle
2012-2024
Institut für Medizinische Biometrie, Informatik und Epidemiologie
2011-2024
University Hospital Magdeburg
2023
LMU Klinikum
2023
Ludwig-Maximilians-Universität München
2023
University Hospital Heidelberg
2020
Center for Clinical Studies
2020
University Hospital Leipzig
2020
The aim of the present study was to evaluate and distinguish between environmental genetic effects for death from coronary heart disease (CHD) as well determine whether importance influences is changing with age.A cohort a follow-up time 36 years.The drawn includes 20 966 twins born in Sweden 1886 1925 where both within pair still lived country 1961.Concordances correlated gamma-frailty model were used assess age-related changes influences.A total number 4007 CHD-deaths (2208 males, 1799...
The purpose of this meta-analysis was to provide clinical evidence regarding relationship between ADC and cellularity in different tumors based on large patient data. Medline library screened for associations cell count up September 2016. Only publications English were extracted. Preferred Reporting Items Systematic Reviews Meta-Analyses statement (PRISMA) used the research. Overall, 39 with 1530 patients included into analysis. following data extracted from literature: authors, year...
Abstract Background: Localization of dural fistulas in the region anterior or lateral skull base may be difficult. For many years, a sodium fluorescein solution 0.5 to 5% (2.5–50 mg) has been administered intrathecally by way lumbar space. However, is not commercially available for this stated purpose either Germany United States. Methods: Retrospectively, 420 applications authors were retrospectively analyzed. Under Freedom Information Act, States Federal Drug Administration and...
// Alexey Surov 1, * , Hans Jonas Meyer and Andreas Wienke 2, 1 Department of Diagnostic Interventional Radiology, University Leipzig, Germany 2 Institute Medical Epidemiology, Biostatistics, Informatics, Martin Luther Halle-Wittenberg, Halle, These authors contributed equally to this work Correspondence to: Surov, email: Alexey.Surov@medizin.uni-leipzig.de Keywords: diffusion weighted imaging, ADC, ki 67 Received: June 23, 2017 Accepted: August 15, Published: 24, ABSTRACT Diffusion imaging...
The purpose of this study was to determine the prevalence, clinical signs and radiological features breast lymphoma.This is a retrospective review 36 patients with lymphoma (22 primary 14 secondary). 35 were female 1 male; their median age 65 years (range 24-88 years). In all patients, diagnosis confirmed histopathologically.The prevalence 1.6% identified cases non-Hodgkin 0.5% cancer. B-cell found in 94% T-cell 6%. 96 lesions (2.7 per patient). mean size 15.8 ± 8.3 mm. number intramammary...
To analyze diffusion-weighted imaging (DWI) findings of meningiomas and to compare them with tumor grade, cell count, proliferation index test a possibility use apparent diffusion coefficient (ADC) differentiate benign from atypical/malignant tumors.Forty-nine were analyzed. DWI was done using multislice single-shot echo-planar sequence. A polygonal region interest drawn on ADC maps around the margin lesion. In all lesions, minimal values (ADCmin) mean (ADCmean) estimated. Normalized (NADC)...
To identify potential risk factors for the development of jaw osteoradionecrosis (ORN) after 3D-conformal radiotherapy (3D-CRT) and intensity-modulated (IMRT) among patients with newly diagnosed head neck cancer.
Abstract Objectives As periodontal bacteria might be involved in the aetiology of rheumatic diseases, we analysed synovial fluid obtained from patients with rheumatoid arthritis ( RA ) and controls for presence DNA A ggregatibacter actinomycetemcomitans, P orphyromonas gingivalis, revotella intermedia, T annerella forsythia, reponema denticola . Methods In all, 42 suffering (mean age 53.8 ± 16.7 years, 40.4% females) 114 no diseases 56.1 15.2 52.4% were included. was isolated by QiaAmp kit...
The purpose of this part the meta-analysis was to summarize data regarding associations between minimum apparent diffusion coefficient (ADCmin) and KI 67 in different tumors. MEDLINE library screened for ADCmin tumors up April 2017. Overall, 23 studies with 944 patients were identified. Associations ADC analyzed by Spearman's correlation coefficient. pooled all included ρ = -0.47. In detail, coefficients separate as follows: cerebral lymphoma: -0.61 (95% CI [-0.82; -0.41]); cervical cancer:...
Abstract Objectives To investigate associations between apparent diffusion coefficient (ADC) and cell count, Ki 67, tumor-stroma ratio (TSR), tumoral lymphocytes in different hepatic malignancies. Methods We identified 149 cases with performed liver biopsies: hepatocellular cancer (HCC, n = 53), intrahepatic cholangiocarcinoma (iCC, 29), metastases of colorectal (CRC, 24), breast (BC, 28), pancreatic (PC, 15). MRI was on a 1.5-T scanner an axial echo-planar sequence. done before biopsy....
The study aim was to compare the prevalence of asthma, rhinitis and eczema in children living Munster, western Germany, Greifswald, eastern investigate associations several characteristics exposures with atopic disease symptoms. In 1994 1995, questionnaire information gathered on 5-8 yr old (n=3,741 Munster n=2,857 Greifswald) 12-15 olds (n=4,003 n= 3,153, respectively) using phase I protocol International Study Asthma Allergies Childhood (ISAAC). 12 month period prevalences reported...
Numerous studies have analyzed associations between apparent diffusion coefficient (ADC) and histopathological features such as Ki-67 proliferation index in breast cancer (BC), with mixed results. The purpose of this study was to perform a multicenter analysis determine relationships ADC expression tumor grade BC.For study, data from six centers were acquired. sample comprises 870 patients (all female; mean age, 52.6 ± 10.8 years). In every case, magnetic resonance imaging diffusion-weighted...
Abstract Background Early diagnosis is a key determinant of breast cancer prognosis and survival. More than half cases are diagnosed at an advanced stage in Ethiopia, the barriers to early this country not well understood. We aimed identify perceived from perspective patients health care providers south southwestern Ethiopia. Methods A qualitative study was conducted March April 2018 using in-depth interviews six public hospitals located urban rural areas All participants provided verbal...
Risk factors for oropharyngeal dysphagia (OD) in elderly patients are mainly central nervous system (CNS) and structural organic diseases or presbyphagia. We analysed the OD prevalence association of with multimorbidity polypharmacy using real-life data to complete this spectrum, a focus on further iatrogenic risk. This was cross-sectional retrospective study based random sample 200 admitted geriatric hospital. Data analysis included diagnoses, detailed list drugs, an intense clinical...
Abstract Background Patients with cirrhosis and ascites (and portal hypertension) are at risk of developing acute kidney injury (AKI). Although many etiologies exist, hepatorenal AKI (HRS-AKI) remains a frequent difficult-to-treat cause, very high mortality when left untreated. The standard care is the use terlipressin albumin. This can lead to reversal AKI, which associated survival. Nevertheless, only approximately half patients achieve this even after for new episodes HRS-AKI. TIPS...