A5009979899- Tracheal and airway disorders
- Voice and Speech Disorders
- Dysphagia Assessment and Management
- Esophageal and GI Pathology
- Airway Management and Intubation Techniques
- Respiratory and Cough-Related Research
- Gastroesophageal reflux and treatments
- Cerebrovascular and Carotid Artery Diseases
- Head and Neck Cancer Studies
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Interpreting and Communication in Healthcare
- Intracranial Aneurysms: Treatment and Complications
- Botulinum Toxin and Related Neurological Disorders
- Vascular Anomalies and Treatments
- Head and Neck Anomalies
- Ear and Head Tumors
- Otolaryngology and Infectious Diseases
- Trigeminal Neuralgia and Treatments
- Fibroblast Growth Factor Research
- Head and Neck Surgical Oncology
- Salivary Gland Tumors Diagnosis and Treatment
- Facial Nerve Paralysis Treatment and Research
- Neurological disorders and treatments
- IgG4-Related and Inflammatory Diseases
- Digital Imaging in Medicine
Mayo Clinic
2016-2025
WinnMed
2015-2025
Mayo Clinic in Arizona
2015-2024
Mayo Clinic in Florida
2022-2023
Pioneer (United States)
2023
Jacksonville College
2022
University of Minnesota Rochester
2012-2018
Barro Colorado Island
2016
Vanderbilt University
2009
University of Michigan–Ann Arbor
2005
Abstract Objectives/Hypothesis: To define the prevalence of tracheotomy tube complications and evaluate risk factors (RFs) associated with their occurrence. Study Design: Multi‐institution historical cohort. Methods: Data regarding from consecutive surgeries performed across eight participating institutions between January 1, 2008 December 31, 2009 were retrospectively collected. Patient demographics, comorbidities, physician specialty, surgical technique recorded statistically analyzed to...
Idiopathic subglottic stenosis (ISS) is a rare type of airway unclear etiology. Open resection, while effective, remains complex surgery and requires hospital stay. Endoscopic management often preferred but has historically been associated with high recurrence rate. We aimed to analyze our experience, consisting standardized endoscopic approach combined an empiric medical treatment.Retrospective cohort study.All patients ISS managed treatment at institution between 1987 2012 were identified,...
Surgical treatment comparisons in rare diseases are difficult secondary to the geographic distribution of patients. Fortunately, emerging technologies offer promise reduce these barriers for research.To prospectively compare outcomes 3 most common surgical approaches idiopathic subglottic stenosis (iSGS), a airway disease.In this international, prospective, 3-year multicenter cohort study, 810 patients with untreated, newly diagnosed, or previously treated iSGS were enrolled after undergoing...
Objectives/Hypothesis Idiopathic subglottic stenosis (iSGS) is a rare and potentially life‐threatening disease marked by recurrent progressive airway obstruction frequently requiring repeated surgery to stabilize the airway. Unknown etiology low prevalence have limited ability characterize natural history of iSGS resulted in variability surgical management. It uncertain how this variation relates clinical outcomes. Study Design Medical record abstraction. Methods Utilizing an international,...
Objectives/Hypothesis Idiopathic subglottic stenosis (iSGS) is a rare and devastating extrathoracic obstruction involving the lower laryngeal upper tracheal airway. It arises without known antecedent injury or associated disease process. Persistent mucosal inflammation localized fibrotic response are hallmarks of disease. Despite initial clinical description iSGS more than 40 year ago, there have been no substantive investigations into pathogenesis this enigmatic progressive airway...
Objectives/Hypothesis Idiopathic subglottic stenosis (iSGS) is an unexplained obstruction involving the lower laryngeal and upper tracheal airway. Persistent mucosal inflammation a hallmark of disease. Epithelial microbiota dysbiosis found in other chronic inflammatory diseases; however, relationship between composition iSGS unknown. Given critical role for host defense at barriers, we analyzed tissue specimens from patients presence microbial pathogens. Methods Utilizing 30 human iSGS, 20...
Abstract The North American Airway Collaborative (NoAAC) previously published a 3‐year multi‐institutional prospective cohort study showing variation in treatment effectiveness between 3 primary surgical techniques for idiopathic subglottic stenosis (iSGS). In this report, we update these findings to include 5 years of data evaluating effectiveness. Patients the NoAAC were re‐enrolled 2 additional and followed using prespecified protocol. Consistent with prior data, observation 487 iSGS...
Objective(s): To quantify and compare pre-procedure worry versus the experience of pain, gagging, dyspnea during in-office laryngoscopy procedures in patients who did or not receive anxiolytics, to explore patient perception intra-procedure interventions. Methods: Patients undergoing awake laryngology at a quaternary care center were enrolled. The State-Trait Anxiety Inventory (STAI) Y1 Y2 questionnaires administered establish baseline levels state anxiety trait anxiety, respectively....
Idiopathic subglottic stenosis (iSGS) is an unexplained progressive obstruction of the upper airway that occurs almost exclusively in adult, Caucasian women. The disease characterised by mucosal inflammation and localised fibrosis resulting life-threatening blockage airway. Because high recurrence rates, patients with iSGS will frequently require multiple procedures following their initial diagnosis. Both its therapies profoundly affect patients' ability to breathe, communicate swallow. A...
Review of clinical experience and results using botulinum toxin type A (BTX) for the management adult patients with respiratory compromise due to new onset bilateral vocal fold motion impairment (BVFMI).Retrospective case series.The records 11 from two institutions were reviewed. Age, sex, etiology impairment, subjective response BTX injections, changes in pulmonary function studies pre- postinjection when available, dosage required achieve response, number injections per patient,...
Objectives Idiopathic subglottic stenosis (iSGS) is rare, and its cause remains elusive. Treatment options include empiric medical therapy endoscopic or open surgery. We present our results for surgical technique. Study Design Case series with chart review (1978‐2015). Setting Tertiary academic center. Subjects/Methods Thirty‐three patients (32 female; median age, 51 years) met inclusion criteria underwent cricotracheal resection thyrotracheal anastomosis, tracheal primary...
Cysts of the vallecula are rare, accounting for 10.5% to 20.1% all laryngeal cysts. Vallecular cysts may present with diverse symptoms affecting voice, airway, and swallowing. We describe evaluation treatment a 70-year-old woman who presented dysphagia caused by large bilateral vallecular
<h3>Importance</h3> Refractory chronic cough is a debilitating condition with limited therapeutic options. Laryngeal botulinum toxin type A (BtxA) has been anecdotally reported to benefit patients cough. We report on our experience the use of BtxA for treatment refractory <h3>Objective</h3> To describe effects electromyography (EMG)-guided thyroarytenoid (TA) injection <h3>Design, Setting, and Participants</h3> For this single tertiary referral center retrospective case series, we included...
Multiple system atrophy (MSA) is a degenerative neurologic disorder that can affect vocal fold mobility. Our aim was to further elucidate the impact of motion impairment (VFMI) in MSA.Retrospective case series.We undertook retrospective review all MSA patients reporting voice or respiratory symptoms from 1975 2010 at Mayo Clinic Rochester who also received otolaryngologic examination.Thirty-eight demonstrated VFMI. Median duration prior diagnosis 12.0 months (range, 1-60 months). Stridor...
To describe the outcomes of patients undergoing open stapler versus transoral rigid and flexible endoscopic therapies for symptomatic Zenker's diverticulum.Single institution retrospective review.Tertiary care academic hospital.We retrospectively evaluated 424 consecutive who underwent diverticulotomy via an stapler, CO2 laser, harmonic scalpel, or technique from January 2006 to December 2020.A total (173 females, mean age 73.1 ± 11.2 years) a single were included. A 142 (33%) laser...
To report on a series of patients with cANCA/PR3-positive, granulomatosis polyangiitis (GPA)-associated subglottic stenosis (SGS) and evaluate response to medical maintenance therapy rituximab versus other immunosuppressants following initial endoscopic laser excision.
Analyze the duration of symptom-free intervals following laser wedge excision (LWE) for recurrent idiopathic subglottic stenosis (iSGS). Secondary aim includes evaluating influence patient-related or disease factors.
Objective Voice outcomes following medialization laryngoplasty (ML) for unilateral vocal fold paralysis (UVFP) were compared to those who underwent ML plus arytenoid adduction (AA) (ML+AA). Methods Single institution retrospective review of patients with UVFP undergoing and ML+AA (2009–2017). Demographic information history laryngeal procedures collected. Preoperative postoperative Handicap Index‐10 (VHI‐10) Consensus Perceptual Auditory Evaluation (CAPE‐V) assessed. Results Of 236 patients,...
Objective: To report a single institutional series of high-grade neuroendocrine carcinoma the larynx (NCL), very rare yet aggressive tumor. review management NCL, including discussion clinical behavior, treatment outcome, and prognosis. Method: A retrospective chart laryngeal carcinomas at institution, small- large-cell carcinomas. total 8 patients with NCL treated our institution from 1992 to 2014 were identified. Results: The median age diagnosis was 65.5 years (range, 43-80). Five male....
Idiopathic subglottic stenosis (iSGS) is a challenging and recurrent disease affecting Caucasian females with an unknown etiology multiple potential contributing factors.1 The most common method of management SGS includes endoscopic balloon or rigid dilation, often carbon dioxide (CO2) laser radial incisions prior to dilation.1 Balloon dilation does carry some risk including tracheal laceration, cricoid fracture, healthy trachea leading disruption normal mucosal tissue.2 First described in...