A5044171040- Head and Neck Cancer Studies
- Cardiac, Anesthesia and Surgical Outcomes
- Surgical Simulation and Training
- Patient-Provider Communication in Healthcare
- Tracheal and airway disorders
- Head and Neck Surgical Oncology
- Hospital Admissions and Outcomes
- Reconstructive Surgery and Microvascular Techniques
- Cancer-related molecular mechanisms research
- Digital Imaging in Medicine
- Salivary Gland Tumors Diagnosis and Treatment
- Medical Malpractice and Liability Issues
- Cervical Cancer and HPV Research
- Dysphagia Assessment and Management
- Healthcare cost, quality, practices
- Lung Cancer Research Studies
- Voice and Speech Disorders
- Innovations in Medical Education
- Head and Neck Anomalies
- Ethics in medical practice
- Meningioma and schwannoma management
- Patient Satisfaction in Healthcare
- Oral Health Pathology and Treatment
- Ear and Head Tumors
- Plant Disease Resistance and Genetics
Vanderbilt University Medical Center
2016-2025
Ethics and Public Policy Center
2020-2024
Vanderbilt University
2011-2023
Nashville Oncology Associates
2011-2023
Institute for Development and Economic Analysis
2023
St. Michael's Hospital
2021
Vanderbilt-Ingram Cancer Center
2021
Vanderbilt Health
2021
Triological Society
2020
University of Chicago
2009-2018
Abstract Purpose: The genetic differences between human papilloma virus (HPV)–positive and –negative head neck squamous cell carcinomas (HNSCC) remain largely unknown. To identify differential biology novel therapeutic targets for both entities, we determined mutations copy-number aberrations in a large cohort of locoregionally advanced HNSCC. Experimental Design: We performed massively parallel sequencing 617 cancer-associated genes 120 matched tumor/normal samples (42.5% HPV-positive)....
<h3>Importance</h3> Patients with frailty have higher risk for postoperative mortality and complications; however, most research has focused on small groups of high-risk procedures. The associations among frailty, operative stress, are poorly understood. <h3>Objective</h3> To assess the association between at varying levels stress as measured by Operative Stress Score, a novel measure created this study. <h3>Design, Setting, Participants</h3> This retrospective cohort study included veterans...
Surgical treatment comparisons in rare diseases are difficult secondary to the geographic distribution of patients. Fortunately, emerging technologies offer promise reduce these barriers for research.To prospectively compare outcomes 3 most common surgical approaches idiopathic subglottic stenosis (iSGS), a airway disease.In this international, prospective, 3-year multicenter cohort study, 810 patients with untreated, newly diagnosed, or previously treated iSGS were enrolled after undergoing...
To evaluate the outcomes, growth rate, and symptoms of nonoperated cervical paragangliomas.Retrospective review clinical radiologic records images.Tertiary academic medical center.We studied all patients presenting with paragangliomas between 1993 2010 who were observed rather than operated on.Growth tumors need for surgical removal.Forty-three 47 identified. Mean patient age was 56 years (age range, 17-86 years). Thirty asymptomatic (70%) (22 diagnosed by imaging other reasons 8 workup a...
Abstract The use of digital technology is increasing rapidly across surgical specialities, yet there no consensus for the term ‘digital surgery’. This critical as health technologies present technical, governance, and legal challenges which are unique to surgeon patient. We aim define surgery ethical issues surrounding its clinical application, identify barriers research goals future practice. 38 international experts, fields surgery, AI, industry, law, ethics policy, participated in a...
Abstract The North American Airway Collaborative (NoAAC) previously published a 3‐year multi‐institutional prospective cohort study showing variation in treatment effectiveness between 3 primary surgical techniques for idiopathic subglottic stenosis (iSGS). In this report, we update these findings to include 5 years of data evaluating effectiveness. Patients the NoAAC were re‐enrolled 2 additional and followed using prespecified protocol. Consistent with prior data, observation 487 iSGS...
<h3>Objective</h3> To review the incidence of aspiration after chemoradiation therapy in patients with head and neck cancer (HNC). <h3>Design</h3> Retrospective review. <h3>Setting</h3> Academic institution. <h3>Patients</h3> One hundred thirty advanced HNC underwent at our institution between 1998 2002 as part a larger, multi-institutional, prospective study induction chemotherapy followed by therapy; 118 (91%) for whom oropharyngeal motility (OPM) data were available are discussed this...
Summary: Our case report describes a young male mechanic who was hit in his face by spring while repairing car, resulting traumatic injury to the frontal sinus, with fractures of both anterior and posterior tables dural defect cerebrospinal fluid leak. Current guidelines recommend that comminuted and/or displaced table sinus defects should be either cranialized or obliterated. In this patient, instead cranializing obliterating we managed preserve anatomy its outflow tract using combined open...
Objective To examine the effect of giving antibiotics on day surgery (DOS) vs DOS and first postoperative (DOS+1) for prophylaxis against surgical site infection (SSI) in clean‐contaminated head neck (CCHNS). Study Design Retrospective multi‐institution analysis using University HealthSystem Consortium data. Methods A multivariate logistic regression model 8836 discharge records from patients undergoing CCHNS was used to determine odds SSI antibiotic agent/duration combinations. Setting...
Objective: Operating rooms (OR) generate a large portion of hospital revenue and waste. Consequently, improving efficiency reducing waste is high priority. Our objective was to quantify associated with opened but unused instruments from trays compare this the cost individually wrapping instruments.Methods: Data collected June November 2013 in 550-bed United States. We recorded instrument usage two commonly-used for ten cases each. The time decontaminate reassemble peel packs measured,...
Abstract Background Numerous challenges exist in determining surgical margin status. Communication between surgeons and pathologists is crucial for specimen orientation accurate assessment. Methods A prospective study to determine feasibility of incorporating three‐dimensional (3D) scanning into pathology workflow was performed. structured‐light 3D scanner captured the photorealistic surface topography fresh specimens. Computer‐aided design (CAD) software used document sites sampling...
ABSTRACT Background Time from surgery to initiation of postoperative radiation therapy (PORT) less than 6 weeks was recently instituted as the first quality metric within head and neck cancer care. Methods We performed a retrospective single institution cohort study investigate predictors PORT delay impact on survival. Results rate 73.2%, with median time treatment 51 days. Outside facility independently associated increased likelihood (OR 1.94, 95% CI 1.03–3.74, p = 0.043). location did not...
The treatment summary (TS) remains underused in head and neck cancer (HNC). We determine if receiving a personalized TS following definitive HNC improves patient recall of details. A history questionnaire was administered to assess accuracy reporting diagnosis treatment-related details at baseline (pre-TS) 1-month follow-up (post-TS). Statistical significance changes assessed using McNemar's chi squared test. One hundred participants were enrolled between January December 2022. Ninety-one...
Abstract Objective Determine relationships between pain and mental health disorders (MHDs) in patients undergoing microvascular free flap reconstruction for head neck cancer (HNC). Study Design Retrospective cohort. Setting Tertiary Care Institution the Southeastern United States. Methods Clinical data were manually abstracted from digital records to obtain demographic, MHD, clinical outcomes, HNC who underwent 2017 2023. Univariate multivariable regression analyses performed delineate MHDs...
ABSTRACT Objectives The osteocutaneous radial forearm free flap (OCRFFF) is used for the reconstruction of bony head and neck defects. Being a weight‐bearing bone, precise harvesting radius required to maintain structural integrity, postoperative function, prevent fracture. A cutting guide may allow surgeons be more confident in performing harvest, improve allocation orthopedic specialist resources. Methods custom was developed an iterative process with six one hand surgeon. Following design...
Our website uses cookies to enhance your experience. By continuing use our site, or clicking "Continue," you are agreeing Cookie Policy | Continue JAMA Surgery HomeNew OnlineCurrent IssueFor Authors Podcast Publications Network Open Cardiology Dermatology Health Forum Internal Medicine Neurology Oncology Ophthalmology Otolaryngology–Head & Neck Pediatrics Psychiatry Archives of (1919-1959) JN Learning / CMESubscribeJobsInstitutions LibrariansReprints Permissions Terms Use Privacy...