Daniel Thomas Ginat

ORCID: 0000-0003-3301-4364
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About
Contact & Profiles
Research Areas
  • Head and Neck Surgical Oncology
  • Radiomics and Machine Learning in Medical Imaging
  • Head and Neck Cancer Studies
  • Salivary Gland Tumors Diagnosis and Treatment
  • Glioma Diagnosis and Treatment
  • Meningioma and schwannoma management
  • Nasal Surgery and Airway Studies
  • Advanced X-ray and CT Imaging
  • Sinusitis and nasal conditions
  • Tumors and Oncological Cases
  • Intracranial Aneurysms: Treatment and Complications
  • Pituitary Gland Disorders and Treatments
  • Facial Rejuvenation and Surgery Techniques
  • Head and Neck Anomalies
  • Ear and Head Tumors
  • Ear Surgery and Otitis Media
  • Oral and Maxillofacial Pathology
  • Pharmacological Effects and Toxicity Studies
  • Radiation Dose and Imaging
  • Neurological Complications and Syndromes
  • Bone Tumor Diagnosis and Treatments
  • Medical Imaging Techniques and Applications
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Venous Thromboembolism Diagnosis and Management
  • Facial Trauma and Fracture Management

University of Chicago
2016-2025

University of Illinois Chicago
2017-2022

University of Chicago Medical Center
2013-2022

University of Illinois Hospital & Health Sciences System
2022

Radiation Oncology Associates
2022

University of Maryland, Baltimore
2022

Detroit Medical Center
2020

Neuroscience Institute
2016

Creative Commons
2016

University Radiology
2016

BackgroundPatients with HPV+ oropharyngeal squamous cell carcinoma were assigned to dose and volume de-escalated radiotherapy (RT) or chemoradiotherapy (CRT) based on response induction chemotherapy in an effort limit treatment-related toxicity while preserving efficacy.Patients methodsPatients classified as low-risk (≤T3, ≤N2B, ≤10 pack-year history) high-risk (T4 ≥N2C >10 PYH). After three cycles of carboplatin/nab-paclitaxel, was assessed using Response Evaluation Criteria Solid Tumors...

10.1093/annonc/mdy522 article EN publisher-specific-oa Annals of Oncology 2018-11-26

Importance Immune checkpoint inhibitors improve survival in recurrent and/or metastatic head and neck cancer, yet their role curative human papillomavirus−positive oropharyngeal cancer (HPV + OPC) remains undefined. Neoadjuvant nivolumab chemotherapy followed by response-adaptive treatment HPV OPC may increase efficacy while reducing toxicity. Objective To determine the deep response rate tolerability of addition neoadjuvant to response-adapted locoregional therapy (LRT) patients with OPC....

10.1001/jamaoncol.2024.1530 article EN JAMA Oncology 2024-06-06

Various substances, including methemoglobin, melanin, lipid, protein, calcium, iron, copper, and manganese, are responsible for the intrinsically high signal intensity observed in intracranial lesions at T1-weighted magnetic resonance (MR) imaging. Many of these substances have physical properties that lead to other specific imaging features as well. For example, lipid-containing frequently produce chemical shift artifact, some melanin-containing exhibit a combination on images low...

10.1148/rg.322105761 article EN Radiographics 2012-03-01

Elastography is a technique that maps relative tissue stiffness. Ultrasonographic (US) elastography (sonoelastography) novel modality the subject of active research for clinical applications, primarily breast and prostate lesion imaging. Breast tumors generally have biomechanical properties different from those normal tissues: Tumors are usually stiffer. This phenomenon responsible contrast on elastograms. For gland breast, main image acquisition techniques vibration sonoelastography...

10.1148/rg.297095058 article EN Radiographics 2009-11-01

The objective of our study was to determine the utility diffusion-weighted imaging (DWI) and cell density for differentiating benign from malignant skull lesions.A retrospective review performed. Minimum apparent diffusion coefficient (ADC) values were measured normalized white matter, which we refer as "normalized ADC," in 24 lesions (12 12 benign) 18 patients. In addition, densities 15 cases correlated with ADC values.The average minimum tumors 0.70 × 10(-3) mm(2)/s versus 1.11 (p =...

10.2214/ajr.11.7424 article EN American Journal of Roentgenology 2012-05-22

Neurosarcoidosis is an uncommon condition with protean manifestations. Magnetic resonance imaging (MRI) often used in the diagnostic evaluation and follow-up of patients neurosarcoidosis. Therefore, familiarity variety MRI appearances important. In this pictorial essay, range possible patterns involvement neurosarcoidosis are depicted discussed. These include intracranial spine leptomeningeal involvement, cortical cerebral white matter lesions, corpus callosum sellar suprasellar...

10.4103/2156-7514.76693 article EN PubMed 2011-01-01

Background. Salivary gland secretory carcinoma is usually a low-grade neoplasm. However, high-grade transformation can occur and has important implications for clinical outcome. Methods. A patient presented with an enlarging buccal mass. Magnetic resonance imaging (MRI) showed tumor biphasic appearance along the right parotid duct. Local excision histopathologic examination confirmed diagnosis of transformation. ETV6-NTRK3 translocation loss CDKN2A/B were identified. Results. The...

10.1177/1066896917709350 article EN International Journal of Surgical Pathology 2017-05-12

Oropharyngeal squamous cell carcinoma (OPSCC) is a type of head and neck (HNSCC). The incidence distant metastasis from HNSCC approximately 10-15%. most frequent organs include the bone, liver, lungs, occurrence to colon very rare. To date, treatment recommendation for these patients, especially local treatment, unclear. This case reports real rare metastatic location OPSCC, thus expanding our knowledge OPSCC. At same time, it suggests that has potential value in patients with HNSCC, those...

10.21037/tcr-24-1744 article EN Translational Cancer Research 2025-01-13

Immune checkpoint inhibitors have shown promise in improving the survival rates for recurrent and/or metastatic head and neck cancers. However, their impact on curative outcomes cancers remains undefined, especially those with locoregionally advanced oropharyngeal carcinoma (LAOPC), a subtype of head-and-neck malignancy closely associated human papillomavirus infection. This study aimed to clarify efficacy safety addition programmed cell death protein 1 (PD-1) inhibitor into preoperative...

10.21037/tcr-2025-202 article EN Translational Cancer Research 2025-02-01

Background In patients who have undergone ischemic stroke therapy, retained iodine-based contrast can resemble acute intracranial hemorrhage (ICH) on standard computed tomography (CT). The purpose of this study is to determine the accuracy commercially available artificial intelligence software for differentiating from in such cases. Methods A total 45 CT scans analyzed by Aidoc that also included dual-energy iodine subtraction maps dual energy 23 unique (12 male, 11 female, age range 30–99...

10.3389/fneur.2025.1458142 article EN cc-by Frontiers in Neurology 2025-03-04

Neoadjuvant immunotherapy in human papillomavirus (HPV)-negative locoregionally advanced (LA) head and neck squamous cell carcinoma (HNSCC) appears promising, yet its role nonsurgical treatment for cancer remains undefined. nivolumab plus chemotherapy followed by response-stratified de-escalated chemoradiation therapy (CRT) HPV-negative LA stage IVa/b HNSCC may improve efficacy while reducing treatment-related toxic effects. To determine the deep response rate tolerability of neoadjuvant CRT...

10.1001/jamaoncol.2025.0081 article EN JAMA Oncology 2025-03-06

Obstructive sleep apnea (OSA) can result from various causes of partial or complete obstruction the upper airway. CT is amenable to quantitative analysis airway and surrounding structures. also useful for identifying abnormalities that could be attributed patient’s symptoms relevant surgical planning. There are procedures performed OSA encountered on CT. The anatomic measurements, imaging features pathologies affect airway, postoperative reviewed in this article.

10.1097/rct.0000000000001748 article EN Journal of Computer Assisted Tomography 2025-03-20
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